INCREASED IRON / asthma

Discussion in 'Food and nutrition' started by Doe, Jan 27, 2004.

  1. Doe

    Doe Guest

    >>snip<<
    These observations suggest that increased Fe and decreased Se concentrations in patients with
    childhood asthma may be responsible for the oxidant/antioxidant imbalance.
    >>snip<<

    Biol Trace Elem Res. 2004 Jan; 97(1): 31-42. Related Articles, Links

    Alterations in Plasma Essential Trace Elements Selenium, Manganese, Zinc, Copper, and Iron
    Concentrations and the Possible Role of these Elements on Oxidative Status in Patients with
    Childhood Asthma.

    Kocyigit A, Armutcu F, Gurel A, Ermis B.

    Department of Biochemistry, Medical Faculty, Harran University, Sanliurfa, Turkey.

    The aim of the present study is to evaluate the status of plasma essential trace element selenium
    (Se), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe) concentrations and the effect of these
    elements on oxidative status in patients with childhood asthma. Plasma Se, Mn, Cu, and Zn
    concentrations were determined by atomic absorption spectrophotometry (AAS) and Fe concentrations,
    malondialdehyde (MDA), and total antioxidant capacity (TAC) were determined by the colorimetric
    method. The plasma MDA/TAC ratio was calculated as an index of oxidative status. Plasma albumin
    levels were measured to determine nutritional status. Plasma Fe concentrations, MDA levels and the
    MDA/TAC ratio were significantly higher (p<0.001, p<0.001, and p<0.01, respectively) and Se and Mn
    concentrations and TAC were lower (p<0.01, p<0.05, and p<0.01, respectively) in patients when
    compared to the healthy subjects. Plasma Zn, Cu, and albumin levels were not found to be
    significantly different in patients and controls
    (p>.05). There were positive relationships between plasma MDA and Fe (r=0.545, p<0.001) and TAC and
    Se (r= 0.485, p<0.021), and a negative correlation between TAC and MDA values (r= -0.337,
    p<0.031) in patients with childhood asthma. However, there was no correlation between these trace
    elements and albumin content in patient groups. These observations suggest that increased Fe and
    decreased Se concentrations in patients with childhood asthma may be responsible for the
    oxidant/antioxidant imbalance.

    PMID: 14742898 [PubMed - as supplied by publisher]

    --------------------------------------------------------------------------
    ------

    Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore!
    http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING
    http://pages.ivillage.com/ironjustice/deadpeoplewalking
     
    Tags:


Loading...