Apple juice / cognitive performance

Discussion in 'Health and medical' started by Doe, Feb 27, 2004.

  1. Doe

    Doe Guest

    J Nutr Health Aging. 2004;8(2):92-7. Related Articles, Links

    Apple juice prevents oxidative stress and impaired cognitive performance caused by genetic and
    dietary deficiencies in mice.

    Rogers EJ, Milhalik S, Orthiz D, Shea TB.

    Center for Cellular Neurobiology and Neurodegeneration Research, Department of Biological Sciences,
    University of Massachusetts Lowell, One University Avenue, Lowell, MA 01854, Tel: 978-934-2881, Fax:
    978-934-3044, Email: [email protected]

    Increased oxidative stress contributes to the decline in cognitive performance during normal aging
    and in neurodegenerative conditions such as Alzheimer s disease. Dietary supplementation with fruits
    and vegetables that are high in antioxidant potential have in some cases compensated for dietary
    and/or genetic deficiencies that promote increased oxidative stress. Herein, we demonstrate that
    apple juice concentrate, administered ad libitum in drinking water, can compensate for the increased
    reactive oxygen species and decline in cognitive performance in maze trials observed when normal and
    transgenic mice lacking apolipoprotein E are deprived of folate and vitamin E. In addition, we
    demonstrate that this protective effect is not derived from the sugar content of the concentrate.

    PMID: 14978604 [PubMed - in process]

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