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Eur Arch Psychiatry Clin Neurosci. 2004 Jun;254(3):143-147.
Related Articles, Links
Increased oxidative stress and altered activities of
erythrocyte free radical scavenging enzymes in autism.
Zoroglu SS, Armutcu F, Ozen S, Gurel A, Sivasli E, Yetkin
O, Meram I.
Gaziantep Typ Fakultesi, Kolejtepe Binasi Cocuk ve Ergen
Psikiyatrisi AD, Kolejtepe, 27200, Gaziantep, Turkey,
[email protected]
There is great evidence in recent years that oxygen free
radicals play an important role in the pathophysiology of
many neuropsychiatric disorders. The present study was
performed to assess the changes in red blood cells
thiobarbituric acid-reactive substances (TBARS) levels, and
superoxide dismutase (SOD), catalase (CAT), adenosine
deaminase (ADA) and xanthine oxidase
(XO) activities in patients with autism (n = 27) compared
to age- and
levels (p < 0.001) and XO (p < 0.001) and SOD (p < 0.001)
activity, decreased CAT (p < 0.001) activity and unchanged
ADA activity were detected. It is proposed that antioxidant
status may be changed in autism and this new situation may
induce lipid peroxidation. These findings indicated a
possible role of increased oxidative stress and altered
enzymatic antioxidants, both of which may be relevant to the
pathophysiology of autism.
PMID: 15205966 [PubMed - as supplied by publisher]
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Who loves ya. Tom Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
PEOPLE WALKING
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Related Articles, Links
Increased oxidative stress and altered activities of
erythrocyte free radical scavenging enzymes in autism.
Zoroglu SS, Armutcu F, Ozen S, Gurel A, Sivasli E, Yetkin
O, Meram I.
Gaziantep Typ Fakultesi, Kolejtepe Binasi Cocuk ve Ergen
Psikiyatrisi AD, Kolejtepe, 27200, Gaziantep, Turkey,
[email protected]
There is great evidence in recent years that oxygen free
radicals play an important role in the pathophysiology of
many neuropsychiatric disorders. The present study was
performed to assess the changes in red blood cells
thiobarbituric acid-reactive substances (TBARS) levels, and
superoxide dismutase (SOD), catalase (CAT), adenosine
deaminase (ADA) and xanthine oxidase
(XO) activities in patients with autism (n = 27) compared
to age- and
levels (p < 0.001) and XO (p < 0.001) and SOD (p < 0.001)
activity, decreased CAT (p < 0.001) activity and unchanged
ADA activity were detected. It is proposed that antioxidant
status may be changed in autism and this new situation may
induce lipid peroxidation. These findings indicated a
possible role of increased oxidative stress and altered
enzymatic antioxidants, both of which may be relevant to the
pathophysiology of autism.
PMID: 15205966 [PubMed - as supplied by publisher]
------------------------------------------------------------
--------------
------
Who loves ya. Tom Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking