Burley Django question

I bought a used Burley about a month ago. (I've been wanting a bent for about, oh, 20 years or so). It has sram 5.0 shifter and rear derailleur, shimano 105 crank, and a shimano sora front derailleur. Would it be possible to replace the rear derailleur with a shimano stx rear derailleur? Would it work, or would I need to use the stx shifters also. The stx is from a mountain bike. (Yes, I realize that these components aren't that great, so please give me some helpful advice.) Thanks!

The numbered SRAM stuff is ESP and is not Shimano-compatible. So the answer is, you'd also have to change the shifters. The SRAM stuff that is Shimano-compatible is named rather than numbered, i.e. Rocket, Attack, etc.

Thank you very much for your answer. Very helpful. I really appreciate it.