Sleepyman <
[email protected]> wrote in
news:[email protected]:
> Wondering about Insulin Resistance. As I know there is no specific insulin resistance test, do we
> know if it is a semi-constant level, that can be brought down slowly, or is it more similar to Bg
> levels, in that it can change rapidly?
There are actually a couple of methods for measuring insulin resistance, but they are usually
reserved for research settings.
As there are a number of mechanisms that cause insulin resistance, some understood fairly well
and some not at all well, and there are a number of time scales involved. Some are reversible
and some not.
Three of the most common mechanisms for increasing insulin resistance are aging, weight gain, and
sedentary life style. While these aspects are clearly related, it appears that they function to some
degree independently.
It is, of course, fairly difficult to do much about aging. Removing excess weight, or more properly
body fat ratio, seems to have a range of difficulty in the population. None-the-less it is clear
that reducing excess weight will reduce insulin resistance. Sometimes a relatively small weight loss
will produce noticeable results. The time scale is, naturally, the time scale of the weight loss.
Exercise effects insulin resistance on several time scales. There is an immediate effect during
exercise as insulin independent glucose disposal pathways are opened up. As exercise becomes
regular, other insulin resistance reductions appear and persist for various periods from a few days
to a few weeks. It may take a few days to a few weeks to begin to see these results.