Questions on salt diuresis

Mxsmanic said:

Yesterday I noticed that I produced considerably more
urine than usual, for no immediately obvious reason... I
recalled that I had eaten two bags of salty corn chips
about 48 hours earlier.

Generally speaking, sodium ingestion will stimulate thirst,
which will encourage fluid consumption, which may result in
subsequent diuresis. That's about the best explanation I can
offer (I'm no nephrologist).

Mxsmanic <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

I know that high salt intake can have a diuretic effect,
since the body attempts to restore sodium balance by
excreting extra salt in the urine,

Salt affects diuretic balance, it removes fluid out of body
via urinating. Your body is drier with higher concentration
of sodium, with higher blood pressure.

Experiment: cook 2 similar steaks, one with heavy salty
seasoning, one
w/o salt. The one with salt is drier and cooked faster (by
releasing more juice, a temperature regulator). The other
steak, more juicy and pinkier when cooked at the same temp
and duration.

How salt affects high blood pressure? Your brain tries to
restore pre-programmed fluid balance by contricting blood
vessels to creater higher internal pressure to get kidney
released more urine (with salt) out to the body, thus
creates higher blood pressure.

(Unqualified observation)

Mxsmanic <[email hidden]> wrote in message news:<[email hidden]>...

Quoted message said:

I know that high salt intake can have a diuretic effect,
since the body attempts to restore sodium balance by
excreting extra salt in the urine, but how long does it
take for this diuresis to become apparent?

Depends on kidney function. Typically about a day.

Quoted message said:

Yesterday I noticed that I produced considerably more
urine than usual, for no immediately obvious reason. After
considerable reflection, I recalled that I had eaten two
bags of salty corn chips about 48 hours earlier. I know
from past experience that some sort of diuresis often
follows consumption of a large amount of salt in my case,
usually after a delay of a day or so (once I stop eating
the salt). I don't normally consume any salt, and I never
add salt to anything, but sometimes I see this effect when
I eat very salty foods (potato chips, popcorn).

My question is this: If this diuresis occurs to get rid of
salt, why is it delayed by a day or more?

Diuresis gets rid of *both* sodium and water. By itself,
sodium is not a diuretic.

Quoted message said:

Wouldn't it occur within hours?

Depends on fluid intake and kidney function (and
bladder size :-).

Quoted message said:

The link to salty foods seems pretty consistent; it has
happened on many occasions. I eat lots of Fritos one day,
and the evening of the following day (for example) I
produce more urine than usual, even though I may not be
eating or drinking anything.

The latter may be occurring from hyperketonemia (from
fasting) having a diuretic effect. Usually, increased sodium
intake does result in increased water intake (including
water in foods).

Quoted message said:

Can someone enlighten me on the exact connection between
temporary, high salt intake and any resulting diuresis?

The exact connection resides in the kidneys "sensing"
intravascular volume.

Quoted message said:

How does it work, exactly, and
why does it seem to be deferred?

The ZG cells in the nephrons of the kidneys are sensitive to
the blood pressure in the afferent arterioles and release
renin when the blood pressure is low. Renin (among other
things) converts angiotensinogen to angiotensin I, which
becomes angiotensin II thanks to peripheral ACE. Angiotensin
II is powerful peptide hormone that causes arteriolar
vasocontriction thereby raising blood pressure. It also
antagonizes diuresis. Renin also elevates aldosterone which
has antidiuretic properties because it cause the kidneys to
hold on to salt (sodium). It does take some time for these
"brakes" to be released with there is a salt load from
dietary intake. Also, it does take time for the bladder to
fill (for some sooner than others :-).

Hope this helps you.

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
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