Glucosamine is a precursor for Chondroitin uptake, and should be taken six hours beforehand. The best, purest Choindroitin is at springtimeinc.com, the "J-Flex" made for horses, or buy the human capsules. If your knees are bad, lay on your back with your legs over a box or chair or crate with a pillow on it. You can do this in bed if needed. Get those hips square or they will beat up your knees! God bless!