A
Archimedes Plut
Guest
I am massively revising my website of
www.iw.net/~a_plutonium because it is written in a textbook
fashion that it requires massive editing and deleting and
adding onto about every 5 years. I have neglected this
website for about 10 years and so I have a big job ahead of
me. My other website of www.archimedesplutonium.com needs
no periodic editing because it is structured as a archive
that I merely collect the posts I post and enter or dump it
into the website. Archiving does not require editing
because it wants to save everything whether correct or
riddled with error.
Files 150 and 151 deal with Alzheimers Huntington and Prion
disease. I was fortunate to have a running dialogue and
conversation with at least 3 scientists from Berkeley and
Cambridge Univ about these diseases starting with the year
1997 and specifically these dates:
Oct-Nov 1997 Dec 1998 Feb-Mar 1999 Jan 2004 anyone
interested in that long history can view it at
www.archimedesplutonium.com website
I must have had over 2,000 posts to the internet in
conversations with 3 or more scientists about these
diseases. And my old practice of filling File150 and File151
with many of those past posts. That practice must cease
because my archived website handles all of those posts and
no need to repeat those posts in this textbook website where
I want to achieve understanding and clarity.
So that means I have to toss out old posts from this website
and to attempt to keep it current.
Let me just remark on the history of Alzheimers, Huntington,
and Prion. I dived into these 3 diseases back in October of
1997 noting the analogy similarity of a ant disease in the
tropics where a fungus infects an ant's brain and kills the
ant. I could not escape the notice of a analogy between
fungus ant disease and Prion disease. It then migrated theory-
wise to thinking that Prion disease is the analogy to sickle
cell anemia disease only with a deformed brain protein
instead of red blood cells. It migrated into many other
theories and hypothesis but then recently is news not of
Prion disease with metal-ions from phosmet and magnetic
manganese but news from Alzheimers in that the plaque
buildup (much like prion buildup) is caused by a scissors
that wrongly snips the APP protein into 2 segments wherein
the one segment ends up being toxic Alzheimers plaques.
So, is there a similar scissors mechanism or scissors-like
mechanism that causes Prion disease?
So I left the discussion of Alzheimers, Huntington, Prion
just January of 2004 with the open issue of a Scissors
mechanism for Alzheimers and whether Huntington and Prion
also have a scissors mechanism and whether magnetic
manganese is the metal ion culprit that causes Prion disease
and whether Huntington and Alzheimers also have a metal-ion
facilitator culprit.
One of the issues I stressed and harped and harped on from
1997 to present day is that the Nobel prize to Prusiner for
his Prion theory was a prize that was a huge mistake and
that it was perhaps 20 years too soon. To have given the
Nobel to Prusiner was so premature, that the Nobel should
have given a prize to any lead researcher of Alzheimers
circa 1995 to 1997 and to have given a prize to any lead
researcher for Huntington's disease circa 1995-1997. The
reason the Nobel Committee never awarded Alzheimers or
Huntington from 1990-2003 was because the mechanism for
Alzheimers and Huntington are still not understood. Prion is
not understand even to this very day, yet the Nobel
Committee blustered and rammed ahead giving a prize out for
Prion disease when it never should have. The Nobel to
Prusiner is one of the worst Nobel awards ever given. The
Nobel Committee in giving Prusiner the award were more
rambunctious and impetuous than Mr. Bush wanting to invade
Iraq in 2003. In fact, it can be argued that Mr. Bush had
more grounds to invade Iraq than the Nobel Committee had
grounds to award Mr. Prusiner the prize for his work on
Prion disease. And it is ironic that Mr. Blix is from Sweden
where the Nobel Committee is and that Mr. Blix is laying it
straight as far as the groundless claims of Weapons of Mass
Destruction.
One other item I want to mention for Files 150 and 151 is
that in that history of 1997 on Prion disease, is that I
attacked the Prusiner Model on two grounds and it is these
two grounds which convinced me back in 1995-March2004 that
the Prusiner Model is a complete fake.
(1) Thermodynamically it is impossible for a bad-prion-
molecule to turn a good-prion-molecule into an identical
copy. The energy equation does not give enough energy
for a similar protein to alter a different protein into
a identical copy. Just not enough energy.
(2) If prion proteins really did what the Prusiner Model
says then the lowest form of life is not the cell but
proteins like prion-proteins because replication or
reproduction is the main distinguishing characteristic
of life. And the Prusiner Model is that a protein thence
becomes the lowest form of life and makes the cell and
DNA as excess baggage.
On those two ground above convinced me that the Prusiner
Model was a fake and that it is only a matter of time before
the true mechanism of how Prion disease and how Huntington
and Alzheimers work.
Also I need to note that I suspect that Prion, Huntington
and Alzheimers are different but that they are very much
alike in several similarities. So that a mechanism of how
each works may have a family resemblance. Such that if metal-
ions plays a key role in Prion disease it is likely that metal-
ions plays a role in Huntington and Alzheimers and likewise
for the scissors mechanism in Alzheimers probably has a
scissors mechanism to be found in Huntington and Prion.
I believe these 3 diseases are related more than they are
not related.
Archimedes Plutonium whole entire Universe is just one big
atom where dots of the electron-dot-cloud are galaxies
(www.iw.net/~a_plutonium) website of the science of AP under
revision what used to be my old science website
www.newphys.se/elektromagnum/physics/LudwigPlutonium from
years 1993 to 2004
www.iw.net/~a_plutonium because it is written in a textbook
fashion that it requires massive editing and deleting and
adding onto about every 5 years. I have neglected this
website for about 10 years and so I have a big job ahead of
me. My other website of www.archimedesplutonium.com needs
no periodic editing because it is structured as a archive
that I merely collect the posts I post and enter or dump it
into the website. Archiving does not require editing
because it wants to save everything whether correct or
riddled with error.
Files 150 and 151 deal with Alzheimers Huntington and Prion
disease. I was fortunate to have a running dialogue and
conversation with at least 3 scientists from Berkeley and
Cambridge Univ about these diseases starting with the year
1997 and specifically these dates:
Oct-Nov 1997 Dec 1998 Feb-Mar 1999 Jan 2004 anyone
interested in that long history can view it at
www.archimedesplutonium.com website
I must have had over 2,000 posts to the internet in
conversations with 3 or more scientists about these
diseases. And my old practice of filling File150 and File151
with many of those past posts. That practice must cease
because my archived website handles all of those posts and
no need to repeat those posts in this textbook website where
I want to achieve understanding and clarity.
So that means I have to toss out old posts from this website
and to attempt to keep it current.
Let me just remark on the history of Alzheimers, Huntington,
and Prion. I dived into these 3 diseases back in October of
1997 noting the analogy similarity of a ant disease in the
tropics where a fungus infects an ant's brain and kills the
ant. I could not escape the notice of a analogy between
fungus ant disease and Prion disease. It then migrated theory-
wise to thinking that Prion disease is the analogy to sickle
cell anemia disease only with a deformed brain protein
instead of red blood cells. It migrated into many other
theories and hypothesis but then recently is news not of
Prion disease with metal-ions from phosmet and magnetic
manganese but news from Alzheimers in that the plaque
buildup (much like prion buildup) is caused by a scissors
that wrongly snips the APP protein into 2 segments wherein
the one segment ends up being toxic Alzheimers plaques.
So, is there a similar scissors mechanism or scissors-like
mechanism that causes Prion disease?
So I left the discussion of Alzheimers, Huntington, Prion
just January of 2004 with the open issue of a Scissors
mechanism for Alzheimers and whether Huntington and Prion
also have a scissors mechanism and whether magnetic
manganese is the metal ion culprit that causes Prion disease
and whether Huntington and Alzheimers also have a metal-ion
facilitator culprit.
One of the issues I stressed and harped and harped on from
1997 to present day is that the Nobel prize to Prusiner for
his Prion theory was a prize that was a huge mistake and
that it was perhaps 20 years too soon. To have given the
Nobel to Prusiner was so premature, that the Nobel should
have given a prize to any lead researcher of Alzheimers
circa 1995 to 1997 and to have given a prize to any lead
researcher for Huntington's disease circa 1995-1997. The
reason the Nobel Committee never awarded Alzheimers or
Huntington from 1990-2003 was because the mechanism for
Alzheimers and Huntington are still not understood. Prion is
not understand even to this very day, yet the Nobel
Committee blustered and rammed ahead giving a prize out for
Prion disease when it never should have. The Nobel to
Prusiner is one of the worst Nobel awards ever given. The
Nobel Committee in giving Prusiner the award were more
rambunctious and impetuous than Mr. Bush wanting to invade
Iraq in 2003. In fact, it can be argued that Mr. Bush had
more grounds to invade Iraq than the Nobel Committee had
grounds to award Mr. Prusiner the prize for his work on
Prion disease. And it is ironic that Mr. Blix is from Sweden
where the Nobel Committee is and that Mr. Blix is laying it
straight as far as the groundless claims of Weapons of Mass
Destruction.
One other item I want to mention for Files 150 and 151 is
that in that history of 1997 on Prion disease, is that I
attacked the Prusiner Model on two grounds and it is these
two grounds which convinced me back in 1995-March2004 that
the Prusiner Model is a complete fake.
(1) Thermodynamically it is impossible for a bad-prion-
molecule to turn a good-prion-molecule into an identical
copy. The energy equation does not give enough energy
for a similar protein to alter a different protein into
a identical copy. Just not enough energy.
(2) If prion proteins really did what the Prusiner Model
says then the lowest form of life is not the cell but
proteins like prion-proteins because replication or
reproduction is the main distinguishing characteristic
of life. And the Prusiner Model is that a protein thence
becomes the lowest form of life and makes the cell and
DNA as excess baggage.
On those two ground above convinced me that the Prusiner
Model was a fake and that it is only a matter of time before
the true mechanism of how Prion disease and how Huntington
and Alzheimers work.
Also I need to note that I suspect that Prion, Huntington
and Alzheimers are different but that they are very much
alike in several similarities. So that a mechanism of how
each works may have a family resemblance. Such that if metal-
ions plays a key role in Prion disease it is likely that metal-
ions plays a role in Huntington and Alzheimers and likewise
for the scissors mechanism in Alzheimers probably has a
scissors mechanism to be found in Huntington and Prion.
I believe these 3 diseases are related more than they are
not related.
Archimedes Plutonium whole entire Universe is just one big
atom where dots of the electron-dot-cloud are galaxies
(www.iw.net/~a_plutonium) website of the science of AP under
revision what used to be my old science website
www.newphys.se/elektromagnum/physics/LudwigPlutonium from
years 1993 to 2004