Dr. Jai Maharaj
Immune modulation therapy, latest treatment for people with
chronic heart failure
Posted By: News-Medical in Medical Procedure News Published:
Tuesday, 29-Jun-2004
Here is the latest treatment for people with chronic heart
failure: a nurse draws blood from the patient, runs that
blood through a machine, superheating and "stressing" the
blood, and then, injects it back into the patient.
It sounds like science fiction -- and too simple to be true.
But that is exactly what cardiologists at the University of
Calgary Faculty of Medicine are doing in a clinical trial
launched today.
The ACCLAIM study is a double-blind, Phase 3 clinical trial
enrolling 2000 people with chronic heart failure across
North America. Clinical research sites include Sacramento,
Montreal, Dallas, Cleveland, Boston, and Calgary.
"We cardiologists have recently come to understand that
inflammation plays a pivotal role in the development and
progression of heart failure," says Dr. Debra Isaac,
associate clinical professor of cardiology, U of C Faculty
of Medicine. "This procedure targets chronic inflammation by
kick-starting the immune system's own anti-inflammatory
response."
The procedure, known as immune modulation therapy, involves
the following: a nurse takes 10 cc's (about 2 teaspoons) of
blood from a patient, and puts that blood into a specialized
machine that applies stresses: heat, oxidation, and UV
light. When white blood cells experience this stress, they
begin to die. The nurse then re-injects that blood back into
the patient's leg muscle. The dying cells trigger an anti-
inflammatory reaction in the patient, inducing his/her body
to boost its own anti- inflammatory processes.
"It is critical that we slow down the inflammatory process
that is toxic to the heart," says Dr. Jean Rouleau, dean,
Faculty of Medicine, Université de Montréal, and principal
investigator of the study for Canada. "Our hope is that this
potential treatment can alleviate the serious side-effects
of chronic heart failure, and treat the long-term damage
being caused by the disease."
Phase 2 clinical trials found that this procedure was
beneficial to a significant number of patients, resulting in
fewer hospitalizations, better quality of life, improved
clinical status, and fewer deaths due to the devastating
effects of heart failure.
Dr. Isaac, principal investigator of ACCLAIM in Calgary, and
director, cardiac transplantation program, Calgary
Health Region, is aiming to recruit 30 people who will
undergo the 20-minute procedure on an outpatient basis
once a month for 2 years.
http://www.ucalgary.ca (http://www.ucalgary.ca/)
More at: http://www.news-medical.net/?id=2916
Jai Maharaj http://www.mantra.com/jai Om Shanti
Hindu Holocaust Museum http://www.mantra.com/holocaust
Hindu life, principles, spirituality and philosophy
http://www.hindu.org (http://www.hindu.org/) http://www.hindunet.org (http://www.hindunet.org/)
The truth about Islam and Muslims
http://www.flex.com/~jai/satyamevajayate
The terrorist mission of Jesus stated in the Christian
bible:
"Think not that I am come to send peace on earth: I
came not so send peace, but a sword. "For I am come to
set a man at variance against his father, and the
daughter against her mother, and the daughter in law
against her mother in law. "And a man's foes shall be
they of his own household.
- Matthew 10:34-36.
o Not for commercial use. Solely to be fairly used
for the educational purposes of research and open
discussion. The contents of this post may not have
been authored by, and do not necessarily represent
the opinion of the poster. The contents are protected
by copyright law and the exemption for fair use of
copyrighted works. o If you send private e-mail to
me, it will likely not be read, considered or
answered if it does not contain your full legal name,
current e-mail and postal addresses, and live-voice
telephone number. o Posted for information and
discussion. Views expressed by others are not
necessarily those of the poster.
chronic heart failure
Posted By: News-Medical in Medical Procedure News Published:
Tuesday, 29-Jun-2004
Here is the latest treatment for people with chronic heart
failure: a nurse draws blood from the patient, runs that
blood through a machine, superheating and "stressing" the
blood, and then, injects it back into the patient.
It sounds like science fiction -- and too simple to be true.
But that is exactly what cardiologists at the University of
Calgary Faculty of Medicine are doing in a clinical trial
launched today.
The ACCLAIM study is a double-blind, Phase 3 clinical trial
enrolling 2000 people with chronic heart failure across
North America. Clinical research sites include Sacramento,
Montreal, Dallas, Cleveland, Boston, and Calgary.
"We cardiologists have recently come to understand that
inflammation plays a pivotal role in the development and
progression of heart failure," says Dr. Debra Isaac,
associate clinical professor of cardiology, U of C Faculty
of Medicine. "This procedure targets chronic inflammation by
kick-starting the immune system's own anti-inflammatory
response."
The procedure, known as immune modulation therapy, involves
the following: a nurse takes 10 cc's (about 2 teaspoons) of
blood from a patient, and puts that blood into a specialized
machine that applies stresses: heat, oxidation, and UV
light. When white blood cells experience this stress, they
begin to die. The nurse then re-injects that blood back into
the patient's leg muscle. The dying cells trigger an anti-
inflammatory reaction in the patient, inducing his/her body
to boost its own anti- inflammatory processes.
"It is critical that we slow down the inflammatory process
that is toxic to the heart," says Dr. Jean Rouleau, dean,
Faculty of Medicine, Université de Montréal, and principal
investigator of the study for Canada. "Our hope is that this
potential treatment can alleviate the serious side-effects
of chronic heart failure, and treat the long-term damage
being caused by the disease."
Phase 2 clinical trials found that this procedure was
beneficial to a significant number of patients, resulting in
fewer hospitalizations, better quality of life, improved
clinical status, and fewer deaths due to the devastating
effects of heart failure.
Dr. Isaac, principal investigator of ACCLAIM in Calgary, and
director, cardiac transplantation program, Calgary
Health Region, is aiming to recruit 30 people who will
undergo the 20-minute procedure on an outpatient basis
once a month for 2 years.
http://www.ucalgary.ca (http://www.ucalgary.ca/)
More at: http://www.news-medical.net/?id=2916
Jai Maharaj http://www.mantra.com/jai Om Shanti
Hindu Holocaust Museum http://www.mantra.com/holocaust
Hindu life, principles, spirituality and philosophy
http://www.hindu.org (http://www.hindu.org/) http://www.hindunet.org (http://www.hindunet.org/)
The truth about Islam and Muslims
http://www.flex.com/~jai/satyamevajayate
The terrorist mission of Jesus stated in the Christian
bible:
"Think not that I am come to send peace on earth: I
came not so send peace, but a sword. "For I am come to
set a man at variance against his father, and the
daughter against her mother, and the daughter in law
against her mother in law. "And a man's foes shall be
they of his own household.
- Matthew 10:34-36.
o Not for commercial use. Solely to be fairly used
for the educational purposes of research and open
discussion. The contents of this post may not have
been authored by, and do not necessarily represent
the opinion of the poster. The contents are protected
by copyright law and the exemption for fair use of
copyrighted works. o If you send private e-mail to
me, it will likely not be read, considered or
answered if it does not contain your full legal name,
current e-mail and postal addresses, and live-voice
telephone number. o Posted for information and
discussion. Views expressed by others are not
necessarily those of the poster.
