While I don't have a laptop computer, the backpack that I sometimes use has a seperate padded slot exclusively for laptop computers. It's a nice backpack, and I notice they are on sale.
I have a neoprene sleeve for my laptop and put that combo in my backpack. It survived many 15 mile commutes to and from work that way. When I'm not biking I often commute by motorcycle and it survived in a pannier many more times in the same configuration. There are some hardshell backpacks that you can get, I've seen them mostly on motorcycle riders but a few times on bicyclists also, found this link http://www.ebags.com/boblbee/megalo...ckpack/product_detail/index.cfm?modelid=17905 The bags at that site are fairly expensive. I have seen similar bags at CompUSA for much less, but did not look closely to see what the quality was like.