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Obesity / elevated iron

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http://www.nature.com/cgi-taf/DynaPage.taf?file=/ijo/journal/v25/n5/abs/08
01561a.html

May 2001, Volume 25, Number 5, Pages 639-645
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Paper
Association of serum ferritin and indices of body fat distribution and obesity
in Mexican American menžthe Third National Health and Nutrition Examination
Survey

R F Gillum

Centers for Disease Control and Prevention, Hyattsville, Maryland, USA


Correspondence to: R F Gillum, Centers for Disease Control and Prevention,
National Center for Health Statistics, 6525 Belcrest Road, Room 730,
Hyattsville, MD 20782, USA


Abstract

BACKGROUND: Few data have been published on the association of indices of body
fat distribution and serum ferritin, an indicator of body iron stores and
putative risk factor for cardiovascular morbidity, in representative samples of
total populations or in Hispanic Americans.

OBJECTIVE: To describe the distributions of serum ferritin concentration and
waist-to-hip ratio (WHR) in Mexican American men and to assess their
association.

DESIGN: Cross-sectional survey of a large national sample, the Third National
Health and Nutrition Examination Survey.

PARTICIPANTS: Mexican American men aged 20-49 y.

MEASUREMENTS: Body circumferences, skinfold thickness, height, weight, and
serum ferritin and C-reactive protein concentrations.

RESULTS: Mean serum ferritin increased between ages 20 and 29 but not between
30 and 49. WHR increased with age between ages 20 and 49. WHR showed
significant positive associations with log serum ferritin concentration
independent of age and body mass index (BMI). The association was strongest at
age 20-29 y among those with BMI below the median. Associations with other
indices of body fat distribution and overall obesity are described.

CONCLUSION: Serum ferritin concentration is associated with WHR and other
indices of body fat distribution and obesity. Further research is needed to
elucidate the mechanisms and significance of these findings.

International Journal of Obesity (2001) 25, 639-645


Keywords

ferritin, serum; Hispanics; male; adipose tissue; age factors; obesity

Received 21 April 2000; revised 25 October 2000; accepted 1 November 2000

May 2001, Volume 25, Number 5, Pages 639-645


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