Enhancement of absorption / lecithin

Discussion in 'Health and medical' started by Doe, Jan 24, 2004.

  1. Doe

    Doe Guest

    Biosci Biotechnol Biochem. 2003 Dec; 67(12): 2548-55. Related Articles, Links

    Enhancing Effect of Lipids and Emulsifiers on the Accumulation of Quercetin Metabolites in Blood
    Plasma after the Short-term Ingestion of Onion by Rats.

    Azuma K, Ippoushi K, Ito H, Horie H, Terao J.

    National Institute of Vegetable and Tea Science, National Agricultural Research Organization.

    The effects of co-ingested lipids and emulsifiers on the accumulation of quercetin metabolites in
    blood plasma after the short-term ingestion of onion by rats were investigated. Plasma extracts of
    rats that had been fed onion-containing diets for one and two weeks were analyzed by HPLC with
    electrochemical detection after a treatment with sulfatase/beta-glucuronidase. Almost all of the
    quercetin metabolites in the plasma were sulfate/glucuronide conjugates of quercetin and
    isorhamnetin. More than 4.6% (w/w) of soybean oil in the diets significantly enhanced the
    accumulation of quercetin metabolites in the plasma. Fish oil and beef tallow increased this to an
    extent similar to that with soybean oil, and lecithin was more effective than the other three
    lipids. Two emulsifiers, sodium caseinate and sucrose fatty acid ester, also showed an enhancing
    effect on the accumulation of quercetin metabolites. These results indicate that co-ingested lipids
    and emulsifiers could enhance the bioavailability of quercetin glucosides in onion.

    PMID: 14730132 [PubMed - in process]

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