Okay, now you're talking. Sounds like you are even more suceptible to
oxidized cholesterol than most people (see the study I copied and
pasted below). You need to be really careful. Full fat dairy should
be fine, just stay away from homogenized stuff and also products with
carrageenan in them, but try to buy organic. Iron is a real problem in
terms of oxidized cholesterol, so "red meat" is especially bad, and if
you were my patient, I would tell you to avoid unsaturated fats
completely. Go with unrefined coconut oil. I personally like Coconut
Oil Supreme, which I get over the internet, but there are other brands
that should be just as good, and you can do a google search to find the
cheapest, if that's a concern. Only boil eggs. Do not use foods that
have a lot of cholesterol in high heat cooking. If you use butter,
which isn't bad, use it as is - do not heat it. You need to worry
about the foods you eat, how you cook them, and the iron content
(copper is also a potential problem, so keep copper consumption at
reasonable levels).
J Atheroscler Thromb. 2004;11(3):167-72. Related Articles,Links
Enhanced susceptibility of LDL to oxidative modification in a CTX
patient:- role of chenodeoxycholic acid in xanthoma formation.
Kinoshita M, Kawamura M, Fujita M, Hirota D, Suda T, Taki M, Kusano J,
Takao K, Takenaka H, Kubota S, Teramoto T.
Department of Internal Medicine, Teikyo University School of Medicine,
Tokyo, Japan.
[email protected]
Cerebrotendinous xanthomatosis (CTX) is a rare familial sterol storage
disease, causing multiple xanthomas in tendons and the brain. The
underlying biochemical defect is a lack of the hepatic mitochondrial
cholesterol 27-hydroxylase involved in the normal biosynthesis of bile
acid, resulting in reduced biosynthesis of chenodeoxycholic acid
(CDCA). It has been reported that administration of CDCA to CTX
patients improves neurological disorders and xanthomas of the Achilles
tendon. The present study investigated the effect of CDCA on the
mechanism of cholesterol accumulation in macrophages, the major cells
in xanthoma. The LDL from the patients in this study was significantly
more susceptible to oxidative modification than normal LDL, and
supplement therapy with CDCA resulted in an improvement in the
susceptibility to oxidative modification. In the incubation of CDCA
with plasma, 13% of the CDCA added to serum was recovered in the LDL
fraction. In addition, supplementation with CDCA enhanced cholesteryl
ester transfer protein (CETP) activity and reduced
high-density-lipoprotein cholesterol levels in the plasma. This
evidence suggests that the multiple xanthomas observed in CTX may be
induced by increased oxidized LDL and the low activity of CETP, both of
which are caused by a lack of CDCA.