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Chemo go-faster drugs! Lance, Alberto?

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  #1  
Old 08-09.-2007
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Exclamation Chemo go-faster drugs! Lance, Alberto?

PDM and Sean Kelly overdosed on EPO back in July 1991. We have come a long way since then.

Today EPO is aspirin to top cyclists and triathletes. EPO was old hat when Lance won his first Tour de France in 1999. Phamrstrong dropped EPO confessed Alex Zulle and Fernado Escartin whist on superior doping protocols and drugs.

Besides cow blood (Actovegin)
and Aranesp (EPO)
and steroids
and insulin
and corticoids

a then, little know research drug by Allos Therapeutics was in the field. RSR-13 recently branded as Efaproxiral. http://www.drugs.com/nda/rsr13_040504.html

Allos Therapeutics is in the chemo enhancement business. But take away the toxic chemo drugs and----step back. Go fast juice.

Roche Pharmaceuticals is rolling out C.E.R.A (more potent, quicker acting EPO) as an Amgen Aranesp dosing alternative.

The anti-anemia marketplace is expeted to grow to $100 BILLION someday---and not just selling into insurance policies for sick people.

The Tour de France will continue to build on its past crimes. Pro cycling is Life Science, nothing more.
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Old 08-09.-2007
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Default Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by Doctor.House
PDM and Sean Kelly overdosed on EPO back in July 1991. We have come a long way since then.

Today EPO is aspirin to top cyclists and triathletes. EPO was old hat when Lance won his first Tour de France in 1999. Phamrstrong dropped EPO confessed Alex Zulle and Fernado Escartin whist on superior doping protocols and drugs.

Besides cow blood (Actovegin)
and Aranesp (EPO)
and steroids
and insulin
and corticoids

a then, little know research drug by Allos Therapeutics was in the field. RSR-13 recently branded as Efaproxiral. http://www.drugs.com/nda/rsr13_040504.html

Allos Therapeutics is in the chemo enhancement business. But take away the toxic chemo drugs and----step back. Go fast juice.

Roche Pharmaceuticals is rolling out C.E.R.A (more potent, quicker acting EPO) as an Amgen Aranesp dosing alternative.

The anti-anemia marketplace is expeted to grow to $100 BILLION someday---and not just selling into insurance policies for sick people.

The Tour de France will continue to build on its past crimes. Pro cycling is Life Science, nothing more.
Dude I thought you left this forum...


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Old 08-09.-2007
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Default Re: Chemo go-faster drugs! Lance, Alberto?

From the article

Quote:
RSR13 (efaproxiral) is the first synthetic small molecule designed to "sensitize" hypoxic (oxygen-deprived) areas of tumors prior to radiation therapy by facilitating the release of oxygen from hemoglobin, the oxygen-carrying protein contained within red blood cells, and increasing the level of oxygen in tumors.
So, how does it work? It says RSR13 facilitates the release of oxygen in tumor cells. Does it work equally well for normal cells? What are the side effects?

Btw. the article is from May 2004. Is there any documented case of RSR13 use as a PED?


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Thumbs up Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by Cobblestones
From the article


So, how does it work? It says RSR13 facilitates the release of oxygen in tumor cells. Does it work equally well for normal cells? What are the side effects?

Btw. the article is from May 2004. Is there any documented case of RSR13 use as a PED?
Are there any documented athlete cases of:

cow blood?
human growth hormones?
Viagra?
Prozac?

RSR-13 expands 'red blood cells' by 30-50% and thins out (balloons) the membrane wall making; 1) oxygen transfer easier and/or 2) chemo doping more effective.

Thin cell wall = faster acting

Research drugs are secret---hence, you would have no clue what drugs T-Mobile may use next year.


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Old 08-09.-2007
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Default Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by Doctor.House
RSR-13 expands 'red blood cells' by 30-50% and thins out (balloons) the membrane wall making; 1) oxygen transfer easier and/or 2) chemo doping more effective.

Thin cell wall = faster acting

Research drugs are secret---hence, you would have no clue what drugs T-Mobile may use next year.
What so instead of increasing the AMOUNT of red blood cells, this stuff actually EXPANDS the effectivness of them? Am i understanding the correctly Dr.House?

So therefore, current dope tests for hematocrit level would be completely useless...?

eep. Also wouldnt thinning the membrane wall be pretty damn dangerous?

Do you think this stuff is widely used my good Doctor?


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Thumbs up Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by yeloooooo
What so instead of increasing the AMOUNT of red blood cells, this stuff actually EXPANDS the effectivness of them? Am i understanding the correctly Dr.House?

So therefore, current dope tests for hematocrit level would be completely useless...?

eep. Also wouldnt thinning the membrane wall be pretty damn dangerous?

Do you think this stuff is widely used my good Doctor?
Correctimundo my clever friend in yelooo.

Overdosing on any drug can be bad. Prozac to EPO to cortisone,

Widely used? Who can say. Lance and his LAF might know about RSR-13 and Actovegin (Norway cow blood product) too. Too bad we cannot read his Nike board of director minutes.

Maybe Craig Nichols knows?

Maybe a rogue scientist from Allos knows?

You can bet Michele Ferrari knows!


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Default Re: Chemo go-faster drugs! Lance, Alberto?

So it thins the membrane of red blood cells. Would that lead to more free hemoglobin in the bloodstream? And if so, could the increased free hemoglobin be picked up by a blood test?

ETA: and you say it expands red blood cells by 30-50%, so could it be tested for by looking at the size of red blood cells under a microscope?


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Old 08-09.-2007
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Lightbulb Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by Cobblestones
So it thins the membrane of red blood cells. Would that lead to more free hemoglobin in the bloodstream? And if so, could the increased free hemoglobin be picked up by a blood test?

ETA: and you say it expands red blood cells by 30-50%, so could it be tested for by looking at the size of red blood cells under a microscope?
I seriously doubt any WADA lab has any money to spend on blood doping.

They blew their money on Hamilton and Landis w/o much success.

In any case, RSR-13 is in use and has been for many years. Besides the Pharmstrong chemo therapy rumors----the HBOC (aka: allotropic hemoglobin modifier) was discovered by police in the 2001 San Remo Giro Hotel room raids
http://www.cyclingnews.com/results/2...un12news.shtml

Emassist (Hemassist) was also found in the athlete rooms. (X-country skiier juice)

The wonderful fraud that is drug cheating is that the fans quickly forget the history, past lies and facts. That's how Bjarne Riis & Lance Armstrong can remain employed.

btw: The RSR-13 June 12, 2001 post followed Jan Ulrich's idiotic quote that all dopers should be suspended for life.

Jan Ulrich, a true doper hypocrite.


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Default Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by Doctor.House
I seriously doubt any WADA lab has any money to spend on blood doping.

They blew their money on Hamilton and Landis w/o much success.

In any case, RSR-13 is in use and has been for many years. Besides the Pharmstrong chemo therapy rumors----the HBOC (aka: allotropic hemoglobin modifier) was discovered by police in the 2001 San Remo Giro Hotel room raids
http://www.cyclingnews.com/results/2...un12news.shtml

Emassist (Hemassist) was also found in the athlete rooms. (X-country skiier juice)

The wonderful fraud that is drug cheating is that the fans quickly forget the history, past lies and facts. That's how Bjarne Riis & Lance Armstrong can remain employed.

btw: The RSR-13 June 12, 2001 post followed Jan Ulrich's idiotic quote that all dopers should be suspended for life.

Jan Ulrich, a true doper hypocrite.
Thanks for the link, Doctor. That was hilarious. Anyway, I think I have now a better understanding of RSR-13. It makes you wonder what kind of experimental drugs are in use today, doesn't it?


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Thumbs up Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by Cobblestones
Thanks for the link, Doctor. That was hilarious. Anyway, I think I have now a better understanding of RSR-13. It makes you wonder what kind of experimental drugs are in use today, doesn't it?
In my case---yes. For those that root for Slipstream doper denial pretext cover-ups, no!

Just remember, WADA, UCI doping control DO NOT DISCOVER doping. Rather, they allow 99.9999% of the doping to pass w/o trace.

WADA serves the IOC. The IOC serves the TV Networks. The TV Networks showcase doped athletes and marketing themes to sell $300 sneakers, Viagra, watches and hearing aids.

Life science = Olympics and cycling


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Default Re: Chemo go-faster drugs! Lance, Alberto?

It's like that we love Doctor House, when he says something news with some excellent explanations.


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Default Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by poulidor
It's like that we love Doctor House, when he says something news with some excellent explanations.
Precisely. Doctor House, bring it on. What other experimental drugs have been in use, how do they work, and why aren't they detected by tests?


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Cool Re: Chemo go-faster drugs! Lance, Alberto?

Quote:
Originally Posted by Cobblestones
Precisely. Doctor House, bring it on. What other experimental drugs have been in use, how do they work, and why aren't they detected by tests?
Forget the secretive research drugs. Plenty of 15 to 30 year old drugs that still remain untested.

exogenous testosterone (unless overdosed and not protected by sponsor)

insulin/glucose
IGF-1
IGF-3

Interleukins

Viagra (Vasodiliation)

cow blood (Hemopure, Polyheme, Actovegin)

hGH, eGH

Clomid or choroinic gondatropin (female fertility hormone, leutenizing)


The war against doping is a media created theater act. Nobody is going to cease from doping, cheating or fixing TV sport outcomes.


  #14  
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Default Re: Chemo go-faster drugs! Lance, Alberto?

The bottom line is that these procedures are totally unethical! Forget about sociopaths who don't care about their bodies. How can so-called doctors morally administer these drugs? Yes, I know it's all money. It is just wrong!

I don't know about others, but I get a visceral reaction when I read these doping schedules and lists of peds. I am so vehemently opposed to drugs in my own life, so I know I am extreme. But cmon, the civil authorities really need to crack down on these doctors. Force dopers to confess and name names. The riders are at the end of the line; we need to find and SEVERLY punish the sources.

as an aside, doc, can you provide a link that discloses where laf funds are allocated. who gets these grants? what are these research facilities studying? how many of these grants fund peds and longlasting effects? is this information even available? I won't hold my breath.


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Exclamation Re: Chemo go-faster drugs! Lance, Alberto?

Pretty much everything about Lance is a lie or a zealous secret.

The Nike supported LAF is probably a fraud. It would be shocking to learn that anything good or helpful could possibly spring from such a Nike endorsed sporting fraud, filthy doping lies, rotten litigations (Walsh, Anderson, Simeoni, SCA, London Times), harrassemnt, and empty denials.

The LAF is a federal exempt charity which need not report any details to the naive public other than the obligatory IRS 990 filing----which can be deferred 9 months after the year end, and devoid of any useful footnote disclosures, grant details, or board member (insider) compensation.

Secrecy is the key. In drug research, at horse races, on Wall Street, at the NYSE and on Charitable Foundation boards. The insiders collect the finanical benefits, the public has ZERO recourse and will believe in the miracles that Lance & his media partners invent. (eg: LIVE STRONG)

Why any CF visitor would be opposed to these brutal disclosures of fraud and doping research remains a mystery to me.

Lance has NEVER been confronted with these confict-of-interest questions and his appearance as a honest anti-doper is a pitiful.

Quote:
Originally Posted by Klodifan
The bottom line is that these procedures are totally unethical! Forget about sociopaths who don't care about their bodies. How can so-called doctors morally administer these drugs? Yes, I know it's all money. It is just wrong!

I don't know about others, but I get a visceral reaction when I read these doping schedules and lists of peds. I am so vehemently opposed to drugs in my own life, so I know I am extreme. But cmon, the civil authorities really need to crack down on these doctors. Force dopers to confess and name names. The riders are at the end of the line; we need to find and SEVERLY punish the sources.

as an aside, doc, can you provide a link that discloses where laf funds are allocated. who gets these grants? what are these research facilities studying? how many of these grants fund peds and longlasting effects? is this information even available? I won't hold my breath.


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