A
Alf Christophersen
Guest
On Sat, 25 Mar 2006 00:12:08 +0200, Matti Narkia <[email protected]> wrote:
>Fri, 24 Mar 2006 12:41:57 -0700 in article
><[email protected]> "vernon"
><[email protected]> wrote:
>
>>Cholesterol feeds the brain. For those who have none (brain) it's a
>>problem.
>>
>Cholesterol intake and serum cholesterol are irrelavant for brain's
>cholseterol requirements, because cholesterol cannot get across
>blood-brain barrier, brain makes its own cholesterola. Moreover, high
>dietary or serum cholesterol seems to down-regulate brain's cholesterol
>synthesis. References:
Possibly are some of the feedback signal molecules also transported
over the brain barriere giving downtuning signals even in brain.
Perhaps not a good idea.
Just a wild guess based on knowledge about regulation theory and
enzyme kinetics back in biochemistry study (I worked with enzyme
kinetics and even tried to do simulations of regulated systems, but
computers was not good enough at that time, and the computer that
could have solved it was far to expensive to use for my thesis. So I
gave up that part of my thesis, together with a nearly finished
protein sequence program which would otherwise have been the very
first published in that area of biochemistry to my knowledge, but they
changed the computer a few week before and Simula 67 was not among the
compilers supported anymore on that new DEC VAX computer (in 1983)
:-(
But then DNA sequencing took over, anyway)
>Fri, 24 Mar 2006 12:41:57 -0700 in article
><[email protected]> "vernon"
><[email protected]> wrote:
>
>>Cholesterol feeds the brain. For those who have none (brain) it's a
>>problem.
>>
>Cholesterol intake and serum cholesterol are irrelavant for brain's
>cholseterol requirements, because cholesterol cannot get across
>blood-brain barrier, brain makes its own cholesterola. Moreover, high
>dietary or serum cholesterol seems to down-regulate brain's cholesterol
>synthesis. References:
Possibly are some of the feedback signal molecules also transported
over the brain barriere giving downtuning signals even in brain.
Perhaps not a good idea.
Just a wild guess based on knowledge about regulation theory and
enzyme kinetics back in biochemistry study (I worked with enzyme
kinetics and even tried to do simulations of regulated systems, but
computers was not good enough at that time, and the computer that
could have solved it was far to expensive to use for my thesis. So I
gave up that part of my thesis, together with a nearly finished
protein sequence program which would otherwise have been the very
first published in that area of biochemistry to my knowledge, but they
changed the computer a few week before and Simula 67 was not among the
compilers supported anymore on that new DEC VAX computer (in 1983)
:-(
But then DNA sequencing took over, anyway)