Scientists discover sugar controlling molecules in mice PTI Thursday, August 7, 2003 Indraprasth - Scientists in the United States have discovered a molecule which has been found to lower the blood sugar levels in diabetic mice, a development which may help controlling diabetes in future. A team of scientists led by Joseph Grippo and Joseph Grimsby at the Hoffmann-La Roche in New Jersey discovered a molecule which activates an enzyme called 'glucokinase'. The enzyme is important in the manifestation of diabetes. The researchers tested the activator on islet cells, the pancreatic cells that secrete insulin. The drug coaxed rat islet cells to release insulin even when glucose levels were not that high. It could help diabetics who produce too little of insulin, a report in journal Science said. The drug acted on the rat liver cells too. When exposed to the drug, they released less glucose than usual, easing another major problem of diabetes patients, the report said. Further studies confirmed that the activator was targeting glucokinase in both pancreatic and liver cells. Insulin is a hormone that shuttles glucose into cells. When the pancreas produces too little insulin or the body does not respond to it properly, cells do not absorb enough glucose and blood sugar levels go high. There is no perfect therapy for this condition, but most drugs tackle the problem either by increasing insulin production or enhancing cell's sensitivity to insulin. In severe cases, patients rely on insulin injection, it said. The condition damages blood vessels and other tissues, the report said. Read the complete news at: http://www.timesofindia.com News Plus http://www.mantra.com/newsplus Jai Maharaj http://www.mantra.com/jai Om Shanti Panchaang for 10 Shravan 5104, Thursday, August 7, 2003: Shubhanu Nama Samvatsare Dakshinaya Nartana Ritau Kark Mase Shukl Pakshe Guru Vasara Yuktayam Jyeshtth Nakshatr Indr-Vaidhruti Yog Vanij-Vishti Karan Ekadashi Yam Tithau Hindu Holocaust Museum http://www.mantra.com/holocaust Hindu life, principles, spirituality and philosophy http://www.hindu.org http://www.hindunet.org The truth about Islam and Muslims http://www.flex.com/~jai/satyamevajayate o Not for commercial use. Solely to be fairly used for the educational purposes of research and open discussion. The contents of this post may not have been authored by, and do not necessarily represent the opinion of the poster. The contents are protected by copyright law and the exemption for fair use of copyrighted works. o If you send private e-mail to me, it will likely not be read, considered or answered if it does not contain your full legal name, current e-mail and postal addresses, and live-voice telephone number. o Posted for information and discussion. Views expressed by others are not necessarily those of the poster.