Lantus and Arthralgias (body pain)
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I have been using Lantus for the past three months while in
other countries and now here. I have had severe body pain
especially low back with Sciatic involvement. Pain in the
buttocks and down the leg to the ankle with severe oedema.
The swelling is becoming less with the elimination of Lantus
and several days use of Bumex. Walking is very difficult and
I actually have almost ataxic movements. Stopped this
Insulin for three days and much of the problem has resolved.
I also have FM but now have very limited range of motion in
extremities. I am in PT and have been advised to use the
pool and Jacuzzi but I hate being in water other than a
shower. How about the use of a Gazelle? Anyone have one and
used it successfully. It is used by many of the spinal
institutes for a walking like exercise with no joint
compression. I will be exchanging my Tunturi exercycle for
another type with an upright seat position as this backward
extension hurts more that it does good. Really don't want to
go back on the pump while traveling as it is so inconvenient
but then I don't need Lantus.
Thanks, Quilty
In any case, you should not use a drug you think is causing trouble.
Most of us don't see these problems.. I do have a lot of problems but
they were there before Lantus. Consult with a good doc.
.Guy
On Sun, 27 Jun 2004 14:53:18 -0700, kiltyone@dslextreme.com wrote:
> I have been using Lantus for the past three months while
> in other countries and now here. I have had severe body
> pain especially low back with Sciatic involvement. Pain
> in the buttocks and down the leg to the ankle with
> severe oedema. The swelling is becoming less with the
> elimination of Lantus and several days use of Bumex.
> Walking is very difficult and I actually have almost
> ataxic movements. Stopped this Insulin for three days
> and much of the problem has resolved. I also have FM but
> now have very limited range of motion in extremities. I
> am in PT and have been advised to use the pool and
> Jacuzzi but I hate being in water other than a shower.
> How about the use of a Gazelle? Anyone have one and used
> it successfully. It is used by many of the spinal
> institutes for a walking like exercise with no joint
> compression. I will be exchanging my Tunturi exercycle
> for another type with an upright seat position as this
> backward extension hurts more that it does good. Really
> don't want to go back on the pump while traveling as it
> is so inconvenient but then I don't need Lantus.
>
> Thanks, Quilty
Quilty, I've been on Lantus for a few years, and have
never had a problem with it. Sorry that it has not gone so
well for you.
In regards to the Gazelle, I have never used it. However, my
sister (she has a bad knee) LOVES using it.
Steph
<kiltyone@dslextreme.com> wrote in message
news:10duge4ahgst3e6@corp.supernews.com...
> I have been using Lantus for the past three months
> while in other countries and now here. I have had
> severe body pain especially low back with Sciatic
> involvement. Pain in the buttocks and down the leg to
> the ankle with severe oedema. The swelling is becoming
> less with the elimination of Lantus and several days
> use of Bumex. Walking is very difficult and I actually
> have almost ataxic movements. Stopped this Insulin for
> three days and much of the problem has resolved. I also
> have FM but now have very limited range of motion in
> extremities. I am in PT and have been advised to use
> the pool and Jacuzzi but I hate being in water other
> than a shower. How about the use of a Gazelle? Anyone
> have one and used it successfully. It is used by many
> of the spinal institutes for a walking like exercise
> with no joint compression. I will be exchanging my
> Tunturi exercycle for another type with an upright seat
> position as this backward extension hurts more that it
> does good. Really don't want to go back on the pump
> while traveling as it is so inconvenient but then I
> don't need Lantus.
>
> Thanks, Quilty
Quilty,
I haven't seen any reports similar to yours anywhere in the
literature, or on the FDA site.
Lantus is now the #1 most prescribed insulin in the USA, so
there is quite a large experience with it.
While the probability is that your symptoms are from a
different source, it would be a good idea to get check by
your doc, and have him file a report to the FDA on Medwatch.
Cheers, William C Biggs, MD
<kiltyone@dslextreme.com> wrote in message
news:10duge4ahgst3e6@corp.supernews.com...
> I have been using Lantus for the past three months
> while in other countries and now here. I have had
> severe body pain especially low back with Sciatic
> involvement. Pain in the buttocks and down the leg to
> the ankle with severe oedema. The swelling is becoming
> less with the elimination of Lantus and several days
> use of Bumex. Walking is very difficult and I actually
> have almost ataxic movements. Stopped this Insulin for
> three days and much of the problem has resolved. I also
> have FM but now have very limited range of motion in
> extremities. I am in PT and have been advised to use
> the pool and Jacuzzi but I hate being in water other
> than a shower. How about the use of a Gazelle? Anyone
> have one and used it successfully. It is used by many
> of the spinal institutes for a walking like exercise
> with no joint compression. I will be exchanging my
> Tunturi exercycle for another type with an upright seat
> position as this backward extension hurts more that it
> does good. Really don't want to go back on the pump
> while traveling as it is so inconvenient but then I
> don't need Lantus.
>
> Thanks, Quilty
Hey Quilty, I was told last week to up my swimming as well.
I have a lot of pain in my si joint area and I too get tired
of swimming and thought about the Gazelle. Let me know what
you find out ok. I am in abed a lot of days due to the pain
is so intense. My hips lock and I ache so bad..... Swimming
at least keeps the muscles from turning to mush.
Patricia <kiltyone@dslextreme.com> wrote in message
news:10duge4ahgst3e6@corp.supernews.com...
> I have been using Lantus for the past three months while
> in other countries and now here. I have had severe body
> pain especially low back with Sciatic involvement. Pain
> in the buttocks and down the leg to the ankle with
> severe oedema. The swelling is becoming less with the
> elimination of Lantus and several days use of Bumex.
> Walking is very difficult and I actually have almost
> ataxic movements. Stopped this Insulin for three days
> and much of the problem has resolved. I also have FM but
> now have very limited range of motion in extremities. I
> am in PT and have been advised to use the pool and
> Jacuzzi but I hate being in water other than a shower.
> How about the use of a Gazelle? Anyone have one and used
> it successfully. It is used by many of the spinal
> institutes for a walking like exercise with no joint
> compression. I will be exchanging my Tunturi exercycle
> for another type with an upright seat position as this
> backward extension hurts more that it does good. Really
> don't want to go back on the pump while traveling as it
> is so inconvenient but then I don't need Lantus.
>
> Thanks, Quilty
Thank you,
I have run through the problem with my Endo and its a "hands thrown
up in the air thing." I noticed in one report that this was a problem
and whether it was listed in the prescribing info or another report I
can't recall. Short term memory and all that. I will keep on looking
for the report in Medline.
This is almost textbook symptomology of Sciatic nerve involvement.
Will continue to root about until I find an answer. I am not fond of
the pump as one gains too much weight and the excessive amount of
supporting equipment hauled around to keep it going is cumbersome.
Kilty
William C Biggs MD wrote:
> Quilty,
>
> I haven't seen any reports similar to yours anywhere in
> the literature, or on the FDA site.
>
> Lantus is now the #1 most prescribed insulin in the USA,
> so there is quite a large experience with it.
>
> While the probability is that your symptoms are from a
> different source, it would be a good idea to get check by
> your doc, and have him file a report to the FDA on
> Medwatch.
>
> Cheers, William C Biggs, MD
>
>
> <kiltyone@dslextreme.com> wrote in message
> news:10duge4ahgst3e6@corp.supernews.com...
>
>> I have been using Lantus for the past three months
>> while in other countries and now here. I have had
>> severe body pain especially low back with Sciatic
>> involvement. Pain in the buttocks and down the leg to
>> the ankle with severe oedema. The swelling is becoming
>> less with the elimination of Lantus and several days
>> use of Bumex. Walking is very difficult and I actually
>> have almost ataxic movements. Stopped this Insulin for
>> three days and much of the problem has resolved. I also
>> have FM but now have very limited range of motion in
>> extremities. I am in PT and have been advised to use
>> the pool and Jacuzzi but I hate being in water other
>> than a shower. How about the use of a Gazelle? Anyone
>> have one and used it successfully. It is used by many
>> of the spinal institutes for a walking like exercise
>> with no joint compression. I will be exchanging my
>> Tunturi exercycle for another type with an upright seat
>> position as this backward extension hurts more that it
>> does good. Really don't want to go back on the pump
>> while traveling as it is so inconvenient but then I
>> don't need Lantus.
>>
>> Thanks, Quilty
>>
>
Your symptoms are very much like mine. Are you using Lantus?
Will let you know about the Gazelle. I am planning a visit
to the Spinal Institute of the Desert where they use it a
lot. I just don't want to buy another piece of exercise
equipment that I won't use. Will let you know what I find
out. Kilty
Patricia1966wa wrote:
> Hey Quilty, I was told last week to up my swimming as
> well. I have a lot of pain in my si joint area and I too
> get tired of swimming and thought about the Gazelle. Let
> me know what you find out ok. I am in abed a lot of days
> due to the pain is so intense. My hips lock and I ache so
> bad..... Swimming at least keeps the muscles from turning
> to mush.
>
> Patricia <kiltyone@dslextreme.com> wrote in message
> news:10duge4ahgst3e6@corp.supernews.com...
>
>> I have been using Lantus for the past three months while
>> in other countries and now here. I have had severe body
>> pain especially low back with Sciatic involvement. Pain
>> in the buttocks and down the leg to the ankle with
>> severe oedema. The swelling is becoming less with the
>> elimination of Lantus and several days use of Bumex.
>> Walking is very difficult and I actually have almost
>> ataxic movements. Stopped this Insulin for three days
>> and much of the problem has resolved. I also have FM but
>> now have very limited range of motion in extremities. I
>> am in PT and have been advised to use the pool and
>> Jacuzzi but I hate being in water other than a shower.
>> How about the use of a Gazelle? Anyone have one and used
>> it successfully. It is used by many of the spinal
>> institutes for a walking like exercise with no joint
>> compression. I will be exchanging my Tunturi exercycle
>> for another type with an upright seat position as this
>> backward extension hurts more that it does good. Really
>> don't want to go back on the pump while traveling as it
>> is so inconvenient but then I don't need Lantus.
>>
>> Thanks, Quilty
>>
>
Steph, Thanks for the info on the Gazelle. Does it provide a
no impact work out as is implied? Did she also lose weight
using it? Need to do that too. Using the pump caused a
weight gain. Kilty
Stephanie Kolban wrote:
> Quilty, I've been on Lantus for a few years, and have
> never had a problem with it. Sorry that it has not gone so
> well for you.
>
> In regards to the Gazelle, I have never used it. However,
> my sister (she has a bad knee) LOVES using it.
>
> Steph
>
> <kiltyone@dslextreme.com> wrote in message
> news:10duge4ahgst3e6@corp.supernews.com...
>
>> I have been using Lantus for the past three months
>> while in other countries and now here. I have had
>> severe body pain especially low back with Sciatic
>> involvement. Pain in the buttocks and down the leg to
>> the ankle with severe oedema. The swelling is becoming
>> less with the elimination of Lantus and several days
>> use of Bumex. Walking is very difficult and I actually
>> have almost ataxic movements. Stopped this Insulin for
>> three days and much of the problem has resolved. I also
>> have FM but now have very limited range of motion in
>> extremities. I am in PT and have been advised to use
>> the pool and Jacuzzi but I hate being in water other
>> than a shower. How about the use of a Gazelle? Anyone
>> have one and used it successfully. It is used by many
>> of the spinal institutes for a walking like exercise
>> with no joint compression. I will be exchanging my
>> Tunturi exercycle for another type with an upright seat
>> position as this backward extension hurts more that it
>> does good. Really don't want to go back on the pump
>> while traveling as it is so inconvenient but then I
>> don't need Lantus.
>>
>> Thanks, Quilty
>>
>
According to my sister, it is no impact. And, yes, she lost
some weight. Steph
<kiltyone@dslextreme.com> wrote in message
news:10e0q9sb8m28t7d@corp.supernews.com...
> Steph, Thanks for the info on the Gazelle. Does it
> provide a no impact work out as is implied? Did she
> also lose weight using it? Need to do that too. Using
> the pump caused a weight gain. Kilty
>
> Stephanie Kolban wrote:
>
> > Quilty, I've been on Lantus for a few years, and have
> > never had a problem with
it.
> > Sorry that it has not gone so well for you.
> >
> > In regards to the Gazelle, I have never used it.
> > However, my sister
(she
> > has a bad knee) LOVES using it.
> >
> > Steph
> >
> > <kiltyone@dslextreme.com> wrote in message
> > news:10duge4ahgst3e6@corp.supernews.com...
> >
> >> I have been using Lantus for the past three months
> >> while in other countries and now here. I have had
> >> severe body pain especially low back with Sciatic
> >> involvement. Pain in the buttocks and down the leg to
> >> the ankle with severe oedema. The swelling is
> >> becoming less with the elimination of Lantus and
> >> several days use of Bumex. Walking is very difficult
> >> and I actually have almost ataxic
movements.
> >>Stopped this Insulin for three days and much of the
> >>problem has resolved. I also have FM but now have very
> >>limited range of motion in extremities. I am in PT and
> >>have been advised to use the pool and Jacuzzi but I hate
> >>being in water other than a shower. How about the use of
> >>a Gazelle? Anyone have one and used it successfully. It
> >>is used by many of the spinal institutes for a walking
> >>like exercise with no joint compression. I will be
> >>exchanging my Tunturi exercycle for another type with an
> >>upright seat position as this backward extension hurts
> >>more that it does good. Really don't want to go back on
> >>the pump while traveling as it is so inconvenient but
> >>then I don't need Lantus.
> >>
> >> Thanks, Quilty
> >>
> >
> >
Quilty,
There actually is a large body of literature about sciatic
nerve pain in diabetes. This is a common problem in
diabetes, and is typically self limited. It can be an
extreme nuisance for the duration.
IMHO we see less weight gain with pumps compared to previous
years because we push carb counting harder now. In the "old
days" we used a preset meal dose plus a correction factor
for the glucose. Now we use carb counting that matches the
food and insulin dose better, and people need fewer snacks
to reverse hypos.
Thus pumps might deserve another look.
Cheers, William C Biggs, MD
<kiltyone@dslextreme.com> wrote in message
news:10e0q1bol21in33@corp.supernews.com...
> Thank you, I have run through the problem with my Endo
> and its a "hands thrown up in the air thing." I noticed
> in one report that this was a problem and whether it
> was listed in the prescribing info or another report I
> can't recall. Short term memory and all that. I will
> keep on looking for the report in Medline. This is
> almost textbook symptomology of Sciatic nerve
> involvement. Will continue to root about until I find
> an answer. I am not fond of the pump as one gains too
> much weight and the excessive amount of supporting
> equipment hauled around to keep it going is cumbersome.
> Kilty William C Biggs MD wrote:
> > Quilty,
> >
> > I haven't seen any reports similar to yours anywhere in
> > the literature,
or
> > on the FDA site.
> >
> > Lantus is now the #1 most prescribed insulin in the USA,
> > so there is
quite a
> > large experience with it.
> >
> > While the probability is that your symptoms are from a
> > different source,
it
> > would be a good idea to get check by your doc, and have
> > him file a
report to
> > the FDA on Medwatch.
> >
> > Cheers, William C Biggs, MD
> >
> >
> > <kiltyone@dslextreme.com> wrote in message
> > news:10duge4ahgst3e6@corp.supernews.com...
> >
> >> I have been using Lantus for the past three months
> >> while in other countries and now here. I have had
> >> severe body pain especially low back with Sciatic
> >> involvement. Pain in the buttocks and down the leg to
> >> the ankle with severe oedema. The swelling is
> >> becoming less with the elimination of Lantus and
> >> several days use of Bumex. Walking is very difficult
> >> and I actually have almost ataxic
movements.
> >>Stopped this Insulin for three days and much of the
> >>problem has resolved. I also have FM but now have very
> >>limited range of motion in extremities. I am in PT and
> >>have been advised to use the pool and Jacuzzi but I hate
> >>being in water other than a shower. How about the use of
> >>a Gazelle? Anyone have one and used it successfully. It
> >>is used by many of the spinal institutes for a walking
> >>like exercise with no joint compression. I will be
> >>exchanging my Tunturi exercycle for another type with an
> >>upright seat position as this backward extension hurts
> >>more that it does good. Really don't want to go back on
> >>the pump while traveling as it is so inconvenient but
> >>then I don't need Lantus.
> >>
> >> Thanks, Quilty
> >>
> >
> >
kiltyone@dslextreme.com wrote:
> Thank you, I have run through the problem with my Endo
> and its a "hands thrown up in the air thing." I noticed
> in one report that this was a problem and whether it was
> listed in the prescribing info or another report I can't
> recall. Short term memory and all that. I will keep on
> looking for the report in Medline.
>
> This is almost textbook symptomology of Sciatic nerve
> involvement. Will continue to root about until I find an
> answer. I am not fond of the pump as one gains too much
> weight and the excessive amount of supporting equipment
> hauled around to keep it going is cumbersome. Kilty
see below for a possible idea
> William C Biggs MD wrote:
>
>> Quilty,
>>
>> I haven't seen any reports similar to yours anywhere in
>> the literature, or on the FDA site.
>>
>> Lantus is now the #1 most prescribed insulin in the USA,
>> so there is quite a large experience with it.
the odds are that doc biggs ir right, but strange problems
can and do happen with new insulin and tend to take anywhere
from 2-to-6 years (or more) to get recognized
that's certainly been true with both "human" insulin and
more recently with these weird analog insulins, the oldest
of which is lispro
>>
>> While the probability is that your symptoms are from a
>> different source, it would be a good idea to get check by
>> your doc, and have him file a a report to the FDA on
>> Medwatch.
i wouldn't do that until you have some real confidence that
the problem is caused by Lantus
i.e. that the problem is either being caused *fully* by the
use of Lantus, or possibly by some more complex thing
where Lantus is only partly at fault
assuming you are type-1 and using Lantus 2x (which is how
most type-1 diabetics are using Lantus), to my mind the
easiest way to find out about Lantus would be to ditch
Lantus completely and go to using Lilly's "human"-UL 2x
for one thing, all of the UL insulins ("human" and pork and
beef) are more robust and don't have to be babied like
Lantus does, not to mention that "human"-UL costs about half
what you have to pay for lantus. fact is that only beef-UL
is flat at the 24 hour mark with 1x dosing
if Lantus has any real advantages over any of the UL
insulins, i'm so far still unaware of it
even though "human"-UL is sold OTC in the USA, be sure to
check with your real doc before switching insulin. :)
bill t1 since '57 ex 8-yr pumper, pork/beef-L 2x,
simple MDI/DAFNE
>>
>> Cheers, William C Biggs, MD
Thanks, I will look into it.
Stephanie Kolban wrote:
> According to my sister, it is no impact. And, yes, she
> lost some weight. Steph
>
> <kiltyone@dslextreme.com> wrote in message
> news:10e0q9sb8m28t7d@corp.supernews.com...
>
>> Steph, Thanks for the info on the Gazelle. Does it
>> provide a no impact work out as is implied? Did she
>> also lose weight using it? Need to do that too. Using
>> the pump caused a weight gain. Kilty
>>
>>Stephanie Kolban wrote:
>>
>>
>>>Quilty, I've been on Lantus for a few years, and have
>>>never had a problem with
>
> it.
>
>>>Sorry that it has not gone so well for you.
>>>
>>>In regards to the Gazelle, I have never used it. However,
>>>my sister
>
> (she
>
>>>has a bad knee) LOVES using it.
>>>
>>>Steph
>>>
>>><kiltyone@dslextreme.com> wrote in message
>>>news:10duge4ahgst3e6@corp.supernews.com...
>>>
>>>
>>>> I have been using Lantus for the past three months
>>>> while in other countries and now here. I have had
>>>> severe body pain especially low back with Sciatic
>>>> involvement. Pain in the buttocks and down the leg to
>>>> the ankle with severe oedema. The swelling is becoming
>>>> less with the elimination of Lantus and several days
>>>> use of Bumex. Walking is very difficult and I actually
>>>> have almost ataxic
>
> movements.
>
>>>>Stopped this Insulin for three days and much of the
>>>>problem has resolved. I also have FM but now have very
>>>>limited range of motion in extremities. I am in PT and
>>>>have been advised to use the pool and Jacuzzi but I hate
>>>>being in water other than a shower. How about the use of
>>>>a Gazelle? Anyone have one and used it successfully. It
>>>>is used by many of the spinal institutes for a walking
>>>>like exercise with no joint compression. I will be
>>>>exchanging my Tunturi exercycle for another type with an
>>>>upright seat position as this backward extension hurts
>>>>more that it does good. Really don't want to go back on
>>>>the pump while traveling as it is so inconvenient but
>>>>then I don't need Lantus.
>>>>
>>>> Thanks, Quilty
>>>>
>>>
>>>
>>>
Thanks again for your cogent reply. I have a MM 508 and will
be getting a new one as the present unit seems very prone to
ESD. I will return to its use when I finish my PT for this
back. Prior to my disconnect I was using Quick-Set and loved
them. So easy to use when you Jacuzzi and do pool exercise
every day. I stopped the Lantus for two days and evidently
there was enough residual to last a couple of days. Don't
know it there is a wash-out time with that Insulin or not.
The Sciatic problems and other nerve involvement are very
common as I understand especially after the 25+ year mark. I
do have increased risk for spinal problems due to rather
severe Osteo of the L & S spine. A number of facet
involvements and the usual and customary supportive
problems. As to the carb situation I just can not justify a
LC diet. Too much protein at this late date and my kidneys
will object. So I do modify this type of diet with mainly
chicken in small amounts and wild salmon in larger servings.
I just can't do without carbs as some do and evidently
successfully so, for now. In our house we make our own
breads and find certain types of starches just fine. Again
much thanks for your help and good info it is definitely
appreciated. Kilty
William C Biggs MD wrote:
> Quilty,
>
> There actually is a large body of literature about sciatic
> nerve pain in diabetes. This is a common problem in
> diabetes, and is typically self limited. It can be an
> extreme nuisance for the duration.
>
> IMHO we see less weight gain with pumps compared to
> previous years because we push carb counting harder now.
> In the "old days" we used a preset meal dose plus a
> correction factor for the glucose. Now we use carb
> counting that matches the food and insulin dose better,
> and people need fewer snacks to reverse hypos.
>
> Thus pumps might deserve another look.
>
> Cheers, William C Biggs, MD
>
> <kiltyone@dslextreme.com> wrote in message
> news:10e0q1bol21in33@corp.supernews.com...
>
>> Thank you, I have run through the problem with my Endo
>> and its a "hands thrown up in the air thing." I noticed
>> in one report that this was a problem and whether it
>> was listed in the prescribing info or another report I
>> can't recall. Short term memory and all that. I will
>> keep on looking for the report in Medline. This is
>> almost textbook symptomology of Sciatic nerve
>> involvement. Will continue to root about until I find
>> an answer. I am not fond of the pump as one gains too
>> much weight and the excessive amount of supporting
>> equipment hauled around to keep it going is cumbersome.
>> Kilty William C Biggs MD wrote:
>>
>>>Quilty,
>>>
>>>I haven't seen any reports similar to yours anywhere in
>>>the literature,
>
> or
>
>>>on the FDA site.
>>>
>>>Lantus is now the #1 most prescribed insulin in the USA,
>>>so there is
>
> quite a
>
>>>large experience with it.
>>>
>>>While the probability is that your symptoms are from a
>>>different source,
>
> it
>
>>>would be a good idea to get check by your doc, and have
>>>him file a
>
> report to
>
>>>the FDA on Medwatch.
>>>
>>>Cheers, William C Biggs, MD
>>>
>>>
>>><kiltyone@dslextreme.com> wrote in message
>>>news:10duge4ahgst3e6@corp.supernews.com...
>>>
>>>
>>>> I have been using Lantus for the past three months
>>>> while in other countries and now here. I have had
>>>> severe body pain especially low back with Sciatic
>>>> involvement. Pain in the buttocks and down the leg to
>>>> the ankle with severe oedema. The swelling is becoming
>>>> less with the elimination of Lantus and several days
>>>> use of Bumex. Walking is very difficult and I actually
>>>> have almost ataxic
>
> movements.
>
>>>>Stopped this Insulin for three days and much of the
>>>>problem has resolved. I also have FM but now have very
>>>>limited range of motion in extremities. I am in PT and
>>>>have been advised to use the pool and Jacuzzi but I hate
>>>>being in water other than a shower. How about the use of
>>>>a Gazelle? Anyone have one and used it successfully. It
>>>>is used by many of the spinal institutes for a walking
>>>>like exercise with no joint compression. I will be
>>>>exchanging my Tunturi exercycle for another type with an
>>>>upright seat position as this backward extension hurts
>>>>more that it does good. Really don't want to go back on
>>>>the pump while traveling as it is so inconvenient but
>>>>then I don't need Lantus.
>>>>
>>>> Thanks, Quilty
>>>>
>>>
>>>
>>>
Thank you for the information.
willbill wrote:
> kiltyone@dslextreme.com wrote:
>
>> Thank you, I have run through the problem with my Endo
>> and its a "hands thrown up in the air thing." I noticed
>> in one report that this was a problem and whether it
>> was listed in the prescribing info or another report I
>> can't recall. Short term memory and all that. I will
>> keep on looking for the report in Medline.
>>
>> This is almost textbook symptomology of Sciatic nerve
>> involvement. Will continue to root about until I find
>> an answer. I am not fond of the pump as one gains too
>> much weight and the excessive amount of supporting
>> equipment hauled around to keep it going is cumbersome.
>> Kilty
>
>
> see below for a possible idea
>
>
>> William C Biggs MD wrote:
>>
>>> Quilty,
>>>
>>> I haven't seen any reports similar to yours anywhere in
>>> the literature, or on the FDA site.
>>>
>>> Lantus is now the #1 most prescribed insulin in the USA,
>>> so there is quite a large experience with it.
>
>
>
> the odds are that doc biggs ir right, but strange problems
> can and do happen with new insulin and tend to take
> anywhere from 2-to-6 years (or more) to get recognized
>
> that's certainly been true with both "human" insulin and
> more recently with these weird analog insulins, the oldest
> of which is lispro
>
>>>
>>> While the probability is that your symptoms are from a
>>> different source, it would be a good idea to get check
>>> by your doc, and have him file a a report to the FDA on
>>> Medwatch.
>
>
>
> i wouldn't do that until you have some real confidence
> that the problem is caused by Lantus
>
> i.e. that the problem is either being caused *fully* by
> the use of Lantus, or possibly by some more complex
> thing where Lantus is only partly at fault
>
> assuming you are type-1 and using Lantus 2x (which is how
> most type-1 diabetics are using Lantus), to my mind the
> easiest way to find out about Lantus would be to ditch
> Lantus completely and go to using Lilly's "human"-UL 2x
>
> for one thing, all of the UL insulins ("human" and pork
> and beef) are more robust and don't have to be babied like
> Lantus does, not to mention that "human"-UL costs about
> half what you have to pay for lantus. fact is that only
> beef-UL is flat at the 24 hour mark with 1x dosing
>
> if Lantus has any real advantages over any of the UL
> insulins, i'm so far still unaware of it
>
> even though "human"-UL is sold OTC in the USA, be sure to
> check with your real doc before switching insulin. :)
>
> bill t1 since '57 ex 8-yr pumper, pork/beef-L 2x, simple
> MDI/DAFNE
>
>
>>>
>>> Cheers, William C Biggs, MD
>
>
>
Bill,
> >> While the probability is that your symptoms are from a
> >> different source, it would be a good idea to get check
> >> by your doc, and have him file a a report to the FDA on
> >> Medwatch.
>
>
> i wouldn't do that until you have some real confidence
> that the problem is caused by Lantus
Actually the FDA, and most docs, prefer to report any
problem that happens, even if it is possibly a mere
coincidence. Most of the time it is unclear whether there is
any cause and effect, particularly on new drug products.
If the FDA gets enough reports of the same problem, it will
launch an investigation into the issue. You don't have to be
sure that there is a cause and effect.
If we didn't have this kind of reporting, it would allow
potentially dangerous drugs to stay on the market longer.
Rezulin got pulled because of the Medwatch database reports
that were accumulating.
Even if it doesn't cause removal of the drug from the
market, it might cause a warning statement to be issued that
would benefit any future patients when they consider taking
the product.
I make reports any time I have even a suspicion of a problem
with a product or a drug. I have made reports on insulin
pump infusion sets, Zyprexa, insulin pumps, thyroid meds,
and Rezulin, among others.
I also search the product reports if I suspect a problem, to
see if it has been described before.
Reporting is easy, simply visit the FDA web site.
http://www.fda.gov/medwatch/
Cheers, William C Biggs, MD
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