Discussion in 'Health and medical' started by Dr. Jai Maharaj, Jul 2, 2003.

  1. New way to keep stroke at bay

    The Times of India
    Wednesday, July 2, 2003

    Washington - Latest research may soon pave the way for
    more effective prevention of stroke. An experiment on
    rats has successfully proved that a new non-invasive way
    can help keep stroke at bay.

    The method involves injecting a stimulant agent into rat
    brains. This expanded blood vessels and improved blood
    flow, researchers reported in the rapid access issue of
    Circulation: Journal of the American Heart Association.

    Rats treated with the growth-promoting substance
    granulocyte macrophage-colony stimulating factor (GM-CSF)
    had almost twice as much arteriogenesis, the expansion of
    a brain artery, after one week compared to rats given
    saline solution. The increase was associated with
    improved circulation and accumulation of cells that are
    thought to play a key role in artery development.

    "To the best of our knowledge, this is the first report
    of stimulation of arteriogenesis in the brain," say co-
    lead authors Ivo R Buschmann and Hans-Jvrg Busch. Both
    are investigators in the Research Group for Experimental
    and Clinical Arteriogenesis at Albert Ludwigs University
    in Freiburg, Germany.

    The findings suggest that growth-stimulating substances
    may be a novel alternative to other stroke prevention
    strategies, which tend to emphasise surgery and other
    invasive techniques that improve blood flow to the
    brain, the researchers say.

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