Yes, it could do so but probably only at extremes. Be very careful of rigidly sticking to the set-up 'standards' many will talk about. Proper bike fit, and particularly seat set-back, is about tuning the bike to your body's functional capability. The extreme majority of people (I'm talking road racing here) will be better off with the front of knee behind the pedal spindle. Often this may be as much as 20mm. Similarly, the cleat position you use, because it affects the functional 'lever length' applied by your foot, is just as critical. Study some photos of Pros and, ignoring the large seat/bar height discrepancy they can get away with, you'll see that none of them are anywhere near the mythical knee over spindle standard. All other things being equal, the higher and further back you can sit, the more power you will generate. The catch is finding the extreme which your physiology can live with in not stressing any one muscle group and which your age/flexibility can allow you to pedal comfortably. No easy task to get it right but play with it - in small increments - and you'll see benefits. I guess the easy route is to get a pro fit by someone who examines your functional capability and not just some standard formula. Remember, even then, that as you age or get injuries etc your functional abilities change and you should try to be alert to what your body tells you (pain, reducing strength etc) and adjust accordingly.