General fitness, health and nutrition · Public discussion

Re: Stain-Associated Memory Loss

Started by Sharon Hope · · Last activity · 2 posts · 336 views

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General fitness, health and nutrition
Published
9 August 2003
Last activity
10 August 2003
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Sharon Hope
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  1. "Don Kirkman" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:
    Quoted message said:
    Quoted message said:

    "About 2% of statin-associated adverse events had a cognitive


    identifier

    Quoted message said:
    Quoted message said:
    Quoted message said:

    (cognitive, attentional, or amnestic disorder)."

    How many were in the total population from which these 60 cases of
    memory loss and 25,000 adverse events (presumably some patients may have
    had more than one adverse event) were drawn?

    To quote Dr. Faxon, co-author of the joint advisory on statin safety issued
    by the American College of Cardiology and the American Heart Association,
    shortly after Baycol was pulled. In the context of our conversation that
    indicated this adverse effect was known, was thought to be rare, and that
    there is no way known to screen patients to prevent the succeptible from
    having their memory destroyed, and that there is no known treatment. He
    said to me,

    "How rare the condition is does not make any difference if, in your family,
    it is 100%."

    Quoted message said:

    --
    Don
    [email hidden]

  2. "Don Kirkman" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    It seems to me I heard somewhere that Sharon Hope wrote in article
    <9H7Za.70871$cF.22719@rwcrnsc53>:

    Quoted message said:

    "Don Kirkman" <[email hidden]> wrote in message
    news:[email hidden]...

    There is such a thing as enlightened risk
    aversion as well as obsessive risk aversion.

    Absolutely - ENLIGHTENED risk aversion. Do a search on the NIH pub med site
    on the terms "statin" and "memory" and see how many hits you get: 1

    There is no ENLIGHTENED acknowledgement of the side effect in the US, and
    therefore no patient is aware they are taking the risk. Worse, their
    doctors are also unaware, and therefore they don't watch for it, nor do they
    consider it a reason for discontinuing the drug.

    Australia's FDA-equivalent recognized memory loss is associated with statins
    and published it as a known adverse effect in 1998.

    Quoted message said:

    Could Dr. Faxon have been talking specifically about Baycol, which as we
    all know did have problems and is no longer available, and not of
    statins as a class?

    Dr. Faxon was talking to me about my husband, disabled by Lipitor. A 55
    year old man, twice a CEO, who after 4 years of Lipitor scores BELOW the 1
    percentile in short-term memory (along with a long list of other adverse
    effects, including myopathy, myositis, peripheral neuropathy, aphasia, and
    multiple on-Lipitor Transient Global Amnesia events, muscle wasting, and
    extreme exercise intolerance.) My husband, who like many many others, did
    not recover by merely discontinuing the drug, and still is disabled 19
    months off the drug.

    Not Baycol, not generalities, not enlightened risk taking, my husband of 34+
    years.

    It is my home and my family he was referring to when he said it did not
    matter how rare these KNOWN (but not well documented) adverse effects are,
    if they happen to your family they are 100%.

    The point is that people need to know to make ENLIGHTENED risk decisions.
    Not addresing the problem, not developing a method of screening out patients
    who are candidates for disability, not developing a treatment is not
    supporting decisions of risk. It is unconscionable.

    Quoted message said:

    --
    Don
    [email hidden]

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