cancer prevention / vegetarian diet



Neoplasma. 2004;51(1):30-3. Links

Oxidative DNA damage in relation to nutrition.

Krajcovicova-Kudlackova M, Dusinska M.

Institute of Preventive and Clinical Medicine;, Bratislava,
833 01 Slovak Republic. [email protected]

Oxidative DNA damage in humans could arise also from
incorrect nutritional habit and life style. DNA strand
breaks with apurinic/apyrimidinic sites, oxidized purines
and oxidized pyrimidines were assessed in 24 subjectively
healthy vegetarians (plant food, dairy products, eggs) and
compared with 24 non-vegetarians (traditional diet, general
population). DNA strand breaks + oxidized purines are
significantly reduced in vegetarians (p<0.05), DNA strand
breaks are nonsignificantly decreased. The sufficient
antioxidative status (overthreshold values of natural
essential antioxidants, which mean a reduced risk of free
radical disease) is crucial in free radical defense. Intake
of protective food commodities (fruit, vegetables, dark
grain products, grain sprouts, oil seeds) is significantly
higher in vegetarians. Alternative nutrition subjects have a
significantly increased plasma levels of vitamin C, vitamin
E, beta-carotene with high incidence of overthreshold values
(92% vs. 42% - vitamin C, 67% vs. 33% - vitamin E, 67% vs.
17% - beta-carotene). There is recorded a significant
inverse linear correlation between values of DNA strand
breaks + oxidized purines and vitamin C or beta-carotene
levels (p<0.01, p<0.05). Vegetarian diet is significantly
more rich source of antioxidants. The results of reduced
endogenous DNA damage and higher antioxidative status in
vegetarians document that a correct vegetarian nutrition
might represent an effective cancer prevention.

PMID: 15004656 [PubMed - in process]


Who loves ya. Tom Jesus Was A Vegetarian! Man Is A Herbivore! DEAD