Quoted message said:Subject: Looking for the evidence on mercury
Quoted message said:From: "Peter Moran" [email hidden]
LOL, Peter, have you forgotten your track record here of NOT
seeing evidence right smack dab in front of your nose???
As in NO cover-ups??????''
Quoted message said:Me > >Furthermore it is only those with very large numbers
of amalgam fillings,
Quoted message said:Quoted message said:and I mean something like forty or fifty, who are at all
likely to be approaching the lowest levels at which even
the most tenous evidence for mercury poisoning exist.
Quoted message said:Jan> This is an absolute lie. I posted the abstacts of low
Jan> levels, but Peter
is
Quoted message said:STILL repeated the EOM speech he has been taught.
Still with the insults.
Still with the lies.
Quoted message said:
I have looked at all the evidence you have presented, and
have allowed that some researchers, not others,
Which others??
Quoted message said:have, via sophisticated neuropsychiatric testing, found .
mild subclinical (non-symptomatic) effects below the levels
that are generally regarded as ever causing the mildest
mercury poisoning in occupational settings
Where did you read about *mild* mercury poisoning, is that
anything like being partly pregnant??
Quoted message said:No one has produced anything other than very dubious
anecdotal evidence for gross illness being caused by mecury
poisoning from amalgams.
Show me the abstracts that show this to be a lie.
Peter Moran
Where did you read the *gross* illness???
Did you make it up?????
Why are you posting this again, when you couldn''t answer
the last post?????
When are you going to STOP lying??
The sites below prove you claim of 40-50 amalgams is a lie.
ephca.comci&cme.htmOpen ↗
The biology of mercury toxicity has usually been studied
after acute short exposure (hours, days) not chronic (years)
low long term exposure. Exposure from ****amalgam
fillings**** occurs without interruption for many years and
if 3-17 micrograms are lost per day in vapor alone that is
1095 micrograms to 6200 micrograms per year which can amount
to as much as 120 mg over 20 years from the fillings alone---
that's a huge amount!!!
The point being, it is the infant in utero that suffered
most on exposure to low level, toxins, not the mother.
Combined mercury toxicities can be devastating, as I
reference below and in the many references available on the
testfoundation.comtestfoundation.comOpen ↗ website
<snip>
However, the fact is that it is quite easy to detect mercury
emitting from one ****amalgam****
using these analyzers. Therefore, the "estimate" by this ADA
spokesman is way too low.
Now on to low levels.
9. The half-time for the elimination of a single dose of
mercury is extremely long, certainly at least 30 days
for the whole body, and perhaps as long as 10,000 days
for the brain. Multiple small doses will therefore
result in body accumulation.
10. The earliest symptoms of long term, low level mercury
poisoning are subclinical and neurological.
Consequently, due to their subtlety, these symptoms are
easily misdiagnosed.
S. Soderstrom, A Fredriksson, L. Dencker, T. Ebendal, "The
effect of mercury vapour on cholinergic neurons in the
fetal brain: studies on the expression of nerve growth
factor and its low- and high-affinity receptors,"
Developmental Brain Research 85, 96-108 (1995)
These findings suggest that low levels of prenatal mercury
vapour exposure can alter the levels of the NGF and its
receptors, indicating neuronal damage and disturbed trophic
regulations during development.
What are the Health Impacts?
Mercury is an element that occurs naturally in the
earth?s crust. Most people and wildlife can generally
tolerate the extremely low levels of this naturally
occuring substance. When mercury enters the body it
becomes concentrated in tissue, an effect known as
bioaccumulation. Since this element is toxic at very low
concentrations, even slight increases in the minute
concentrations naturally present in the environment can
have serious effects on humans and wildlife.
Mercury is a neurotoxin in low doses, affecting the
functioning and development of the nervous system. Depending
on the level of exposure, this toxin can have varied health
effects ranging from mental retardation to death.
Mercury definitely has the ability to cross the placental
membranes and so
Quoted message said:Quoted message said:cause health disorders in the unborn child. In studies
done by Marsh et al
in
Quoted message said:Quoted message said:1981 and 1987, they showed that mothers with hair mercury
levels of 70-640 m
g/gm of hair during pregnancy have 30% increased risk of
psychomotor and
other
Quoted message said:Quoted message said:neurological disorders in their infants. Even as low as
10-20 m g/gm can increase risk to 5% (WHO 1990).
Haley and other scientists, including Vimy and
Lorscheider, found in experiments on rat brains that
chronic inhalation of low-level mercury ? at levels
that simulate exposure to amalagam fillings ? can
inhibit brain chemistry, producing lesions similar to
those in Alzheimer¹s diseased brains. Mercury
inhibits the efficiency of tubulin, a protein vital
to brain cells, they explain.
To Tell the Tooth
by Steven F. Hinchey, D.M.D.
While that is true, the cumulative release of low doses of
mercury may be the same or more than recognized forms of
mercury poisoning. Is it worse to have a mega exposure to
mercury vapor at one time, or is it worse to have a
continued low dose exposure over time? The theories of
dental caries (tooth decay) now point to frequency of
exposure to sugar as a strategy to reducing tooth decay. In
other words, frequent small doses of sugar are more harmful
to the teeth than one mega dose of sugar. The same theory
probably holds true for mercury. Allergy desensitization
techniques use the theory of very low dose exposures over a
long period of time to cure.
tinyurl.comcdb0Open ↗
: Sci Total Environ. 2003 Jan 1;301(1-3):43-50. Related
: Articles, Links
Influence of amalgam fillings on Hg levels and total
antioxidant activity in plasma of healthy donors.
Pizzichini M, Fonzi M, Giannerini F, Mencarelli M, Gasparoni
A, Rocchi G, Kaitsas V, Fonzi L.
Department of Biomedical Sciences, University of Siena, Via
A Moro 8, 53100 Siena, Italy. [email hidden]
In order to evaluate the influence of specific factors on
mercury (P-Hg) levels and antioxidant power (P-FRAP) in
human plasma, 26 healthy donors were examined by a dentist,
their plasma analyzed for Hg by atomic absorption
spectrometry and for total antioxidant activity by FRAP
method. Hg plasma concentration was found to be correlated
with the number of amalgam fillings, suggesting that Hg
released from fillings is a source of Hg in non-occupational
exposed subjects. P-FRAP correlated negatively with P-Hg
suggesting a pro-oxidant role of the Hg released from
amalgam fillings. Though age by itself was not significantly
correlated with P-FRAP, when considered together with P-Hg
in multivariate analysis, it was found to be a major related
cofactor. Multivariate analysis showed no influence of fish
consumption or cigarette smoking on P-FRAP. Copyright 2002
Elsevier Science B.V.
PMID: 12493183 [PubMed - indexed for MEDLINE]
tinyurl.comcgs0Open ↗
: Bull Group Int Rech Sci Stomatol Odontol. 2000 May-Dec;42(2-3):88-
: 93.
Related Articles, Links
Salivary mercury levels in healthy donors with and without
amalgam fillings.
Pizzichini M, Fonzi M, Gasparoni A, Fonzi L.
Department of Biomedical Science, University of Siena,
Siena, Italy.
Dental amalgam (AMG) is the most diffused dental filling
material. Since it is constituted for at least 40-45% of Hg,
many questions have raised about its safe use. Hg particles
from dental amalgam dissolve in saliva and, being ingested,
they reach the blood stream through the intestinal mucosa.
It has been demonstrated that amalgam fillings continuously
release Hg vapour and that there is detectable Hg in expired
and inspired air of amalgam owners. It is not yet fully
accepted that AMG fillings represent the principal source of
Hg for man and the aim of this study was to evaluate if the
mercury level in saliva:
1) was higher within people bearing dental amalgam
restorations than in people with no restorations; 2) was
different between males or females; 3) increased in
relation to the surface of amalgam restorations. The
results showed a correlation between number of fillings
and salivary Hg, between amalgam surface and salivary Hg.
The Authors could finally assert that AMG fillings
represented the principal source of salivary Hg in the
subjects studied.
PMID: 11799732 [PubMed - indexed for MEDLINE]
tinyurl.comcgrvOpen ↗
Sci Total Environ. 2002 Feb 4;284(1-3):19-25. Related
Articles, Links
Release of mercury from dental amalgam and its influence on
salivary antioxidant activity.
Pizzichini M, Fonzi M, Sugherini L, Fonzi L, Gasparoni A,
Comporti M, Pompella
A.
Department of Biomedical Sciences, University of
Siena, Italy.
Dental amalgam fillings are known to release significant
amounts of mercury (Hg) in saliva which could represent a
continuous source of oxidative damage to mouth tissues. The
present investigation was aimed at verifying this hypothesis
by determining a possible correlation between salivary Hg
levels and salivary total antioxidant activity (TAA), which
is used as an index of oxidative stress. Samples of saliva
from 34 healthy donors were analyzed for Hg content, by
vapor atomic absorption spectrometry, and for TAA, by
determining the ferric reducing ability ('FRAP' method). A
significant correlation between Hg and the number of amalgam
restorations or total amalgam surface was evident in both
the male and female subjects. A significant negative
correlation between TAA and Hg levels or number of amalgam
restorations or amalgam surface was evident in females,
indicating that small increases in salivary Hg were
sufficient to produce a decrease in salivary TAA. On the
other hand, no significant correlation was found in the
males. The present study provides, for the first time,
evidence of a pro-oxidant role of the amalgam Hg chronically
released in saliva.
PMID: 11846163 [PubMed - indexed for MEDLINE]
tinyurl.comcgs1Open ↗
: Caries Res. 2001 May-Jun;35(3):163-6. Related
: Articles, Links
Dental amalgam fillings and the amount of organic mercury in
human saliva.
Leistevuo J, Leistevuo T, Helenius H, Pyy L, Osterblad M,
Huovinen P, Tenovuo
B.
The National Public Health Institute, Antimicrobial Research
Laboratory, Turku University, Turku, Finland.
We studied differences in the amounts of organic and
inorganic mercury in saliva samples between amalgam and
nonamalgam human study groups. The amount of organic and
inorganic mercury in whole saliva was measured in 187 adult
study subjects. The mercury contents were determined by cold-
vapor atomic absorption spectrometry. The amount of organic
and inorganic mercury in paraffin-stimulated saliva was
significantly higher (p<0.001) in subjects with dental
amalgam fillings (n = 88) compared to the nonamalgam study
groups (n = 43 and n = 56): log(e) (organic mercury) was
linearly related to log(e) (inorganic mercury, r(2) = 0.52).
Spearman correlation coefficients of inorganic and organic
mercury concentrations with the number of amalgam-filled
tooth surfaces were 0.46 and 0.27, respectively. Our results
are compatible with the hypothesis that amalgam fillings may
be a continuous source of organic mercury, which is more
toxic than inorganic mercury, and almost completely absorbed
by the human intestine.
PMID: 11385194 [PubMed - indexed for MEDLINE]
tinyurl.comcgrzOpen ↗
1: Environ Health Perspect. 2002 May;110(5):523-6. Related
Articles, Links
Inorganic mercury and methylmercury in placentas of
Swedish women.
Ask K, Akesson A, Berglund M, Vahter M.
Division of Metals and Health, Institute of Environmental
Medicine, Karolinska Institutet, Stockholm, Sweden.
We determined levels of inorganic mercury (I-Hg) and
methylmercury in placentas from 119 Swedish women, not
selected with respect to high exposure of mercury. Our
objective was to relate placental Hg species with maternal
and fetal blood concentrations and to evaluate possible
associations with selenium. We performed the analyses using
automated alkaline solubilization/reduction and cold-vapor
atomic fluorescence spectrophotometry. I-Hg levels in
placenta increased with an increasing number of maternal
dental amalgam fillings (p < .001). Despite placental
accumulation (median, 1.3 microg/kg; range, 0.18-6.7
microg/kg wet weight), a substantial fraction of maternal
blood I-Hg, probably as Hg(0), reached the fetus. Although
MeHg transferred easily to the fetus, it also accumulated in
the placenta. On average, 60% of placental Hg was in the
form of MeHg. The median concentration was 1.8 microg/kg
(range, 0-6.2 microg/kg wet weight), more than twice the
maternal blood concentration. We found significant
associations between MeHg and selenium in both maternal and
umbilical cord blood but not in the placenta. The
associations were particularly obvious in freshwater fish
consumers, probably reflecting that fish is a source of both
MeHg and selenium. We found no correlations between I-Hg and
selenium. This study increases the understanding of Hg, in
its different forms, in human placenta and how they are
related to maternal and fetal exposure.
PMID: 12003757 [PubMed - indexed for MEDLINE]
tinyurl.comcczdOpen ↗
2: Med Lav. 2002 May-Jun;93(3):139-47. Related
Articles, Links
Mercury exposure and early effects: an overview.
Kazantzis G.
Environmental Geochemistry Research Group, Department of
Environmental Science and Technology, Imperial College of
Science, Technology & Medicine, Prince Consort Road, London
SW7 2BP, UK.
OBJECTIVES: This paper was given as a keynote address at the
conference on The Assessment of the Effects Due to Low Doses
of Inorganic Mercury following Environmental and
Occupational Exposures: Human and in vitro Studies on the
Specific Mechanisms of Toxicity in Gargnano, Italy, in
September 2001. METHODS: The most relevant literature over
the past 40 years has been reviewed, and in particular, the
proceedings of the World Health Organisation conferences on
the health effects of inorganic and organic mercury exposure
have been considered. RESULTS: In an uncontaminated
environment the general population is exposed to mercury
vapour from the atmosphere and from dental amalgam, while
the diet, mainly from fish, is the principal source for
methyl mercury absorption. Mercury vapour release from
amalgam fillings increases with chewing, with absorption and
uptake by the brain and kidneys. Infants exposed to phenyl
mercury from treated diapers and young children ingesting
mercurous chloride in teething powders have developed
acrodynia (pink disease), and Kawasaki disease and the use
of mercurial skin lightening creams has been followed by the
development of the nephrotic syndrome. Both mercury
compounds and mercury vapour have given rise to contact
dermatitis in the general population. Epidemics of mercury
poisoning have followed release of mercury into the
environment from industrial activity, with uptake of methyl
mercury from fish eating in Minamata Bay and uptake of both
inorganic and methyl mercury following release of mercury
vapour and deposition into waterways from gold recovery
procedures in the Amazon basin. The ingestion of wheat and
barley seed treated with an alkyl mercury fungicide for
sowing, by a largely illiterate population in Iraq, led to a
major outbreak of poisoning with a high fatality rate.
Following exposure to mercury vapour, the earliest
clinically observed adverse effects at urine mercury levels
of the order of 30-100 mg/g creatinine, are objectively
detectable tremor, psychological disorder and impaired nerve
conduction velocity in sensitive subjects, with subjective
symptoms of irritability, fatigue and anorexia. At these and
at lower levels, proteinuria has also been observed. Both
glomerular and tubular damage may occur at exposure levels
lower than those giving rise to central nervous system
effects. An immunological effect has also been observed in
studies on clinically asymptomatic workers with low level
exposure. CONCLUSIONS: As mercury can give rise to allergic
and immunotoxic reactions which may be genetically
regulated, in the absence of adequate dose-response studies
for immunologically sensitive individuals, it has not been
possible to set a level for mercury in blood or urine below
which mercury related symptoms will not occur.
Publication Types: Lectures PMID: 12197264 [PubMed - indexed
for MEDLINE]
tinyurl.comcf81Open ↗
3: Neuroendocrinol Lett. 2003 Feb-Apr;24(1-2):65-7. Related
Articles, Links
Dental amalgam as one of the risk factors in
autoimmune diseases.
Bartova J, Prochazkova J, Kratka Z, Benetkova K, Venclikova
Z, Sterzl I.
Institute of Dental Research, lst Medical Faculty, Charles
University and General Faculty Hospital Prague, Vinohradska
48, 120 60 Prague 2, Czech Republic. [email hidden]
BACKGROUND: Experimental and clinical data published
recently show that dental amalgam can give rise to
undesirable immunological responses in susceptible
individuals. In genetically susceptible strains of
experimental animals, mercury and silver can induce
autoimmune responses. Sera of patients sensitive to mercury
were found to have a higher incidence of autoantibodies
relative to controls. OBJECTIVE: The aim of this study was
to determine possible presence of antinuclear SSB/La
autoantibodies after the in vitro stimulation of peripheral
blood lymphocytes with HgCl2. METHODS: Lymphocytes were
obtained from patients with autoimmune thyroiditis and
increased response to mercury in vitro. Mononuclear cells
were cultivated for 6 days with 100 microl HgCl2 solution or
with pure medium and the levels of antinuclear
autoantibodies SSB/La were assayed by a commercial SSB/La
ELISA kit. RESULTS: Increased production of SSB/La
autoantibodies in the media following stimulation of
peripheral blood lymphocytes with HgCl2 was found in all
cases. Using the Student's paired test, the results were
significant on the p=0.05 significance level. CONCLUSION:
Results imply that, in some patients with thyroiditis,
mercury from dental amalgam can stimulate the production of
antinuclear antibodies. Dental amalgam may be a risk factor
in some patients with autoimmune disease.
PMID: 12743535 [PubMed - indexed for MEDLINE]
Neurotoxicol Teratol. 1995 Mar-Apr;17(2):161-8. Related
Articles, Links
Behavioral effects of low-level exposure to elemental Hg
among dentists.
Echeverria D, Heyer NJ, Martin MD, Naleway CA, Woods JS,
Bittner AC Jr.
Battelle Center for Public Health Research and Evaluation
(CPHRE), Seattle, WA 98105, USA.
Exposure thresholds for health effects associated with
elemental mercury (Hg degree) exposure were examined by
comparing behavioral test scores of 19 exposed (mean urinary
Hg = 36 micrograms/l) with those of 20 unexposed dentists.
Thirty-six micrograms Hg/l is 7 times greater than the 5
micrograms Hg/l mean level measured in a national sample of
dentists. To improve the distinction between recent and
cumulative effects, the study also evaluated porphyrin
concentrations in urine, which are correlated with renal Hg
content (a measure of cumulative body burden). Subjects
provided an on-site spot urine sample, were administered a
1-h assessment consisting of a consent form, the Profile of
Mood Scales, a symptom and medical questionnaire, and 6
behavioral tests: digit-span, symbol-digit substitution,
simple reaction time, the ability to switch between tasks,
vocabulary, and the One Hole Test. Multivariate regression
techniques were used to evaluate dose-effects controlling
for the effects of age, race, gender and alcohol
consumption. A dose-effect was considered statistically
significant below a p value of 0.05. Significant urinary Hg
dose-effects were found for poor mental concentration,
emotional lability, somatosensory irritation, and mood
scores. Individual tests evaluating cognitive and motor
function changed in the expected directions but were not
significantly associated with urinary Hg. However, the
pooled sum of rank scores for combinations of tests within
domains were significantly associated with urinary Hg,
providing evidence of subtle preclinical changes in behavior
associated with Hg exposure. Coproporphyrin, one of three
urinary porphyrins altered by mercury exposure, was
significantly associated with deficits in digit span and
simple reaction time.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication Types: Clinical Trial Randomized
Controlled Trial
PMID: 7760775 [PubMed - indexed for MEDLINE]
tinyurl.com2q4akOpen ↗
euroendocrinol Lett. 2002 Oct-Dec;23(5-6):459-82. Related
Articles, Links
Removal of dental amalgam and other metal alloys
supported by antioxidant therapy alleviates symptoms and
improves quality of life in patients with amalgam-
associated ill health.
Lindh U, Hudecek R, Danersund A, Eriksson S, Lindvall A.
Department of Oncology, Radiology and Clinical Immunology,
Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.
[email hidden]
OBJECTIVES: The purpose of this study was to evaluate
treatment of patients suffering from chronic ill health with
a multitude of symptoms associated with metal exposure from
dental amalgam and other metal alloys. SETTING AND DESIGN:
We included 796 patients in a retrospective study using a
questionnaire about symptom changes, changes in quality of
life as a consequence of treatment and assessment of care
taking. METHODS: Treatment of the patients by removal of
offending dental metals and concomitant antioxidant therapy
was implemented according to the Uppsala model based on a
close co-operation between physicians and dentists. RESULTS:
More than 70% of the responders, remaining after exclusion
of those who had not begun or completed removal, reported
substantial recovery and increased quality of life.
Comparison with similar studies showed accordance of the
main results. Plasma concentrations of mercury before and
after treatment supported the metal exposure to be causative
for the ill health. MAIN FINDINGS: Treatment according to
the Uppsala model proved to be adequate for more than 70% of
the patients. Patients with a high probability to respond
successfully to current therapy might be detected by symptom
profiles before treatment. CONCLUSIONS: The hypothesis that
metal exposure from dental amalgam can cause ill health in a
susceptible part of the exposed population was supported.
Further research is warranted to develop laboratory tests to
support identification of the group of patients responding
to current therapy as well as to find out causes of problems
in the group with no or negative results.
PMID: 12500173 [PubMed - indexed for MEDLINE]
tinyurl.comyqwleOpen ↗
4: Aust Dent J. 2000 Dec;45(4):224-34. Related
Articles, Links
Comment in: Aust Dent J. 2001 Mar;46(1):60-1. Dental amalgam
and mercury in dentistry.
Spencer AJ.
Dental School, University of Adelaide.
Mercury in dentistry has re-emerged as a contentious issue
in public health, predominantly because so many people are
inadvertently exposed to mercury in order to obtain the
benefits of dental amalgam fillings, and the risks remain
difficult to interpret. This commentary aims to examine the
issues involved in public policy assessment of the continued
use of dental amalgam in dentistry. More than 30 per cent of
Australian adults are concerned about mercury from dental
amalgam fillings but only a small percentage report having
their amalgam fillings removed. The placement of dental
fillings nearly halved between 1983 and 1997, but many
millions of dental amalgam fillings exist in the Australian
community. These fillings release mercury (mercury vapour or
inorganic ions) at a low level (about 2-5 micrograms/day in
an adult). Evidence on the health effect of dental amalgams
comes from studies of the association between their presence
and signs or symptoms of adverse effects or health changes
after removal of dental amalgam fillings. More formal risk
assessment studies focus on occupational exposure to mercury
and health effects. Numerous methodological issues make
their interpretation difficult but new research will
continue to challenge policymakers. Policy will also reflect
prudent and cautious approaches, encouraging minimization of
exposure to mercury in potentially more sensitive population
groups. Wider environmental concerns and decreasing
tolerance of exposure to other mercury compounds (for
example, methylmercury in seafoods) will ensure the use of
mercury in dentistry remains an issue, necessitating
dentists keep their patients informed of health risks and
respect their choices.
Publication Types: Review Review, Tutorial PMID: 11225523
[PubMed - indexed for MEDLINE]
tinyurl.com3f48xOpen ↗
5: FASEB J. 1998 Aug;12(11):971-80. Related Articles, Links
Neurobehavioral effects from exposure to dental amalgam
Hg(o): new distinctions between recent exposure and Hg
body burden.
Echeverria D, Aposhian HV, Woods JS, Heyer NJ, Aposhian MM,
Bittner AC Jr, Mahurin RK, Cianciola M.
Battelle Centers for Public Health Research and Evaluation,
Seattle, Washington 98105, USA.
Potential toxicity from exposure to mercury vapor (Hg(o))
from dental amalgam fillings is the subject of current
public health debate in many countries. We evaluated
potential central nervous system (CNS) toxicity associated
with handling Hg-containing amalgam materials among dental
personnel with very low levels of Hg(o) exposure (i.e.,
urinary Hg <4 microg/l), applying a neurobehavioral test
battery to evaluate CNS functions in relation to both recent
exposure and Hg body burden. New distinctions between subtle
preclinical effects on symptoms, mood, motor function, and
cognition were found associated with Hg body burden as
compared with those associated with recent exposure. The
pattern of results, comparable to findings previously
reported among subjects with urinary Hg >50 microg/l,
presents convincing new evidence of adverse behavioral
effects associated with low Hg(o) exposures within the range
of that received by the general population.
PMID: 9707169 [PubMed - indexed for MEDLINE]
