J
James Michael H
Guest
I sent the following response to J Am Geriatr Soc. 2004 Jan;52(1):106-11. I thought some here may be
interested.
It is my hypothesis (1985) that depression may result from low dehydroepiandrosterone (DHEA). This
has since been supported. In 1994, I first suggested low DHEA may trigger oncogene activity and
explained this in the context of breast cancer. Therefore, the findings of Goodwin, et al., (J Am
Geriatr Soc. 2004 Jan;52(1):106-11) were not unexpected.
I suggest low DHEA participated in both depression and the initiation of breast cancer in the
subjects of the study. Depression manifests itself before the cancer. Low DHEA may explain the
"decreased survival after a diagnosis of breast cancer." My principal hypothesis is that DHEA
optimizes transcription and replication of DNA. Therefore, DHEA levels affect all tissues. Reduced
DHEA, therefore, may also account for "studies of [connections between] depression and other acute
illnesses such as hip fracture and myocardial infarction."
James Michael Howard www.anthropogeny.com
interested.
It is my hypothesis (1985) that depression may result from low dehydroepiandrosterone (DHEA). This
has since been supported. In 1994, I first suggested low DHEA may trigger oncogene activity and
explained this in the context of breast cancer. Therefore, the findings of Goodwin, et al., (J Am
Geriatr Soc. 2004 Jan;52(1):106-11) were not unexpected.
I suggest low DHEA participated in both depression and the initiation of breast cancer in the
subjects of the study. Depression manifests itself before the cancer. Low DHEA may explain the
"decreased survival after a diagnosis of breast cancer." My principal hypothesis is that DHEA
optimizes transcription and replication of DNA. Therefore, DHEA levels affect all tissues. Reduced
DHEA, therefore, may also account for "studies of [connections between] depression and other acute
illnesses such as hip fracture and myocardial infarction."
James Michael Howard www.anthropogeny.com