grahamspringett said:
I've been off the bike for a month with a cold and sinus infection which then got onto my chest. I'm recovered now and am about to start some easy recovery rides.
What has happened to my mitochondria during my inactivity? What are the physiological changes which occur during detraining?
I am no physiologist. But just taking this little challenge as a game, I'd say that not much happened to your mitochondria with such a short period off bike. Euhh well. It may be border line a bit. No change in number, maybe decrease in size?
On the other hand, you probably lost most of the extra plasma volume gained through sustained training. As a result, you may experiment higher than usual heart rates. More importantly most enzymes (by the dozens, don't ask me their names, I call them all 'anythingkinaze') involved in aerobic metabolism probably don't remember how to work fast. They are now stupid and slow, which is likely slowing down its rate (aerobic metabolism) by quite a lot. The two causes listed in this paragraph are probably what hits you the most. Mitochondria alone can't do much. They need the employees. You cut down on orders made to the plants for a month, employazes that got lazy and slow will need some time to gain back their efficiency. But the plants themselves (mitochondria) won't disappear with such a small period off bike in my humble and uneducated opinion. (And besides, they may have been little busy fighting against this nasty bug you got

)
Muscles, depending on several factors, maybe intact maybe little atrophy, maybe will feel incredibly fresh. Hormones? Likely going to overreact. Body weight? Maybe little loss maybe fortunate after all? And of course, fatigue will kick in earlier probably because of... Bah, I may as well stop there and leave all the room to the real experts
(Don't hesitate to denote any mis-information I may have given to the OP. I was just gaming here.)
Enjoy your rebuild and take care!
PS - Over time, I came to realize that often, these season "bad lucks" don't turn out to have such a negative impact on athletes' season. Maybe it's my plans that are faulty after all

PPS - Over time I carried on this fantasy of asking my top level contenders to self-inoculate themselves with several roots influanza and cold viruses. I'd rather be sure they get sick if at least I can control when it's going to happen.
