Alzheimer's prevention diet: comment on this family's strategies?



M

Matt

Guest
Hello,

My aunt has compiled the following "rules of thumb" that my family
uses for our Alzheimer's prevention diet. Can anyone comment on these
points and/or possibly point to other places of reference so that we
can possibly learn more, maybe read about other perspectives/opinions
on Alzheimer's prevention with diet? Are there other steps we might
take above and beyond what is listed below?

(My grandmother and great-grandmother have experienced Alzheimer's, so
my family is quite sensitive and aware of any reasonable prevention
measures that we can take.)

-Matt

[[ My aunt's compilation follows... ]]

I've listed my prevention strategies in order of my perceived
importance. These are not proven to inhibit the disease, but they are
good health practices anyway….so what do you have to lose?

1. Choline - This amino acid improves neuro-transmission in the
memory portion of the brain. One of the reason that Grandma took the
drug Aricept was to increase the choline production in the brain.

Choline can be found in eggs, green leafy vegetables, legumes, and
tofu. You can also by it in capsule form. There is no set daily
dosage requirement.

2. Vitamin E - A powerful anti-oxidant believed to be the most
important of all vitamins in preventing Alzheimer's. Most research
supports taking well above the daily recommended dosage. I take 1,000
mg. twice a day.

3. Vitamin C - Useful in the development of new brain cells which
slows down at the onset of Alzheimer's. Again research suggests a
higher than normal dosage. I take 1,000 mg. three times a day.

4. Fish oils - Omega 3 fatty acids are rich in fish oils. The
highest dosage is found in sardines, salmon, tuna and turbot. You
should be having a minimum of two servings per week. I take an fatty
acid supplement three times a day that contains both Omega 3 and 6.
Not only has it been found to improve brain efficiency, but it also
maintains good joint health and helps guard cholesterol levels.

5. Homocysteine level in Blood - The higher the level of
homocysteine, the more likely you are to develop the disease.
Homocysteines has a toxic effect on brain cells that can begin to age
the brain long before Alzheimer's sets in. A blood test can tell you
if your levels are elevated. Take 2 mg. of folic acid to keep them
under control. This is more than typically found in your daily
multivitamin.

6. Aluminum - Avoid ingesting it. Aluminum shows up in the
autopsies of Alzheimer's victims' brains. There toxic properties may
contribute to the destruction of brain cells. Minimize your use of
soda cans and aluminum cook ware. Watch for traces of harmful metals
in your antacid and other over-the-counter drugs.

7. Ibuprofen - This in the most controversial of the
recommendations I am making to you. This is because regular use of
Important may lead to liver and kidney damage, as well as irritate
your stomach lining. Nonetheless, inflammation is also believed to
play a big factor in Alzheimer's. The swelling of the brain membranes
is believed to play a part in the development of amyloid plaques in
the brain.

I take one 200 mg. tablet twice a day for several months, then
alternate its use with an herbal supplement alternative. It is called
Zyflamend from New Chapter. The herb is not only unproven, but more
expensive than taking Advil. It is much fewer side effects, however.

8. Deep breathing - Oxygen to the brain is critically important
to normal reticular activity that keeps your brain alert. Aerobic
exercise, yoga or pilates are great ways to meet this need.

9. Water - Dehydration effects proper brain function, and most of
us walk around in this condition every day without even realizing it.
I keep a water bottle with me almost everywhere I go and drink one
full bottle first thing every morning.

Hope this helps. For more information you may log onto the
Alzheimer's website at www.ALZ.org. The is some incredibly promising
research out there using passive immunization of Beta Amyloids that
are believed to be the primary cause of the disease. There are also a
new advances in slowing down the disease through stimulation of nerve
growth factors in the brain. Not much can be done at present until
symptoms arise in the victim. Many researchers believe that the
damage begins in the brain up to 20 years before these symptoms first
occur. For this reason, it is none to soon for each of you to take a
pro-active stance in your own personal prevention of the disease. I
already give [my children that are 11 and 14] extra E and C and a
choline supplement. They seldom drink soda or other canned drinks and
I try to push the water as much as I can. I just can't see a down
side to forming good habits now.
--
Remove the obvious text (including the dash) to email me.
 
Matt:

I have been under the care of my neurologist for nearly three years now for
Early Onset Alzheimer's Disease. I am 54 years old and I think that I have
had every test known to man for my condition. For the last year, my doctors
have had me on a regimen of the following:

Reminyl 12 mg twice daily
Vitamin E 1000 mg twice daily
Vitamin C 1000 mg twice daily
Ibuprofen (Advil) 500 mg nightly

On my own I take (but they do not object), the following:

Shark's Liver Oil gel capsules found at GNC

I drink at least two (2) bottles of tonic water a day for leg cramps for the
quinine in it. My doctors advises that quinine tablets were too much but
tonic water was much better. Plus, I drink lots of water.

I keep my brain very active by doing plenty of puzzles daily and trying to
learn something new every day. I walk daily even when I really don't want
to get out.

During the last three months, I have seen a considerable improvement in my
condition. Where I would not leave the house unaccompanied by one of my
family members, I am now driving again. I am remembering things even my
husband is forgetting.

I am due for another MRI and tests this month and, hopefully, it will not
show near the amount of brain atrophy that it did last year. Maybe this
regimen does work but only time will tell. I am thankful for the time being
that it is working for me, and that it has given me somemore time to enjoy
my family.

Kathy


"Matt" <[email protected]> wrote in message
news:[email protected]...
> Hello,
>
> My aunt has compiled the following "rules of thumb" that my family
> uses for our Alzheimer's prevention diet. Can anyone comment on these
> points and/or possibly point to other places of reference so that we
> can possibly learn more, maybe read about other perspectives/opinions
> on Alzheimer's prevention with diet? Are there other steps we might
> take above and beyond what is listed below?
>
> (My grandmother and great-grandmother have experienced Alzheimer's, so
> my family is quite sensitive and aware of any reasonable prevention
> measures that we can take.)
>
> -Matt
>
> [[ My aunt's compilation follows... ]]
>
> I've listed my prevention strategies in order of my perceived
> importance. These are not proven to inhibit the disease, but they are
> good health practices anyway..so what do you have to lose?
>
> 1. Choline - This amino acid improves neuro-transmission in the
> memory portion of the brain. One of the reason that Grandma took the
> drug Aricept was to increase the choline production in the brain.
>
> Choline can be found in eggs, green leafy vegetables, legumes, and
> tofu. You can also by it in capsule form. There is no set daily
> dosage requirement.
>
> 2. Vitamin E - A powerful anti-oxidant believed to be the most
> important of all vitamins in preventing Alzheimer's. Most research
> supports taking well above the daily recommended dosage. I take 1,000
> mg. twice a day.
>
> 3. Vitamin C - Useful in the development of new brain cells which
> slows down at the onset of Alzheimer's. Again research suggests a
> higher than normal dosage. I take 1,000 mg. three times a day.
>
> 4. Fish oils - Omega 3 fatty acids are rich in fish oils. The
> highest dosage is found in sardines, salmon, tuna and turbot. You
> should be having a minimum of two servings per week. I take an fatty
> acid supplement three times a day that contains both Omega 3 and 6.
> Not only has it been found to improve brain efficiency, but it also
> maintains good joint health and helps guard cholesterol levels.
>
> 5. Homocysteine level in Blood - The higher the level of
> homocysteine, the more likely you are to develop the disease.
> Homocysteines has a toxic effect on brain cells that can begin to age
> the brain long before Alzheimer's sets in. A blood test can tell you
> if your levels are elevated. Take 2 mg. of folic acid to keep them
> under control. This is more than typically found in your daily
> multivitamin.
>
> 6. Aluminum - Avoid ingesting it. Aluminum shows up in the
> autopsies of Alzheimer's victims' brains. There toxic properties may
> contribute to the destruction of brain cells. Minimize your use of
> soda cans and aluminum cook ware. Watch for traces of harmful metals
> in your antacid and other over-the-counter drugs.
>
> 7. Ibuprofen - This in the most controversial of the
> recommendations I am making to you. This is because regular use of
> Important may lead to liver and kidney damage, as well as irritate
> your stomach lining. Nonetheless, inflammation is also believed to
> play a big factor in Alzheimer's. The swelling of the brain membranes
> is believed to play a part in the development of amyloid plaques in
> the brain.
>
> I take one 200 mg. tablet twice a day for several months, then
> alternate its use with an herbal supplement alternative. It is called
> Zyflamend from New Chapter. The herb is not only unproven, but more
> expensive than taking Advil. It is much fewer side effects, however.
>
> 8. Deep breathing - Oxygen to the brain is critically important
> to normal reticular activity that keeps your brain alert. Aerobic
> exercise, yoga or pilates are great ways to meet this need.
>
> 9. Water - Dehydration effects proper brain function, and most of
> us walk around in this condition every day without even realizing it.
> I keep a water bottle with me almost everywhere I go and drink one
> full bottle first thing every morning.
>
> Hope this helps. For more information you may log onto the
> Alzheimer's website at www.ALZ.org. The is some incredibly promising
> research out there using passive immunization of Beta Amyloids that
> are believed to be the primary cause of the disease. There are also a
> new advances in slowing down the disease through stimulation of nerve
> growth factors in the brain. Not much can be done at present until
> symptoms arise in the victim. Many researchers believe that the
> damage begins in the brain up to 20 years before these symptoms first
> occur. For this reason, it is none to soon for each of you to take a
> pro-active stance in your own personal prevention of the disease. I
> already give [my children that are 11 and 14] extra E and C and a
> choline supplement. They seldom drink soda or other canned drinks and
> I try to push the water as much as I can. I just can't see a down
> side to forming good habits now.
> --
> Remove the obvious text (including the dash) to email me.
 
Mon, 02 Feb 2004 01:05:49 GMT in article
<[email protected]> Matt
<[email protected]> wrote:

>Hello,
>
>My aunt has compiled the following "rules of thumb" that my family
>uses for our Alzheimer's prevention diet. Can anyone comment on these
>points and/or possibly point to other places of reference so that we
>can possibly learn more, maybe read about other perspectives/opinions
>on Alzheimer's prevention with diet? Are there other steps we might
>take above and beyond what is listed below?
>
>(My grandmother and great-grandmother have experienced Alzheimer's, so
>my family is quite sensitive and aware of any reasonable prevention
>measures that we can take.)
>
>-Matt
>
>[[ My aunt's compilation follows... ]]
>

There are some interesting studies about Salvia lavandulaefolia (Spanish
Sage). And what's the current status of Ginkgo biloba?. I know that the
results of the trials have been conflicting since the early successes, but
perhaps it may be worth trying together with other supplements. Some other
supplements possibly worth considering: acetyl-L-carnitine, alpha-lipoic
acid, phosphatidylserine and melatonin.



--
Matti Narkia
 
Mon, 02 Feb 2004 04:09:57 +0200 in article
<[email protected]> Matti Narkia
<[email protected]> wrote:

>Mon, 02 Feb 2004 01:05:49 GMT in article
><[email protected]> Matt
><[email protected]> wrote:
>
>>Hello,
>>
>>My aunt has compiled the following "rules of thumb" that my family
>>uses for our Alzheimer's prevention diet. Can anyone comment on these
>>points and/or possibly point to other places of reference so that we
>>can possibly learn more, maybe read about other perspectives/opinions
>>on Alzheimer's prevention with diet? Are there other steps we might
>>take above and beyond what is listed below?
>>
>>(My grandmother and great-grandmother have experienced Alzheimer's, so
>>my family is quite sensitive and aware of any reasonable prevention
>>measures that we can take.)
>>
>>-Matt
>>
>>[[ My aunt's compilation follows... ]]
>>

>There are some interesting studies about Salvia lavandulaefolia (Spanish
>Sage). And what's the current status of Ginkgo biloba?. I know that the
>results of the trials have been conflicting since the early successes, but
>perhaps it may be worth trying together with other supplements. Some other
>supplements possibly worth considering: acetyl-L-carnitine, alpha-lipoic
>acid, phosphatidylserine and melatonin.


Perhaps also curcumin and some other substances from Curcuma longa.

--
Matti Narkia
 
Matti Narkia wrote...

> >[[ My aunt's compilation follows... ]]
> >

> There are some interesting studies about Salvia lavandulaefolia (Spanish
> Sage). And what's the current status of Ginkgo biloba?. I know that the
> results of the trials have been conflicting since the early successes, but
> perhaps it may be worth trying together with other supplements. Some other
> supplements possibly worth considering: acetyl-L-carnitine, alpha-lipoic
> acid, phosphatidylserine and melatonin.


I'm surprised not to see B12 (as methylcobalamin, 500-1500 micrograms per
day) and betaine. B12 works well with folic acid to reduce homocysteine, and
betaine has been shown to reduce homocysteine dramatically.

--
John de Hoog
http://dehoog.org
 
On Mon, 02 Feb 2004 01:05:49 GMT, Matt
<[email protected]> wrote:
>
>My aunt has compiled the following "rules of thumb" that my family
>uses for our Alzheimer's prevention diet. Can anyone comment on these
>points and/or possibly point to other places of reference so that we
>can possibly learn more, maybe read about other perspectives/opinions
>on Alzheimer's prevention with diet? Are there other steps we might
>take above and beyond what is listed below?
>


Have you had the chance to look at LEF's protocol?

http://www.lef.org/protocols/prtcl-006.shtml
 
I would be greatly interested if you posted updates once in a while,
of course if you do not forget:)

I wish you well!

i

In article <[email protected]>, <[email protected]> wrote:
> Matt:
>
> I have been under the care of my neurologist for nearly three years now for
> Early Onset Alzheimer's Disease. I am 54 years old and I think that I have
> had every test known to man for my condition. For the last year, my doctors
> have had me on a regimen of the following:
>
> Reminyl 12 mg twice daily
> Vitamin E 1000 mg twice daily
> Vitamin C 1000 mg twice daily
> Ibuprofen (Advil) 500 mg nightly
>
> On my own I take (but they do not object), the following:
>
> Shark's Liver Oil gel capsules found at GNC
>
> I drink at least two (2) bottles of tonic water a day for leg cramps for the
> quinine in it. My doctors advises that quinine tablets were too much but
> tonic water was much better. Plus, I drink lots of water.
>
> I keep my brain very active by doing plenty of puzzles daily and trying to
> learn something new every day. I walk daily even when I really don't want
> to get out.
>
> During the last three months, I have seen a considerable improvement in my
> condition. Where I would not leave the house unaccompanied by one of my
> family members, I am now driving again. I am remembering things even my
> husband is forgetting.
>
> I am due for another MRI and tests this month and, hopefully, it will not
> show near the amount of brain atrophy that it did last year. Maybe this
> regimen does work but only time will tell. I am thankful for the time being
> that it is working for me, and that it has given me somemore time to enjoy
> my family.
>
> Kathy
>
>
> "Matt" <[email protected]> wrote in message
> news:[email protected]...
>> Hello,
>>
>> My aunt has compiled the following "rules of thumb" that my family
>> uses for our Alzheimer's prevention diet. Can anyone comment on these
>> points and/or possibly point to other places of reference so that we
>> can possibly learn more, maybe read about other perspectives/opinions
>> on Alzheimer's prevention with diet? Are there other steps we might
>> take above and beyond what is listed below?
>>
>> (My grandmother and great-grandmother have experienced Alzheimer's, so
>> my family is quite sensitive and aware of any reasonable prevention
>> measures that we can take.)
>>
>> -Matt
>>
>> [[ My aunt's compilation follows... ]]
>>
>> I've listed my prevention strategies in order of my perceived
>> importance. These are not proven to inhibit the disease, but they are
>> good health practices anyway..so what do you have to lose?
>>
>> 1. Choline - This amino acid improves neuro-transmission in the
>> memory portion of the brain. One of the reason that Grandma took the
>> drug Aricept was to increase the choline production in the brain.
>>
>> Choline can be found in eggs, green leafy vegetables, legumes, and
>> tofu. You can also by it in capsule form. There is no set daily
>> dosage requirement.
>>
>> 2. Vitamin E - A powerful anti-oxidant believed to be the most
>> important of all vitamins in preventing Alzheimer's. Most research
>> supports taking well above the daily recommended dosage. I take 1,000
>> mg. twice a day.
>>
>> 3. Vitamin C - Useful in the development of new brain cells which
>> slows down at the onset of Alzheimer's. Again research suggests a
>> higher than normal dosage. I take 1,000 mg. three times a day.
>>
>> 4. Fish oils - Omega 3 fatty acids are rich in fish oils. The
>> highest dosage is found in sardines, salmon, tuna and turbot. You
>> should be having a minimum of two servings per week. I take an fatty
>> acid supplement three times a day that contains both Omega 3 and 6.
>> Not only has it been found to improve brain efficiency, but it also
>> maintains good joint health and helps guard cholesterol levels.
>>
>> 5. Homocysteine level in Blood - The higher the level of
>> homocysteine, the more likely you are to develop the disease.
>> Homocysteines has a toxic effect on brain cells that can begin to age
>> the brain long before Alzheimer's sets in. A blood test can tell you
>> if your levels are elevated. Take 2 mg. of folic acid to keep them
>> under control. This is more than typically found in your daily
>> multivitamin.
>>
>> 6. Aluminum - Avoid ingesting it. Aluminum shows up in the
>> autopsies of Alzheimer's victims' brains. There toxic properties may
>> contribute to the destruction of brain cells. Minimize your use of
>> soda cans and aluminum cook ware. Watch for traces of harmful metals
>> in your antacid and other over-the-counter drugs.
>>
>> 7. Ibuprofen - This in the most controversial of the
>> recommendations I am making to you. This is because regular use of
>> Important may lead to liver and kidney damage, as well as irritate
>> your stomach lining. Nonetheless, inflammation is also believed to
>> play a big factor in Alzheimer's. The swelling of the brain membranes
>> is believed to play a part in the development of amyloid plaques in
>> the brain.
>>
>> I take one 200 mg. tablet twice a day for several months, then
>> alternate its use with an herbal supplement alternative. It is called
>> Zyflamend from New Chapter. The herb is not only unproven, but more
>> expensive than taking Advil. It is much fewer side effects, however.
>>
>> 8. Deep breathing - Oxygen to the brain is critically important
>> to normal reticular activity that keeps your brain alert. Aerobic
>> exercise, yoga or pilates are great ways to meet this need.
>>
>> 9. Water - Dehydration effects proper brain function, and most of
>> us walk around in this condition every day without even realizing it.
>> I keep a water bottle with me almost everywhere I go and drink one
>> full bottle first thing every morning.
>>
>> Hope this helps. For more information you may log onto the
>> Alzheimer's website at www.ALZ.org. The is some incredibly promising
>> research out there using passive immunization of Beta Amyloids that
>> are believed to be the primary cause of the disease. There are also a
>> new advances in slowing down the disease through stimulation of nerve
>> growth factors in the brain. Not much can be done at present until
>> symptoms arise in the victim. Many researchers believe that the
>> damage begins in the brain up to 20 years before these symptoms first
>> occur. For this reason, it is none to soon for each of you to take a
>> pro-active stance in your own personal prevention of the disease. I
>> already give [my children that are 11 and 14] extra E and C and a
>> choline supplement. They seldom drink soda or other canned drinks and
>> I try to push the water as much as I can. I just can't see a down
>> side to forming good habits now.

>
>
 
John de Hoog wrote

> I'm surprised not to see B12 (as methylcobalamin, 500-1500
> micrograms per day) and betaine. B12 works well with folic acid
> to reduce homocysteine, and betaine has been shown to reduce
> homocysteine dramatically.


Also thiamine (B1), niacin (B3) and inositol (B8), in
addition to folic acid (B9) and methylcobalamin (B12).
Taking the entire range of B-vitamins would probably be wisest.

Cheers,
Michael C Price
----------------------------------------
http://mcp.longevity-report.com
http://www.hedweb.com/manworld.htm
 
Matt <[email protected]> wrote or quoted:

> My aunt has compiled the following "rules of thumb" that my family
> uses for our Alzheimer's prevention diet. Can anyone comment on these
> points and/or possibly point to other places of reference so that we
> can possibly learn more, maybe read about other perspectives/opinions
> on Alzheimer's prevention with diet? Are there other steps we might
> take above and beyond what is listed below?


Consider going easy on the cake:

``Dietary restriction and 2-deoxyglucose administration improve behavioral
outcome and reduce degeneration of dopaminergic neurons in models of
Parkinson's disease''

- http://calorierestriction.org/pmid/?n=10398297

``Dietary restriction retards the age-associated loss of rat striatal
dopaminergic receptors''

- http://calorierestriction.org/pmid/?n=7291993

``Food restriction reduces brain damage and improves behavioral outcome
following excitotoxic and metabolic insults''

- http://calorierestriction.org/pmid/?n=9894871

``Dietary restriction protects hippocampal neurons against the
death-promoting action of a presenilin-1 mutation''

- http://calorierestriction.org/pmid/?n=10526115

``Dietary restriction increases the number of newly generated neural
cells, and induces BDNF expression, in the dentate gyrus of rats''

- http://calorierestriction.org/pmid/?n=11220789


....and maybe on the isoquinolines:

``Presence of tetrahydroisoquinoline and 1-methyl-tetrahydro-
isoquinoline in foods: compounds related to Parkinson's disease''

- http://calorierestriction.org/pmid/?n=3398705

``Endogenous risk factors in Parkinson's disease: dopamine and
tetrahydroisoquinolines''

- http://calorierestriction.org/pmid/?n=12866710

``Tetrahydroisoquinoline derivatives as possible Parkinson's
disease-inducing substances''

- http://calorierestriction.org/pmid/?n=1244014

``Role of noradrenergic system in the mechanism of action of
endogenous neurotoxin 1,2,3,4-tetrahydroisoquinoline:
biochemical and functional studies.''

- http://calorierestriction.org/pmid/?n=12020040

``Dopamine-derived endogenous N-methyl-(R)-salsolinol: its
role in Parkinson's disease''

- http://calorierestriction.org/pmid/?n=12200189

``In vitro pharmacological activity of the
tetrahydroisoquinoline salsolinol present in products from
Theobroma cacao L. like cocoa and chocolate''

- http://calorierestriction.org/pmid/?n=11025151
--
__________
|im |yler http://timtyler.org/ [email protected] Remove lock to reply.
 
Matt <[email protected]> wrote in message news:<[email protected]>...
> Hello,
>
> My aunt has compiled the following "rules of thumb" that my family
> uses for our Alzheimer's prevention diet. Can anyone comment on these
> points and/or possibly point to other places of reference so that we
> can possibly learn more, maybe read about other perspectives/opinions
> on Alzheimer's prevention with diet? Are there other steps we might
> take above and beyond what is listed below?
>
> (My grandmother and great-grandmother have experienced Alzheimer's, so
> my family is quite sensitive and aware of any reasonable prevention
> measures that we can take.)
>
> -Matt
>
> [[ My aunt's compilation follows... ]]
>
> I've listed my prevention strategies in order of my perceived
> importance. These are not proven to inhibit the disease, but they are
> good health practices anyway?.so what do you have to lose?
>
> 1. Choline - This amino acid improves neuro-transmission in the
> memory portion of the brain. One of the reason that Grandma took the
> drug Aricept was to increase the choline production in the brain.
>
> Choline can be found in eggs, green leafy vegetables, legumes, and
> tofu. You can also by it in capsule form. There is no set daily
> dosage requirement.
>
> 2. Vitamin E - A powerful anti-oxidant believed to be the most
> important of all vitamins in preventing Alzheimer's. Most research
> supports taking well above the daily recommended dosage. I take 1,000
> mg. twice a day.
>
> 3. Vitamin C - Useful in the development of new brain cells which
> slows down at the onset of Alzheimer's. Again research suggests a
> higher than normal dosage. I take 1,000 mg. three times a day.
>
> 4. Fish oils - Omega 3 fatty acids are rich in fish oils. The
> highest dosage is found in sardines, salmon, tuna and turbot. You
> should be having a minimum of two servings per week. I take an fatty
> acid supplement three times a day that contains both Omega 3 and 6.
> Not only has it been found to improve brain efficiency, but it also
> maintains good joint health and helps guard cholesterol levels.
>
> 5. Homocysteine level in Blood - The higher the level of
> homocysteine, the more likely you are to develop the disease.
> Homocysteines has a toxic effect on brain cells that can begin to age
> the brain long before Alzheimer's sets in. A blood test can tell you
> if your levels are elevated. Take 2 mg. of folic acid to keep them
> under control. This is more than typically found in your daily
> multivitamin.
>
> 6. Aluminum - Avoid ingesting it. Aluminum shows up in the
> autopsies of Alzheimer's victims' brains. There toxic properties may
> contribute to the destruction of brain cells. Minimize your use of
> soda cans and aluminum cook ware. Watch for traces of harmful metals
> in your antacid and other over-the-counter drugs.
>
> 7. Ibuprofen - This in the most controversial of the
> recommendations I am making to you. This is because regular use of
> Important may lead to liver and kidney damage, as well as irritate
> your stomach lining. Nonetheless, inflammation is also believed to
> play a big factor in Alzheimer's. The swelling of the brain membranes
> is believed to play a part in the development of amyloid plaques in
> the brain.
>
> I take one 200 mg. tablet twice a day for several months, then
> alternate its use with an herbal supplement alternative. It is called
> Zyflamend from New Chapter. The herb is not only unproven, but more
> expensive than taking Advil. It is much fewer side effects, however.
>
> 8. Deep breathing - Oxygen to the brain is critically important
> to normal reticular activity that keeps your brain alert. Aerobic
> exercise, yoga or pilates are great ways to meet this need.
>
> 9. Water - Dehydration effects proper brain function, and most of
> us walk around in this condition every day without even realizing it.
> I keep a water bottle with me almost everywhere I go and drink one
> full bottle first thing every morning.
>
> Hope this helps. For more information you may log onto the
> Alzheimer's website at www.ALZ.org. The is some incredibly promising
> research out there using passive immunization of Beta Amyloids that
> are believed to be the primary cause of the disease. There are also a
> new advances in slowing down the disease through stimulation of nerve
> growth factors in the brain. Not much can be done at present until
> symptoms arise in the victim. Many researchers believe that the
> damage begins in the brain up to 20 years before these symptoms first
> occur. For this reason, it is none to soon for each of you to take a
> pro-active stance in your own personal prevention of the disease. I
> already give [my children that are 11 and 14] extra E and C and a
> choline supplement. They seldom drink soda or other canned drinks and
> I try to push the water as much as I can. I just can't see a down
> side to forming good habits now.


Don't forgrt to cut refined and High-GI load carbs:

http://www.sciencedaily.com/releases/1999/07/990728073646.htm

A Mayo Clinic study has shown that 50 percent of a group of elderly
patients with mild cognitive impairment who also have a significantly
smaller hippocampus portion of the brain are likely to develop
Alzheimer's disease as compared to nine percent of patients with a
normal size hippocampus

http://www.defeatdiabetes.org/Archives of News/march2003.htm

Sustained High Blood Sugar Levels May Damage Brain's Key Memory Center
(03/10/03) An inability to quickly bring down high levels of sugar in
the blood is associated with poor memory and may help explain some of
the memory loss that occurs as we age, according to a new study. The
Study raises the possibility that exercise and weight loss, which help
control blood sugar levels, may be able to reverse some of the memory
loss that accompanies aging. The study is the first to show an
association between the size of the hippocampus, a key brain structure
for learning and memory, and the ability to control blood sugar levels
in the body, according to the researchers.

http://diabetes.about.com/cs/hyperglycemia/a/blnmemory03.htm

"For every person with Alzheimer's disease, there are some 8 people
with memory problems sufficient to affect the quality of their lives
who don't go on to develop dementia," says Dr. Convit. "Our work seeks
to understand what other medical factors influence memory in aging."
In fact, says Dr. Convit, there are now more than 20 reports in the
medical literature demonstrating that diabetics experience memory and
learning problems that cannot be explained away by the presence of
other conditions such as cardiovascular disease, which are often
associated with diabetes. Diabetics have very high levels of glucose
in the blood because the sugar cannot enter their tissues, where it is
broken down to do useful work.

TC
 
Once upon a time, our fellow Matt
rambled on about "Alzheimer's prevention diet: comment on this
family's strategies?."
Our champion De-Medicalizing in sci.med.nutrition retorts, thusly ...

>My aunt has compiled the following "rules of thumb" that my family
>uses for our Alzheimer's prevention diet.


Just about everything has been linked to causing Alzheimer's Disease.
There is no compiling proof that diet is the primary factor.

In my opinion, the best prevention is using your brain, not watching
television all day, and getting plenty of exercise.
--
John Gohde,
Achieving good Health is an Art, NOT a Science!

Health-with-Attitude is a weekly newsletter for people
trying to follow a Healthy Lifestyle.
http://groups.yahoo.com/group/Health-with-Attitude/
 
Matt <[email protected]> wrote:

<snip>

> 2. Vitamin E - A powerful anti-oxidant believed to be the most
> important of all vitamins in preventing Alzheimer's. Most research
> supports taking well above the daily recommended dosage. I take 1,000
> mg. twice a day.


Be careful with the E! High doses of this vitamin act as an effective
blood-thinner, and should not be taken without medical supervision if
one is already taking a prescribed blood thinner!

<snip>

> 6. Aluminum - Avoid ingesting it. Aluminum shows up in the
> autopsies of Alzheimer's victims' brains. There toxic properties may
> contribute to the destruction of brain cells. Minimize your use of
> soda cans and aluminum cook ware. Watch for traces of harmful metals
> in your antacid and other over-the-counter drugs.


I'm still waiting for a study on this one to indicate whether the
elevated levels of aluminum in the brains of Alzheimer's victims are the
cause of the disease or an effect of it. However, since the chances in
my estimation are fifty-fifty either way, I choose to avoid it....

<snip>

Blessed be,
Baird
 
In article <1g8ja1e.19ehhxczmczycN%[email protected]>,
Baird Stafford <[email protected]> wrote:
>Matt <[email protected]> wrote:


>> 6. Aluminum - Avoid ingesting it. Aluminum shows up in the
>> autopsies of Alzheimer's victims' brains. There toxic properties may
>> contribute to the destruction of brain cells. Minimize your use of
>> soda cans and aluminum cook ware. Watch for traces of harmful metals
>> in your antacid and other over-the-counter drugs.

>
>I'm still waiting for a study on this one to indicate whether the
>elevated levels of aluminum in the brains of Alzheimer's victims are the
>cause of the disease or an effect of it. However, since the chances in
>my estimation are fifty-fifty either way, I choose to avoid it....


Also, the insides of aluminum cans are coated -- the beverage doesn't
actually come into contact with aluminum.

-- David Wright :: alphabeta at prodigy.net
These are my opinions only, but they're almost always correct.
"If I have not seen as far as others, it is because giants
were standing on my shoulders." (Hal Abelson, MIT)
 
David Wright wrote
>>9. Water - Dehydration effects proper brain function, and most of
>>us walk around in this condition every day without even realizing it.

>
> No, we don't. If we did, we would be thirsty. OK, I'll make an
> exception for some older people, in whom the sense of thirst may
> have become weaker, but the notion that "most of us" are dehydrated
> is a medical urban legend.


No, it has a basis in fact

Eur J Appl Physiol Occup Physiol 1988;57(2):220-4

Improved thermoregulation caused by forced water intake in human desert
dwellers.

Kristal-Boneh E, Glusman JG, Chaemovitz C, Cassuto Y.

Ben-Gurion University of the Negev, Beer Sheva, Israel.

Residents of the Negev desert in Israel sustain a mild state of dehydration.
Low, concentrated urine outputs, high incidence of kidney diseases and high
hematocrit ratios characterize this population. Educational programs to
increase the awareness of the population to the dangers of dehydration have
undoubtedly failed. It was our purpose to see whether forced increased
drinking will affect the above variables. Ten healthy subjects were asked to
double their normal voluntary water intake without (phase II) and with salt
supplements (50 mM NaCl, 20 mM KCl) (phase III), for one week. After phases
II and III significant increases in body masses, decreased concentrations of
serum proteins, hemoglobin, hematocrit ratios and serum osmolalities were
found. No significant changes were found in the concentrations of sodium and
potassium in the serum. At the end of each phase, the subjects were asked to
exercise on a bicycle ergometer for 60 min at 50% VO2max in a heated chamber
at 45 degrees C, and 30%-50% relative humidity. Experiments were terminated
if and when heart-rates exceeded 180 bpm or the rectal temperature increased
to 39 degrees C. After both experimental phases, subjects increased their
tolerance to heat, extending the exercise periods by 25% and 30%. Compared
with their starting levels, hematocrit ratios, serum proteins and hemoglobin
concentrations increased in phases II and III while no changes were recorded
in the control period (phase I). It is suggested that spontaneous voluntary
water drinking in desert dwellers is not enough to achieve a true state of
"euhydration".

PMID: 3349990

Am Diet Assoc. 1999 Feb;99(2):200-6.

Erratum in:
J Am Diet Assoc 1999 Apr;99(4):411.

Water: an essential but overlooked nutrient.

Kleiner SM.

Nutritional Sciences Program, University of Washington, Seattle, USA.

Water is an essential nutrient required for life. To be well hydrated, the
average sedentary adult man must consume at least 2,900 mL (12 c) fluid per
day, and the average sedentary adult woman at least 2,200 mL (9 c) fluid per
day, in the form of noncaffeinated, nonalcoholic beverages, soups, and
foods. Solid foods contribute approximately 1,000 mL (4 c) water, with an
additional 250 mL (1 c) coming from the water of oxidation. The Nationwide
Food Consumption Surveys indicate that a portion of the population may be
chronically mildly dehydrated. Several factors may increase the likelihood
of chronic, mild dehydration, including a poor thirst mechanism,
dissatisfaction with the taste of water, common consumption of the natural
diuretics caffeine and alcohol, participation in exercise, and environmental
conditions. Dehydration of as little as 2% loss of body weight results in
impaired physiological and performance responses. New research indicates
that fluid consumption in general and water consumption in particular can
have an effect on the risk of urinary stone disease; cancers of the breast,
colon, and urinary tract; childhood and adolescent obesity; mitral valve
prolapse; salivary gland function; and overall health in the elderly.
Dietitians should be encouraged to promote and monitor fluid and water
intake among all of their clients and patients through education and to help
them design a fluid intake plan. The influence of chronic mild dehydration
on health and disease merits further research.

Publication Types:
Review
Review, Academic

PMID: 9972188
Cheers,
Michael C Price
----------------------------------------
http://mcp.longevity-report.com
http://www.hedweb.com/manworld.htm
 
In sci.life-extension David Wright <[email protected]> wrote or quoted:
> Matt <[email protected]> wrote:


> >9. Water - Dehydration effects proper brain function, and most of
> >us walk around in this condition every day without even realizing it.

>
> No, we don't. If we did, we would be thirsty. OK, I'll make an
> exception for some older people, in whom the sense of thirst may have
> become weaker, but the notion that "most of us" are dehydrated is a
> medical urban legend.


....perpetuated by studies like this one:

``The Nationwide Food Consumption Surveys indicate that a portion of the
population may be chronically mildly dehydrated. Several factors may
increase the likelihood of chronic, mild dehydration, including a poor
thirst mechanism, dissatisfaction with the taste of water, common
consumption of the natural diuretics caffeine and alcohol,
participation in exercise, and environmental conditions. Dehydration of
as little as 2% loss of body weight results in impaired physiological and
performance responses.''

- http://calorierestriction.org/pmid/?n=9972188
--
__________
|im |yler http://timtyler.org/ [email protected] Remove lock to reply.
 
Once upon a time, our fellow Tim Tyler
rambled on about "Re: Alzheimer's prevention diet: comment on this
family's strategies?."
Our champion De-Medicalizing in sci.med.nutrition retorts, thusly ...

>> >9. Water - Dehydration effects proper brain function, and most of
>> >us walk around in this condition every day without even realizing it.

>>
>> No, we don't. If we did, we would be thirsty. OK, I'll make an
>> exception for some older people, in whom the sense of thirst may have
>> become weaker, but the notion that "most of us" are dehydrated is a
>> medical urban legend.

>
>...perpetuated by studies like this one:
>
>``The Nationwide Food Consumption Surveys indicate that a portion of the
> population may be chronically mildly dehydrated. Several factors may


The water connection is an ancient concept developed by Dr. Abram
Hoffer with equally ancient research. :(

Actually, to be precise, forced water intake does not cure Alzheimer's
nor is it linked to it. It merely removes a segment of the population
misdiagnosed as suffering from dementia.

Ergo, the problem is you science geeks misdiagnosing people suffering
from dehydration as having dementia.

Just thought that you might want to know. :)
--
John Gohde,
Achieving good Health is an Art, NOT a Science!

Health-with-Attitude is a weekly newsletter for people
trying to follow a Healthy Lifestyle.
http://groups.yahoo.com/group/Health-with-Attitude/
 
John 'the Man' <[email protected]> wrote or quoted:
> Once upon a time, our fellow Tim Tyler rambled on about [...]:
> Our champion De-Medicalizing in sci.med.nutrition retorts, thusly ...


> >> >9. Water - Dehydration effects proper brain function, and most of
> >> >us walk around in this condition every day without even realizing it.
> >>
> >> No, we don't. If we did, we would be thirsty. OK, I'll make an
> >> exception for some older people, in whom the sense of thirst may have
> >> become weaker, but the notion that "most of us" are dehydrated is a
> >> medical urban legend.

> >
> >...perpetuated by studies like this one:
> >
> >``The Nationwide Food Consumption Surveys indicate that a portion of the
> > population may be chronically mildly dehydrated. Several factors may

>
> The water connection is an ancient concept developed by Dr. Abram
> Hoffer with equally ancient research. :(
>
> Actually, to be precise, forced water intake does not cure Alzheimer's
> nor is it linked to it. It merely removes a segment of the population
> misdiagnosed as suffering from dementia.
>
> Ergo, the problem is you science geeks misdiagnosing people suffering
> from dehydration as having dementia.


FWIW, I never meant to make any claims about proper hydration curing
any degenerative disorders.

I do think that relatively few individuals are properly hydrated much of
the time, though.

Personally, I find it essential to carry a water bottle around with me
to stop me from entering what are plainly states of mild dehydration.

I see a few others following this practice - but only a few.
--
__________
|im |yler http://timtyler.org/ [email protected] Remove lock to reply.
 
Once upon a time, our fellow Tim Tyler
rambled on about "Re: Alzheimer's prevention diet: comment on this
family's strategies?."
Our champion De-Medicalizing in sci.med.nutrition retorts, thusly ...

>I do think that relatively few individuals are properly hydrated much of
>the time, though.
>
>Personally, I find it essential to carry a water bottle around with me
>to stop me from entering what are plainly states of mild dehydration.
>
>I see a few others following this practice - but only a few.


At least one study was published last year that said that was just a
bunch of hooey. :)

The elderly are chronically dehydrated in the extreme. That does not
mean that the average normal person needs to be sipping at the water
trough all day long.
--
John Gohde,
Feeling Great and Better than Ever!

Healers who believe in the healing power of nature,
Vis Mediatix Naturae, worship Hygeia and the vital force.
http://tutorials.naturalhealthperspective.com/history.html
 
On Mon, 2 Feb 2004 02:19:52 GMT, "John de Hoog" <[email protected]>
wrote:

>I'm surprised not to see B12 (as methylcobalamin, 500-1500 micrograms per
>day) and betaine. B12 works well with folic acid to reduce homocysteine, and
>betaine has been shown to reduce homocysteine dramatically.


One problem with betaine is that it is quite osmotic active and
activated aldose reductase which produce sorbitol from glucose in
cells, which is also osmotic active and are very little mobile over
membranes since it is sterically hindered to pass the Cl-regulated
channel that do release taurine and beta-alanine when cell is volume
or osmotically challenged (hypoosmosis), the increased sorbitol
steady-state concentration if rate of turnover is not increased in
parallell with synthesis will increase osmotic pressure inside and
thus force taurine and betaine to leave cell thus making lack of
protection against hyperhomocysteinamia and lack of protection against
uncontrolled glycation, eg. by lysine of fructose to form an Amadori
product 1-amino-1-deoxyfructose lysine adduct) which most possibly
taurine may prevent to be formed by substituting lysine in the normal
reaction since normally, taurine will be in great excess as free amino
acid in cells (maybe one of the reasons intake of free amino acids may
be hazardous, while intake of taurine is not dangerous at all since
that will increase protection against formation of such derangeous
products as AGEs.

(There are several articles about taurine as glycation scavenger), but
here you should read Nature, vol 414, p. 413ff, Michael Brownlee,
Biochemistry and molecular cell biology of diabetic complications
which doesn't mention one word about taurine, but taurine is kicked
out of cell by mechanism 1 (several articles on cell volume regulation
taurine as search word, while it protects against glycation products,
it is involved in some phosporylations, and seem to protect against
PKC activation.
 
Alf Christophersen wrote...

> One problem with betaine is that it is quite osmotic active and
> activated aldose reductase which produce sorbitol from glucose in
> cells, which is also osmotic active and are very little mobile over
> membranes since it is sterically hindered to pass the Cl-regulated
> channel that do release taurine and beta-alanine when cell is volume
> or osmotically challenged (hypoosmosis), the increased sorbitol
> steady-state concentration if rate of turnover is not increased in
> parallell with synthesis will increase osmotic pressure inside and
> thus force taurine and betaine to leave cell thus making lack of
> protection against hyperhomocysteinamia and lack of protection against
> uncontrolled glycation, eg. by lysine of fructose to form an Amadori
> product 1-amino-1-deoxyfructose lysine adduct) which most possibly
> taurine may prevent to be formed by substituting lysine in the normal
> reaction since normally, taurine will be in great excess as free amino
> acid in cells (maybe one of the reasons intake of free amino acids may
> be hazardous, while intake of taurine is not dangerous at all since
> that will increase protection against formation of such derangeous
> products as AGEs.


Alf,

That was a bit difficult to follow, but what happens to people (like us) who
supplement 2 grams of taurine a day in addition to a moderate amount of
betaine?

--
John de Hoog
http://dehoog.org