To continue my thesis that the story of the metabolic syndrom and the level of diabetes is not a simple straight line cause and effect of total carbs , we next look at fat source and these risk levels. In short, this research shows that consumption of animal fat is related to risk for the risk factors: http://care.diabetesjournals.org/cgi/content/full/26/2/302 Again the story is much more complex then high carb/low carb diets in what is a very involved multi level metabolic process for the risk of the syndrom and diabetes. Fat, type and amount, type and amount of carbs, exercise, weight, genetics and time at risk are all involved and each plays an interdependent part. In general I think it safe to say that high sat fat with high gi/gl carbs in excess of energy needs, sedentary lifestyle, over a considerable time is the combination which produces the highest risk profile.
<[email protected]> wrote in message news:[email protected]... > To continue my thesis that the story of the metabolic syndrom and the level of diabetes is not a > simple straight line cause and effect of total carbs , we next look at fat source and these risk > levels. In short, this research shows that consumption of animal fat is related to risk for the > risk factors: > > http://care.diabetesjournals.org/cgi/content/full/26/2/302 > > Again the story is much more complex then high carb/low carb diets in what is a very involved > multi level metabolic process for the risk of the syndrom and diabetes. Fat, type and amount, type > and amount of carbs, exercise, weight, genetics and time at risk are all involved and each plays > an interdependent part. In general I think it safe to say that high sat fat with high gi/gl carbs > in excess of energy needs, sedentary lifestyle, over a considerable time is the combination which > produces the highest risk profile. I believe this is a balanced and sensible story. GWC
[email protected] wrote in message news:<[email protected]>... > To continue my thesis that the story of the metabolic syndrom and the level of diabetes is not a > simple straight line cause and effect of total carbs , we next look at fat source and these risk > levels. In short, this research shows that consumption of animal fat is related to risk for the > risk factors: > > http://care.diabetesjournals.org/cgi/content/full/26/2/302 > > Again the story is much more complex then high carb/low carb diets in what is a very involved > multi level metabolic process for the risk of the syndrom and diabetes. Fat, type and amount, type > and amount of carbs, exercise, weight, genetics and time at risk are all involved and each plays > an interdependent part. In general I think it safe to say that high sat fat with high gi/gl carbs > in excess of energy needs, sedentary lifestyle, over a considerable time is the combination which > produces the highest risk profile. Ya think? Did you consider the source of this study? It may be relevant as to whether or not this study has any credibility an the scientific sense. Dietary Fat Intake as Risk Factor for the Development of Diabetes http://care.diabetesjournals.org/cgi/content/full/26/2/302#T2 The study is part of the Multicenter Nutritional Study of the Mediterranean Group for the Study of Diabetes (MGSD), and it was financially supported by the MGSD, Novo Nordisk A/S, and Farmaserve Hellas. Mediterranean Group for the Study of Diabetes Supported by an unrestricted educational grant from Servier: http://www.servier.com/groupe/recherche.asp From the above web page: ------------- Servier Research & Development The motor driving innovation and progress SERVIER is maintaining its steep growth profile by bringing seven innovative drugs onto the market in the next few years, addressing the following treatment sectors: menopause, osteoporosis, diabetes, cardiology, hypertension, angina, heart failure, in neuropsychiatry and in oncology. ------------ Click on the Metabolic disease link: quote --------------- Metabolic disease Several antidiabetic agents are under development: they include S 21403, a compound with a novel effect on pancreatic insulin secretion in that it causes a rapid decrease in blood glucose levels over a very short duration (it has glucose-lowering activity only after meals, not in between). It has two potential benefits: it could prevent postprandial surges in hyperglycemia, it could avoid the decrease in blood glucose that tends to persist after meals with conventional glucose-lowering medication. S 21403 could play an important role in the treatment of diabetes alongside the many other pharmaceutical products already available. Another highly promising compound, S 15261, is currently in Phase II development. Its potential benefits are two-fold in that it acts on both insulin secretion and insulin target tissues. ------------end quote Back to the Mediterranean Group for the Study of Diabetes USEFUL CONTACTS page: http://www.mgsd.net/uk/page2418.asp Alfediam American Diabetes Association EASD IDF National Library of Medicine Servier Société Marocaine d'Endocrinologie About these contacts: ****************** About Alfediam message for the president of Alfrediam: http://www.alfediam.org/alfediam/president.asp quote----------- Elle est un partenaire privilégié des firmes pharmaceutiques qui travaillent en recherche et développement sur ce domaine d'importance majeure qu'est le Diabète. --------------end quote rough translation to english: It (Alfrediam) is a privileged partner of the pharmaceutical firms which work under development research and on this field of major importance which is the Diabetes. *************** American Diabetes Association corporate sponsors: http://www.diabetes.org/aboutus/corporatesponsors/makingadifference.jsp ***************** EASD - European Association for the Study of Diabetes (EASD) click on the corporate membership link on this page: http://www.easd.org/ *************** IDF - International Diabetes Federation corporate sponsors: http://www.idf.org/home/index.cfm?node=338 ************** Servier, see above ************* All very interesting info to know. What would happen to the sales of these companies if it were found that simply restricting refined carbs in the diet can resolve most cases of obesity and diabetes? Here is one very good piece of research that isn't connected to the pharmaceutical companies that indicate clearly that blood glucose kills b-cells and that most fats protect them: http://www.eje.org/eje/149/0099/1490099.pdf This is what real science looks like. TC
I'm not dismissive alone of research because it has industry funding, nor do I see any information to support a concerted effort to promote less then healthy food consumoption just to increase markets for medical services/meds. You presented some study said to be free of commercial influence. It was funded by the ADA and the NIH. It would take but one or a few steps there to find commercial sponsership and research funding from commercial intrests, including a revolving door with the biomed/drug biz in people involved. Also, both promote a highish carb diet. This is the telling point, the research should be accepted on it's merits not it's funding source. If in specific cases undue 3rd party influence can be shown, then it should be known, but a sweeping dismissal doesn't serve. Bty, I had read the article you reference before, thanks.
I read the article. A family history of diabetes and a sedentary lifestyle seem to be much better indicators. They are talking about 3 grams of fat +/- 2 grams per day difference between the diabetic and the control, and the IFG control group has a larger intake of daily animal fat than the RDM group. Sorry, look like careful presentation of the correlations to prove a desired hypothesis. Notes: RDM = recently diagnosed diabetic UDM = unknown diabetes (very high fasting glucose level) IFG = impaired fasting glucose (higher than normal glucose after fast) Control group for a studied group was comprised of non-diabetic origin.
[email protected] (tcomeau) wrote in message news:<[email protected]>... > > Several antidiabetic agents are under development: they include S > 21403, a compound with a novel effect on pancreatic insulin secretion Increasing insulin is far more damaging than reducing dietary carb intake as the means of reducing serum glucose. --Hua Kul
