General fitness, health and nutrition · Public discussion

Re: Clembuteral Side Effects

Started by bobbie · · Last activity · 1 post · 557 views

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General fitness, health and nutrition
Published
10 March 2006
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  1. Where can I get some?

    "Beach Runner" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    Clenbuterol is a popular - but banned - drug used by athletes in
    body-building, power-related, and even endurance sports. The chemical is
    attractive to athletes because it appears to have an anabolic effect on
    human muscles, and it may also increase fat metabolism. However, the
    actual effects of long-term clenbuterol intake on performance, muscle
    power, and overall health have been unclear.

    To determine some of clenbuterol's actions, scientists at the University
    of Melbourne in Australia recently gave clenbuterol to laboratory rats at
    dosages of 2 milligrams per kilogram of body weight per day. Some of the
    rats followed a completely sedentary lifestyle, while others sprinted on
    treadmills or engaged in endurance swim training. Clenbuterol did have a
    couple of potentially positive effects: Sedentary rats which ingested
    clenbuterol had larger muscles than clenbuterol-free, sedentary rodents,
    and clenbuterol users also transformed leg-muscle cells from slow-twitch
    to fast-twitch fibres, a surprising change which would tend to increase
    anaerobic energy production and magnify muscle power during short, intense
    exertions.

    However, clenbuterol also yielded three very negative changes. First,
    after just four weeks, clenbuterol-treated rats were unable to maintain
    their normal swimming or running training intensities, while clean rodents
    were quite capable of continuing. Secondly, the hearts of the
    clenbuterol-taking, trained rats increased dramatically in size compared
    to the hearts of sedentary rats, but the heart expansion was probably due
    to the infiltration of collagen fibres into the heart walls, not an
    increase in heart-muscle cells. Collagen is a tough connective tissue
    which doesn't augment heart-muscle power but in fact stiffens the heart,
    potentially leading to a decrease in cardiac output. Increases in collagen
    may also produce cardiac arrhythmias. Thirdly, clenbuterol rats suffered
    from noticeable cardiac-cell degeneration.

    In addition, although sedentary, clenbuterol-treated rats were more
    muscular than clenbuterol-free, sedentary rats, clenbuterol was unable to
    boost muscle mass among either the swim- or treadmill-trained rodents. It
    appears that, in spite of its popularity, clenbuterol is a potentially
    dangerous drug which offers very few positive effects for either the power
    or endurance athlete.

    ('The Effects of Clenbuterol on Skeletal and Cardiac Muscle of Rats when
    Combined with Aerobic and Anaerobic Exercise, ' Biochemistry of Exercise
    Ninth International Conference Abstracts, #117, p 75, 1994)

    clenbuterol side effects

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