And what exactly are we to make of this, how does it relate to any body of
theory, to what practical use is it, and toward what goal can it be
applied? Without this information it is but another random abstract
plucked from the web, one among thousands of such.
Quoted message said:The snip tells the tale .. the USUAL method failed to assess iron parameters
correctly allowing for the doctors to give her iron until it .. seems to ..
almost .. kill .. her ..<<snip>>
The
routine method for determining serum Fe concentration in our hospital is direct
photoscopic assay. When we assayed serum Fe concentration by a deproteinization
method, it showed a higher value
<<snip>>Rinsho Byori. 2000 Aug;48(8):730-3. Related Articles, Links
[A case of hemophagocytosis syndrome with excessive Fe and ferritin
concentration in serum and with a good prognosis][Article in Japanese]
Maekawa M, Hara K.
Clinical Laboratory, National Cancer Center Hospital, Tokyo.
Investigation in the present case began with a high serum Fe concentration. The
routine method for determining serum Fe concentration in our hospital is direct
photoscopic assay. When we assayed serum Fe concentration by a deproteinization
method, it showed a higher value. We also measured serum ferritin
concentration, and suspected that high ferritin interfered with serum Fe
concentration. We checked the dose-dependent effect of ferritin on serum Fe
determination. The present case, a 64-year-old female, showed a reduction of
Plt count, and an elevation of LDH, CRP and so on, meeting most of the criteria
for hemophagocytosis syndrome. Bone marrow smears revealed phagocytosis of
blood cells. The present case had been followed for rheumatoid arthritis and
medicated with oral iron pills. In her liver and spleen, high amounts of Fe had
accumulated, and excessive Fe was being released into the blood by any trigger,
such as infection, stress, cytokine activation, and/or HPS.Publication Types:
Case ReportsPMID: 11064596 [PubMed - indexed for MEDLINE]
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Tom
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