Pernicious Anemia / iron overload protection

Discussion in 'Food and nutrition' started by [email protected], Mar 12, 2005.

  1. Rev Med Interne. 2004 Oct;25(10):759-61. Related Articles, Links

    [Association of hereditary hemochromatosis and pernicious anaemia]

    [Article in French]

    Attout H, Guez S, Series C.

    Service de medecine interne, CHR Pellegrin, place Raba-Leon, 33000
    Bordeaux, France. [email protected]

    INTRODUCTION: Hereditary hemochromatosis is inherited as an autosomal
    recessive trait. It is characterized by increased absorption of dietary
    iron. The association between pernicious anaemia and hereditary
    hemochromatosis has never been described. EXEGESIS: We report a case of
    paradoxical association of hereditary hemochromatosis and pernicious
    anaemia. CONCLUSION: It seems that pernicious anaemia may prevent
    manifestations of hemochromatosis. We suppose that this protective role
    is due to atrophic body gastritis with iron malabsorption.

    PMID: 15471603 [PubMed - indexed for MEDLINE]

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