Lipitor Have Withdrawal Dangers?



L

Leerand

Guest
I've been taking 10mg of Lipitor daily for 2 months. Any dangers in suddenly discontinuing Lipitor?

Lee
 
"LeeRand" <[email protected]> wrote in message
news:[email protected]...
> I've been taking 10mg of Lipitor daily for 2 months. Any dangers in suddenly discontinuing
> Lipitor?
>
> Lee

I think not in the sense you mean. Obviously, your cholesterol may go up over time.

Bill - not a Dr.
 
YES, there is evidence that it is dangerous, particularly in the first few weeks, when discontinuing
Lipitor - Please be sure you are under close scrutiny by your physician. Patients going off Lipitor
are more likely to have a cardiac event or a stroke than they were before starting the drug.

One study indicates that there are more coronary events when people stop taking statins (Definitely
talk with your doctor on this): http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMe-
d&list_uids=11914253&dopt=Abstract Withdrawal of statins increases event rates in patients with
acute coronary syndromes. The dangers of getting off statins. See also:
http://www.lipidsonline.org/commentaries/al_abstract.cfm?abs_id=Abs030

Another study showed that "Our data suggest a platelet hyperactivation state in the second week
after statin discontinuation which is partially related to raised LDL-C. Such a finding could
participate in the increased cardiovascular event rate after statin discontinuation."

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12958617&dop-
t=Abstract

Platelet hyperactivity after statin treatment discontinuation. Puccetti L, Pasqui AL, Pastorelli M,
Bova G, Di Renzo M, Leo A, Cercignani M, Palazzuoli A, Auteri A, Bruni F. Department of Clinical
Medicine and Immunological Sciences, Internal Medicine Division, Policlinico Le Scotte, V. le
Bracci, 53100, Siena, Italy. [email protected]

For patients who cannot tolerate the statin adverse effects of myopathy, peripheral neuropathy and
memory loss/amnesia, besides becoming disabled they risk death in stopping the very drug causing the
disability. What a bitter irony.

Please be cautious.

"LeeRand" <[email protected]> wrote in message
news:[email protected]...
> I've been taking 10mg of Lipitor daily for 2 months. Any dangers in suddenly discontinuing
> Lipitor?
>
> Lee