Well, what about this explanation:
High TG and low HDL indicates insulin resistance. The most
obvious symptom of insulin resistance is of course highly
increased insulin levels in blood and unstable blood sugar.
Both are highly atherogenic.
So maybe TG/HDL ration is nothing else than indicator of
insulin resistance. As TG and HDL are related with general
dislipidemia and high TC as well, it would simply explain
most results of Farmingham stdies, failed results of non-
statin TC reduction drugs, failed results of low-fat mania
etc, etc...
In this context low-carb would indeed be benefical, as it
should improve both BG stability and reduce insulin
secretion - and this would be demonstrated in improved TG
and HDL levels.
As for dr. Chung's (and Barry Sear's) concerns about lipid
peroxidation due to ketonemia, well, in very deep ketosis or
ketoacidosis it really might happen. In any case it is
better to stay away from deep ketosis and to suplement with
E vitamin to prevent peroxidation.
Speaking about it, many consider The Zone to be the low-carb
plan. South-Beach promotes itself as non-ketogenic from the
day one. Atkins is ketogenic, but when followed as written
it should lead you on the "edge" of ketosis (around 50g
carbs a day). That is as ketogenic as fasting for 24 hours.
Mirek
"Susan " <
[email protected]> pí¹e v diskusním pøíspìvku
news:[email protected]...
> x-no-archive: yes
>
> >Does the substantial reduction in trigylcerides in the
> >blood from
following
> >a low-carb eating plan (about 50% fat calories, 25%
> >protein calories,
25%
> >low-glycemic carbohydrate calories) result in a decreased
> >long-term
risk for
> >heart disease? Blood lipid tests pretty clearly show
> >triglycerides
reducing
> >by about half on average for most people. I want to
> >know the
implications of
> >this over the long haul.
> >
> >Thanks!
> >
> >-Chad
>
> Triglycerides are an independent risk factor, some
> researchers believe
TGL to
> be a more accurate predictor of CVD:
>
> "A new study suggests that level of triglyceride in the
> blood may help predict heart attack risk as well as other
> more well-known blood fats such as LDL and HDL
> cholesterol. High triglycerides alone increased the risk
> of heart attack nearly three-fold, according to a report
> in the current issue of Circulation. And people with the
> highest ratio of triglycerides to HDL -- the "good"
> cholesterol -- had 16 times the risk of heart attack as
> those with the lowest ratio of triglycerides to HDL in the
> study of 340 heart attack patients and 340 of their
> healthy, same age counterparts. The ratio of triglycerides
> to HDL was the strongest predictor of a heart attack, even
> more accurate than the
> LDL/HDL ratio," reported Harvard lead study author.
> Triglycerides, a mixture of fatty acids and glycerol
> that make up the principle fats in the blood, bind to
> carrier proteins, forming compounds known as
> lipoproteins. Other types of lipoproteins that carry
> cholesterol, such as LDL and HDL, are known to be
> related to the risk of heart disease because of their
> propensity to deposit -- or not deposit -- fat in
> coronary arteries. However, it has not been clear if
> triglyceride level could predict heart attack risk,
> despite years of research." Circulation (1997;96:2520-
> 2525)
>
> Susan
