Someone was saying that randomness was a big part of
molecular biology. I responded that it may be less than we
think because these random changes must happen in a non
random environment. Specifically a temperature range that
only allows for chemistry at that temperature.
Let's go further with 2 examples.
Let's say you have a beaker that heats up from 50 C for 5
hours, then lowers for 5. And repeats endlessly. There may
be random molecular changes, but they will be within the
chemistry of that temperature range.
And the variants from say the fluctuating temp on the edge
of a star, would be random too, but they too would not
exceed the reasonable bounds of the chemistry of temperature
in that range.
Thus random changes must exist within the non random
chemistry boundaries of that environment. So there is
randomness - but it is far from open ended randomness. It
has strict boundaries in that randomness.