Pernicious Anemia / iron overload protection



Rev Med Interne. 2004 Oct;25(10):759-61. Related Articles, Links


[Association of hereditary hemochromatosis and pernicious anaemia]

[Article in French]

Attout H, Guez S, Series C.

Service de medecine interne, CHR Pellegrin, place Raba-Leon, 33000
Bordeaux, France. [email protected]

INTRODUCTION: Hereditary hemochromatosis is inherited as an autosomal
recessive trait. It is characterized by increased absorption of dietary
iron. The association between pernicious anaemia and hereditary
hemochromatosis has never been described. EXEGESIS: We report a case of
paradoxical association of hereditary hemochromatosis and pernicious
anaemia. CONCLUSION: It seems that pernicious anaemia may prevent
manifestations of hemochromatosis. We suppose that this protective role
is due to atrophic body gastritis with iron malabsorption.

PMID: 15471603 [PubMed - indexed for MEDLINE]

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