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Hi
I have a dumb question
Can someone explain me what does 1/2Ne stand for in the expression of
F = 1/2Ne / (1/2Ne + 2u)
They only thing that I though was that 1/2Ne represents 1 allele in the population, and (1/2Ne + 2u)
represents that allele on the next generation with 2u mutations added. since we are estimating whats
the probability of this allele being IBD to the allele of the previous generation if u = 0 then F =
1, and theres a 100% probability that the allele represented by the denominator is IBD to the allele
that the numerator represents.
thnks
hans
I have a dumb question
Can someone explain me what does 1/2Ne stand for in the expression of
F = 1/2Ne / (1/2Ne + 2u)
They only thing that I though was that 1/2Ne represents 1 allele in the population, and (1/2Ne + 2u)
represents that allele on the next generation with 2u mutations added. since we are estimating whats
the probability of this allele being IBD to the allele of the previous generation if u = 0 then F =
1, and theres a 100% probability that the allele represented by the denominator is IBD to the allele
that the numerator represents.
thnks
hans