Here are is the Pritikin/Barnard/Ornish bibliography (not 100% complete, but representative...note
the breadth of the studies, from basic research to animal research to clinical research. All
completely consistent.
1: Roberts CK, Barnard RJ. Low-carbohydrate diets as compared with low-fat diets. N Engl J Med.
2003 Sep 4;349(10):1000-2; author reply 1000-2. No abstract available. PMID: 12959099 [PubMed
- indexed for MEDLINE]
2: Ngo TH, Barnard RJ, Cohen P, Freedland S, Tran C, deGregorio F, Elshimali YI, Heber D, Aronson
WJ. Effect of isocaloric low-fat diet on human LAPC-4 prostate cancer xenografts in severe
combined immunodeficient mice and the insulin-like growth factor axis. Clin Cancer Res. 2003
Jul;9(7):2734-43. PMID: 12855654 [PubMed - in process]
3: Barnard RJ, Ngo TH, Leung PS, Aronson WJ, Golding
LA. A low-fat diet and/or strenuous exercise alters the IGF axis in vivo and reduces prostate
tumor cell growth in vitro. Prostate. 2003 Aug 1;56(3):201-6. PMID: 12772189 [PubMed - indexed
for MEDLINE]
4: Koertge J, Weidner G, Elliott-Eller M, Scherwitz L, Merritt-Worden TA, Marlin R, Lipsenthal L,
Guarneri M, Finkel R, Saunders Jr DE, McCormac P, Scheer JM, Collins RE, Ornish D. Improvement
in medical risk factors and quality of life in women and men with coronary artery disease in
the Multicenter Lifestyle Demonstration Project. Am J Cardiol. 2003 Jun 1;91(11):1316-22. PMID:
12767423 [PubMed - indexed for MEDLINE]
5: Ngo TH, Barnard RJ, Leung PS, Cohen P, Aronson WJ. Insulin-like growth factor I (IGF-I) and IGF
binding protein-1 modulate prostate cancer cell growth and apoptosis: possible mediators for
the effects of diet and exercise on cancer cell survival. Endocrinology. 2003
Jun;144(6):2319-24. PMID: 12746292 [PubMed - indexed for MEDLINE]
6: Atkins RC, Ornish D, Wadden T. Low-carb, low-fat diet gurus face off. Interview by Joan
Stephenson. JAMA. 2003 Apr 9;289(14):1767-8, 1773. No abstract available. PMID: 12684342
[PubMed - indexed for MEDLINE]
7: Ngo TH, Barnard RJ, Tymchuk CN, Cohen P, Aronson WJ. Effect of diet and exercise on serum
insulin, IGF-I, and IGFBP-1 levels and growth of LNCaP cells in vitro (United States). Cancer
Causes Control. 2002 Dec;13(10):929-35. PMID: 12588089 [PubMed - indexed for MEDLINE]
8: Atkins RC, Sears B, Eaton B, Ornish D. Dissecting the diets. Newsweek. 2003 Jan 20;141(3):55.
No abstract available. PMID: 12545934 [PubMed - indexed for MEDLINE]
9: Barnard RJ, Aronson WJ, Tymchuk CN, Ngo TH. Prostate cancer: another aspect of the
insulin-resistance syndrome? Obes Rev. 2002 Nov;3(4):303-8. Review. PMID: 12458975 [PubMed -
indexed for MEDLINE]
10: Roberts CK, Vaziri ND, Sindhu RK, Barnard RJ. A high-fat, refined-carbohydrate diet affects
renal NO synthase protein expression and salt sensitivity. J Appl Physiol. 2003
Mar;94(3):941-6. Epub 2002 Oct 25. PMID: 12433862 [PubMed - indexed for MEDLINE]
11: Roberts CK, Vaziri ND, Barnard RJ. Effect of diet and exercise intervention on blood pressure,
insulin, oxidative stress, and nitric oxide availability. Circulation. 2002 Nov
12;106(20):2530-2. PMID: 12427646 [PubMed - indexed for MEDLINE]
12: Tymchuk CN, Barnard RJ, Ngo TH, Aronson WJ. Role of testosterone, estradiol, and insulin in
diet- and exercise-induced reductions in serum-stimulated prostate cancer cell growth in vitro.
Nutr Cancer. 2002;42(1):112-6. PMID: 12235642 [PubMed - indexed for MEDLINE]
13: Roberts CK, Berger JJ, Barnard RJ. Long-term effects of diet on leptin, energy intake, and
activity in a model of diet-induced obesity. J Appl Physiol. 2002 Sep;93(3):887-93. PMID:
12183482 [PubMed
- indexed for MEDLINE]
14: Ornish D. Dean Ornish, MD: a conversation with the editor. Interview by William Clifford
Roberts, MD. Am J Cardiol. 2002 Aug 1;90(3):271-98. No abstract available. PMID: 12127615
[PubMed - indexed for MEDLINE]
15: Molteni R, Barnard RJ, Ying Z, Roberts CK, Gomez-Pinilla F. A high-fat, refined sugar diet
reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning.
Neuroscience. 2002;112(4):803-14. PMID: 12088740 [PubMed - indexed for MEDLINE]
16: Roberts CK, Vaziri ND, Ni Z, Barnard RJ. Correction of long-term diet-induced hypertension and
nitrotyrosine accumulation by diet modification. Atherosclerosis. 2002 Aug;163(2):321-7. PMID:
12052479 [PubMed - indexed for MEDLINE]
17: Ornish D. Statins and the soul of medicine. Am J Cardiol. 2002 Jun 1;89(11):1286-90. No
abstract available. PMID: 12031729 [PubMed - indexed for MEDLINE]
18: Roberts CK, Barnard RJ, Liang KH, Vaziri ND. Effect of diet on adipose tissue and skeletal
muscle VLDL receptor and LPL: implications for obesity and hyperlipidemia. Atherosclerosis.
2002 Mar;161(1):133-41. PMID: 11882325 [PubMed - indexed for MEDLINE]
19: Dunn-Emke S, Weidner G, Ornish D. Benefits of a low-fat plant-based diet. Obes Res. 2001
Nov;9(11):731. No abstract available. PMID: 11707542 [PubMed - indexed for MEDLINE]
20: Youngren JF, Paik J, Barnard RJ. Impaired insulin-receptor autophosphorylation is an early
defect in fat-fed, insulin-resistant rats. J Appl Physiol. 2001 Nov;91(5):2240-7. PMID:
11641367 [PubMed
- indexed for MEDLINE]
21: Tymchuk CN, Tessler SB, Barnard RJ.
serum lipids in postmenopausal women on a low-fat, high-fiber diet combined with exercise. Nutr
Cancer. 2000;38(2):158-62. PMID: 11525592 [PubMed - indexed for MEDLINE]
22: Tymchuk CN, Barnard RJ, Heber D, Aronson WJ. Evidence of an inhibitory effect of diet and
exercise on prostate cancer cell growth. J Urol. 2001 Sep;166(3):1185-9. PMID: 11490320 [PubMed
- indexed for MEDLINE]
23: Roberts CK, Vaziri ND, Liang KH, Barnard RJ. Reversibility of chronic experimental syndrome X
by diet modification. Hypertension. 2001 May;37(5):1323-8. PMID: 11358948 [PubMed - indexed
for MEDLINE]
24: Ornish DM, Lee KL, Fair WR, Pettengill EB, Carroll PR. Dietary trial in prostate cancer: Early
experience and implications for clinical trial design. Urology. 2001 Apr;57(4 Suppl 1):200-1.
PMID: 11295627 [PubMed - indexed for MEDLINE]
25: Roberts CK, Vaziri ND, **** XQ, Barnard RJ. Enhanced NO inactivation and hypertension induced
by a high-fat, refined-carbohydrate diet. Hypertension. 2000 Sep;36(3):423-9. PMID: 10988276
[PubMed - indexed for MEDLINE]
26: Ornish D. High-fiber diet and colorectal adenomas. N Engl J Med. 2000 Sep 7;343(10):736; author
reply 737-8. No abstract available.
PMID: 10979768 [PubMed - indexed for MEDLINE]
27: Fonseca V, Dicker-Brown A, Ranganathan S, Song W, Barnard RJ, Fink L, Kern PA. Effects of a
high-fat-sucrose diet on enzymes in homocysteine metabolism in the rat. Metabolism. 2000
Jun;49(6):736-41. PMID: 10877198 [PubMed - indexed for MEDLINE]
28: Ornish D. Very-low fat diets. Circulation. 1999 Aug 31;100(9):1013-5. No abstract available.
PMID: 10490348 [PubMed - indexed for MEDLINE]
29: Kenney JJ, Barnard RJ, Inkeles S. Very-low-fat diets do not necessarily promote small, dense
LDL particles. Am J Clin Nutr. 1999 Sep;70(3):423-5. No abstract available. PMID: 10479209
[PubMed - indexed for MEDLINE]
30: Barnard RJ. Very-low fat diets. Circulation. 1999 Aug 31;100(9):1012-3; author reply 1014-5. No
abstract available. PMID: 10490346 [PubMed - indexed for MEDLINE]
31: Berger JJ, Barnard RJ. Effect of diet on fat cell size and hormone-sensitive lipase activity. J
Appl Physiol. 1999 Jul;87(1):227-32. PMID: 10409579 [PubMed - indexed for MEDLINE]
32: Reil TD, Barnard RJ, Kashyap VS, Roberts CK, Gelabert HA. Diet-induced changes in
endothelial-dependent relaxation of the rat aorta. J Surg Res. 1999 Jul;85(1):96-100. PMID:
10383844 [PubMed - indexed for MEDLINE]
33: Barnard RJ, Inkeles SB. Effects of an intensive diet and exercise program on lipids in
postmenopausal women. Womens Health Issues. 1999 May-Jun;9(3):155-61. PMID: 10340021 [PubMed -
indexed for MEDLINE]
34: Ornish D, Scherwitz LW, Billings JH, Brown SE, Gould KL, Merritt TA, Sparler S, Armstrong WT,
Ports TA, Kirkeeide RL, Hogeboom C, Brand RJ. Intensive lifestyle changes for reversal of
coronary heart disease. JAMA. 1998 Dec 16;280(23):2001-7. Erratum in: JAMA 1999 Apr
21;281(15):1380. PMID: 9863851 [PubMed - indexed for MEDLINE]
35: Ornish D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle
Demonstration Project. Am J Cardiol. 1998 Nov 26;82(10B):72T-76T. Review. PMID: 9860380 [PubMed
- indexed for MEDLINE]
36: Tymchuk CN, Tessler SB, Aronson WJ, Barnard RJ.
hormone-binding globulin, and prostate-specific antigen. Nutr Cancer. 1998;31(2):127-31. PMID:
9770724 [PubMed - indexed for MEDLINE]
37: Ornish D. Serum lipids after a low-fat diet. JAMA. 1998 May 6;279(17):1345-6. No abstract
available. PMID: 9582034 [PubMed - indexed for MEDLINE]
38: Barnard RJ, Roberts CK, Varon SM, Berger JJ. Diet-induced insulin resistance precedes other
aspects of the metabolic syndrome. J Appl Physiol. 1998 Apr;84(4):1311-5. PMID: 9516198 [PubMed
- indexed for MEDLINE]
39: Ornish D. Dietary fat and ischemic stroke. JAMA. 1998 Apr 15;279(15):1172; author reply 1172-3.
No abstract available. PMID: 9555749 [PubMed - indexed for MEDLINE]
40: Ornish D. Low-fat diets. N Engl J Med. 1998 Jan 8;338(2):127; author reply 128-9. No abstract
available. PMID: 9424579 [PubMed - indexed for MEDLINE]
41: Barnard RJ, DiLauro SC, Inkeles SB. Effects of intensive diet and exercise intervention in
patients taking cholesterol-lowering drugs. Am J Cardiol. 1997 Apr 15;79(8):1112-4. PMID:
9114776 [PubMed - indexed for MEDLINE]
42: Beard CM, Barnard RJ, Robbins DC, Ordovas JM, Schaefer EJ. Effects of diet and exercise on
qualitative and quantitative measures of LDL and its susceptibility to oxidation. Arterioscler
Thromb Vasc Biol. 1996 Feb;16(2):201-7. PMID: 8620333 [PubMed - indexed for MEDLINE]
43: Bagga D, Ashley JM, Geffrey SP, **** HJ, Barnard RJ, Korenman S, Heber D. Effects of a very low
fat, high fiber diet on serum hormones and menstrual function. Implications for breast cancer
prevention. Cancer. 1995 Dec 15;76(12):2491-6. PMID: 8625075 [PubMed - indexed for MEDLINE]
44: Gould KL, Ornish D, Scherwitz L, Brown S, Edens RP, Hess MJ, Mullani N, Bolomey L, Dobbs F,
Armstrong WT, et al. Changes in myocardial perfusion abnormalities by positron emission
tomography after long-term, intense risk factor modification. JAMA. 1995 Sep
20;274(11):894-901. PMID: 7674504 [PubMed - indexed for MEDLINE]
45: Czernin J, Barnard RJ, Sun KT, Krivokapich J, Nitzsche E, Dorsey D, Phelps ME, Schelbert HR.
Effect of short-term cardiovascular conditioning and low-fat diet on myocardial blood flow
and flow reserve. Circulation. 1995 Jul 15;92(2):197-204. PMID: 7600651 [PubMed - indexed
for MEDLINE]
46: Zernicke RF, Salem GJ, Barnard RJ, Schramm E. Long-term, high-fat-sucrose diet alters rat
femoral neck and vertebral morphology, bone mineral content, and mechanical properties. Bone.
1995 Jan;16(1):25-31. PMID: 7742079 [PubMed - indexed for MEDLINE]
47: Barnard RJ, Youngren JF, Martin DA. Diet, not aging, causes skeletal muscle insulin resistance.
Gerontology. 1995;41(4):205-11. PMID: 7557497 [PubMed - indexed for MEDLINE]
48: Barnard RJ, Jung T, Inkeles SB. Diet and exercise in the treatment of NIDDM. The need for early
emphasis. Diabetes Care. 1994 Dec;17(12):1469-72. PMID: 7882819 [PubMed - indexed for MEDLINE]
49: Ornish D, Denke M. Dietary treatment of hyperlipidemia. J Cardiovasc Risk. 1994 Dec;1(4):283-6.
No abstract available. PMID: 7621309 [PubMed - indexed for MEDLINE]
50: Barnard RJ, Wen SJ. Exercise and diet in the prevention and control of the metabolic syndrome.
Sports Med. 1994 Oct;18(4):218-28. Review. No abstract available. PMID: 7817062 [PubMed -
indexed for MEDLINE]
51: Ornish D, Brown SE. Treatment of and screening for hyperlipidemia. N Engl J Med. 1993 Oct
7;329(15):1124-5; author reply 1127-8. No abstract available. PMID: 8371740 [PubMed - indexed
for MEDLINE]
52: Barnard RJ, Faria DJ, Menges JE, Martin DA. Effects of a high-fat, sucrose diet on serum
insulin and related atherosclerotic risk factors in rats. Atherosclerosis. 1993
May;100(2):229-36. PMID: 8357355 [PubMed - indexed for MEDLINE]
53: Barnard RJ, Youngren JF. Regulation of glucose transport in skeletal muscle. FASEB J. 1992
Nov;6(14):3238-44. Review. PMID: 1426762 [PubMed - indexed for MEDLINE]
54: Gould KL, Ornish D, Kirkeeide R, Brown S, Stuart Y, Buchi M, Billings J, Armstrong W, Ports
T, Scherwitz
L. Improved stenosis geometry by quantitative coronary arteriography after vigorous risk factor
modification. Am J Cardiol. 1992 Apr 1;69(9):845-53. PMID: 1550011 [PubMed - indexed for MEDLINE]
55: Barnard RJ, Ugianskis EJ, Martin DA, Inkeles SB. Role of diet and exercise in the management of
hyperinsulinemia and associated atherosclerotic risk factors. Am J Cardiol. 1992 Feb
15;69(5):440-4. PMID: 1736602 [PubMed - indexed for MEDLINE]
56: Salem GJ, Zernicke RF, Barnard RJ. Diet-related changes in mechanical properties of rat
vertebrae. Am J Physiol. 1992 Feb;262(2 Pt 2):R318-21. PMID: 1539741 [PubMed - indexed
for MEDLINE]
57: Ornish D. What if Americans ate less fat? JAMA. 1992 Jan 15;267(3):362; author reply 363-4. No
abstract available. PMID: 1727949 [PubMed - indexed for MEDLINE]
58: Barnard RJ. Effects of life-style modification on serum lipids. Arch Intern Med. 1991
Jul;151(7):1389-94. PMID: 2064490 [PubMed - indexed for MEDLINE]
59: Heber D, Ashley JM, Leaf DA, Barnard RJ. Reduction of serum estradiol in postmenopausal women
given free access to low-fat high-carbohydrate diet. Nutrition. 1991 Mar-Apr;7(2):137-9;
discussion 139-40. PMID: 1666318 [PubMed - indexed for MEDLINE]
60: Ornish D. Reversing heart disease through diet, exercise, and stress management: an interview
with Dean Ornish. Interview by Elaine R Monsen. J Am Diet Assoc. 1991 Feb;91(2):162-5. No
abstract available. PMID: 1991929 [PubMed - indexed for MEDLINE]
61: Li KC, Zernicke RF, Barnard RJ, Li AF. Effects of a high fat-sucrose diet on cortical bone
morphology and biomechanics. Calcif Tissue Int. 1990 Nov;47(5):308-13. PMID: 2257525 [PubMed -
indexed for MEDLINE]
62: Barnard RJ. Short-term reductions in serum lipids through diet and exercise. N Engl J Med. 1990
Oct 18;323(16):1142-3. No abstract available. PMID: 2215586 [PubMed - indexed for MEDLINE]
63: Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, Ports TA, McLanahan SM, Kirkeeide
RL, Brand RJ, Gould KL. Lifestyle changes and heart disease. Lancet. 1990 Sep
22;336(8717):741-2. No abstract available. PMID: 1975906 [PubMed - indexed for MEDLINE]
64: Mehrabian M, Peter JB, Barnard RJ, Lusis AJ. Dietary regulation of fibrinolytic factors.
Atherosclerosis. 1990 Sep;84(1):25-32. PMID: 2147372 [PubMed - indexed for MEDLINE]
65: Ornish D, Brown SE, Scherwitz LW, Billings JH, Armstrong WT, Ports TA, McLanahan SM, Kirkeeide
RL, Brand RJ, Gould KL. Can lifestyle changes reverse coronary heart disease? The Lifestyle
Heart Trial. Lancet. 1990 Jul 21;336(8708):129-33. PMID: 1973470 [PubMed - indexed for MEDLINE]
66: Reddy BS, Engle A, Simi B, O'Brien LT, Barnard RJ, Pritikin N, Wynder EL. Effect of low-fat,
high-carbohydrate, high-fiber diet on fecal bile acids and neutral sterols. Prev Med. 1988
Jul;17(4):432-9. PMID: 2851138 [PubMed - indexed for MEDLINE]
67: Grimditch GK, Barnard RJ, Hendricks L, Weitzman D.
Peripheral insulin sensitivity as modified by diet and exercise training. Am J Clin Nutr. 1988
Jul;48(1):38-43. PMID: 2839027 [PubMed - indexed for MEDLINE]
68: Grimditch GK, Barnard RJ, Sternlicht E, Whitson RH, Kaplan SA. Effect of diet on insulin
binding and glucose transport in rat sarcolemmal vesicles. Am J Physiol. 1987 Mar;252(3 Pt
1):E420-5. PMID: 3548433 [PubMed - indexed for MEDLINE]
69: Barnard RJ, Hall JA, Chaudhari A, Miller JE, Kirschenbaum MA. Effects of a low-fat,
low-cholesterol diet on serum lipids, platelet aggregation and thromboxane formation.
Prostaglandins Leukot Med. 1987 Mar;26(3):241-52. PMID: 3472254 [PubMed - indexed for MEDLINE]
70: Grimditch GK, Barnard RJ, Kaplan SA, Sternlicht E.
Effect of training on insulin binding to rat skeletal muscle sarcolemmal vesicles. Am J Physiol.
1986 May;250(5 Pt 1):E570-5. PMID: 3518488 [PubMed - indexed for MEDLINE]
71: Holly RG, Barnard RJ, Rosenthal M, Applegate E, Pritikin N. Triathlete characterization and
response to prolonged strenuous competition. Med Sci Sports Exerc. 1986 Feb;18(1):123-7. PMID:
3959855 [PubMed - indexed for MEDLINE]
72: Sacks FM, Ornish D, Rosner B, McLanahan S, Castelli WP, Kass EH. Plasma lipoprotein levels in
vegetarians. The effect of ingestion of fats from dairy products. JAMA. 1985 Sep
13;254(10):1337-41. PMID: 4021011 [PubMed - indexed for MEDLINE]
73: Hubbard JD, Inkeles S, Barnard RJ. Nathan Pritikin's heart. N Engl J Med. 1985 Jul 4;313(1):52.
No abstract available. PMID: 3889648 [PubMed - indexed for MEDLINE]
74: Rosenthal MB, Barnard RJ, Rose DP, Inkeles S, Hall J, Pritikin N. Effects of a
high-complex-carbohydrate, low-fat, low-cholesterol diet on levels of serum lipids and
estradiol. Am J Med. 1985 Jan;78(1):23-7. PMID: 3966484 [PubMed - indexed for MEDLINE]
75: Barnard RJ, Massey MR, Cherny S, O'Brien LT, Pritikin N. Long-term use of a
high-complex-carbohydrate, high-fiber, low-fat diet and exercise in the treatment of NIDDM
patients. Diabetes Care. 1983 May-Jun;6(3):268-73. PMID: 6307614 [PubMed - indexed for MEDLINE]
76: Weber F, Barnard RJ, Roy D. Effects of a high-complex-carbohydrate, low-fat diet and daily
exercise on individuals 70 years of age and older. J Gerontol. 1983 Mar;38(2):155-61. PMID:
6827033 [PubMed - indexed for MEDLINE]
77: Ornish D, Scherwitz LW, Doody RS, Kesten D, McLanahan SM, Brown SE, DePuey E, Sonnemaker R,
Haynes C, Lester J, McAllister GK, Hall RJ, Burdine JA, Gotto AM Jr. Effects of stress
management training and dietary changes in treating ischemic heart disease. JAMA. 1983 Jan
7;249(1):54-9. PMID: 6336794 [PubMed - indexed for MEDLINE]
78: Barnard RJ, Lattimore L, Holly RG, Cherny S, Pritikin N. Response of non-insulin-dependent
diabetic patients to an intensive program of diet and exercise. Diabetes Care. 1982
Jul-Aug;5(4):370-4. PMID: 7151652 [PubMed - indexed for MEDLINE]