Ibuprofen before Vo2 max workouts? You too? - Page 3

If it does, it is via a placebo effect.

As for the lack of "...readily apparent ill effects...", I hope that you are aware that in addition to inhibit muscle protein synthesis during post-exercise recovery, use of NSAIDS before/during exercise has on occasion been linked to kidney failure. The proposed mechanism of action is blockade of the protective anti-vasoconstrictive action of renal prostaglandin production.

if that is correct, why would Bicycling Magazine publish results that are the direct opposite of what you are saying? Albeit the results are in older individuals, but they seem positive (see my post just before yours). I don't mean to be interrogative or to attack your knowledge, please don't take it the wrong way. I'm just curious about this subject. But it does seem that there are a lot of differing opinions on this topic. Am I wrong?

I have no idea what Bicycling! might have had to say on the subject. I will say, however, that I tend to place more trust in the primary scientific literature than any lay magazine (and I say that despite being contacted by Bicycling! on more than one occasion).

http://www.bicycling.com/article/0,6...7040-1,00.html

according to this article, the findings are by Ball State University. I would hope that an accredited university uses scientific studies to base their information on. Like I said, maybe I'm incorrect on my opinions (as I say, opinions). I might also add, that I totally buy into cyclingpeaks. I really appreciate all of your insight and advice into how to train right (no pun intended) and track your progress in cycling training. So I'm not trying to "discredit" your research. I'm just questioning what I feel as a "scientific study" that apparently has 2 differing sides of the story. I ask myself which one to believe.

Since when have the analgesic effects of ibuprofen been considered "placebo effects"?????

Furthermore, a previous post has already covered the issue of kidney failure...check it out...and drinking too much water can cause problems for you too...

For me a nice long hot bath in epsom salts...works wonder! I really do not see too many issues with an advil once in a while but it does slow down recovery. I believe it has something to do with blood flow as that is how advil works.

As for aspirin I had an aunt who became a bit addicted to them and they ate away her stomach lining (??) or something like that where she had to be feed through a tube eventually.

-js

I'm not going to debate this "slow down recovery" claim...However, you will find the regular usage of NSAIDS in 99.9% (probably 100%) of US collegiate and pro football training rooms...I guess the doctors and trainers that administer to them have never read or been informed of these studies...

I think the point may be that, yes they do slow recovery. BUT, it is a trade off between pain and recovery. I'm thinking in NFL you'd take a 5% decreased recovery for 10% less pain or something of the like.

In cycling, however, recovery is king.

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The pain receptors that NSAIDs block are not the same nervous sensors that account for the "pain" (discomfort) normally associated with high intensity exercise.

The potential issue here is the combination of NSAID ingestion with prolonged/intense aerobic exercise. Thus, their safety in everyday use and/or in non-aerobic sports isn't really relevant.

Since Todd's study is as-of-yet unpublished, it is difficult to comment on their recent findings. However, given their prior research showing inhibition of protein synthesis post-exercise by these drugs, I have to wonder if the fact that the subjects were elderly, and hence potentially more prone to musculoskeletal "complaints" that may have limited their training intensity, had something to do with these results.

I'll agree to disagree with this statement. In cycling, training (riding your bike) is king. Recovery is very important but you have to perform the activity (intense training in the correct amounts) to even get to a state of needing to recover from the adaptation stimulus. Sporadic use of NSAIDS allow me to complete the number of L5 intervals for that day rather than throw in the towel from the pain. If you can complete as many Vo2 max intervals as you want on any given day without taking anything - more power to you.

The study I've read that proposes recovery is slowed was equivocal, IMO. Personally, I do not experience a slowed recovery response.

That's a nice soundbite that does not reflect my personal experience. In my own personal experience/study/what-have-you, Ibuprofen does block the pain during my intervals. I know, it's all in my head - placebo effect .

Sporadic? Or every single time you go out for an L5 session (which would better explain the defensive rigidity of your position).

If sporadic how do you know when to take them? Are your legs in agony even prior to throwing your leg over? Or do you get through one or two intervals and just say 'I cant go on the pain is tearing me apart.....must...slip...myself...NSAIDS.'? And then BOOM you transform into a fearless warrior on the war path of endless L5 intervals!

I think you need a bike fit. And the likely answer from Steve Hogg will be 'try your L5 intervals with the saddle rather than just the seatpost pushing up your ****'. That would better account for the need for NSAIDS me thinks.

So, let's say that "Vitamin I" works for you. But even if it does, is it smart? Why would you want to medicate yourself to work beyond your bodies normal pain signals? I believe the pain is there for a reason; that it's an important signal which shouldn't be ignored or suppressed. Who came up with the number of L5 intervals you have to do in a day anyway?

Also, isn't there is some risk that dependency will lead you to ever-increasing doses, or to seek out some better drug? I have an old friend who went down the route with prescription painkillers and after many years the results weren't pretty.

Note, I claim no expertise here; just thinking out loud with all the questions.

Thanks for your opinion - you are entitled to it. And everyone has one, just like your "****"hole...