Doe
Acta Biochim Pol. 2004;51(2):471-80. Related Articles, Links
The role of labile iron pool in cardiovascular diseases.
Kruszewski M.
Department of Radiobiology and Health Protection, Institute
of Nuclear Chemistry and Technology, Warszawa, Poland.
Although multiple factors are associated with cardiovascular
pathology, there is now an impressive body of evidence that
free radicals and nonradical oxidants might cause a number
of cardiovascular dysfunctions. Both direct damage to
cellular components and/or oxidation of extracellular
biomolecules,
e.g. LDL, might be involved in the aetiology of
cardiovascular diseases. The key molecules in this
process seem to be iron and copper ions that catalyse
formation of the highly reactive hydroxyl radical.
Chelation of iron ions has a beneficial effect on the
processes associated with the development of
atherosclerosis and formation of post-ischemic lesions.
These findings are indirectly supported by the
increasing body of evidence that stored body iron plays
a crucial role in pathogenesis of atherosclerosis and
ischemia/reperfusion injury.
PMID: 15218543 [PubMed - in process]
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http://jesuswasavegetarian.7h.com (http://jesuswasavegetarian.7h.com/) Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking
The role of labile iron pool in cardiovascular diseases.
Kruszewski M.
Department of Radiobiology and Health Protection, Institute
of Nuclear Chemistry and Technology, Warszawa, Poland.
Although multiple factors are associated with cardiovascular
pathology, there is now an impressive body of evidence that
free radicals and nonradical oxidants might cause a number
of cardiovascular dysfunctions. Both direct damage to
cellular components and/or oxidation of extracellular
biomolecules,
e.g. LDL, might be involved in the aetiology of
cardiovascular diseases. The key molecules in this
process seem to be iron and copper ions that catalyse
formation of the highly reactive hydroxyl radical.
Chelation of iron ions has a beneficial effect on the
processes associated with the development of
atherosclerosis and formation of post-ischemic lesions.
These findings are indirectly supported by the
increasing body of evidence that stored body iron plays
a crucial role in pathogenesis of atherosclerosis and
ischemia/reperfusion injury.
PMID: 15218543 [PubMed - in process]
------------------------------------------------------------
--------------
------
Who loves ya. Tom Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com (http://jesuswasavegetarian.7h.com/) Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking
