Statin Haters Alert



B

Brad Sheppard

Guest
Lipitor stops progression of plaque buildup. Don't let this newsgroup
scare you from taking statins. "Patients taking Pfizer Inc's
cholesterol-lowering medicine Lipitor (atorvastatin calcium)
experienced a significant reduction in the progression of
atherosclerosis, or hardening of the arteries, compared to patients
who received Pravachol (pravastatin), according to new data presented
today at the annual meeting of the American Heart Association."
http://www.pfizer.com/are/news_releases/mn_2003_1112.html
 
On 12 Nov 2003 08:16:50 -0800, [email protected] (Brad
Sheppard) wrote:

>Lipitor stops progression of plaque buildup. Don't let this newsgroup
>scare you from taking statins. "Patients taking Pfizer Inc's
>cholesterol-lowering medicine Lipitor (atorvastatin calcium)
>experienced a significant reduction in the progression of
>atherosclerosis, or hardening of the arteries, compared to patients
>who received Pravachol (pravastatin), according to new data presented
>today at the annual meeting of the American Heart Association."
>http://www.pfizer.com/are/news_releases/mn_2003_1112.html


I don't see how I could take 80mgs of Lipitor daily. I tried taking
20mg Lipitor a few years ago and experienced severe leg cramps, so I
went back to Pravachol. Guess I'm stuck.

You're right though - more fodder for the statin wars.
 
"Brad Sheppard" <[email protected]> wrote in message
news:[email protected]...
> Lipitor stops progression of plaque buildup. Don't let this newsgroup
> scare you from taking statins. "Patients taking Pfizer Inc's
> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
> experienced a significant reduction in the progression of
> atherosclerosis, or hardening of the arteries, compared to patients
> who received Pravachol (pravastatin), according to new data presented
> today at the annual meeting of the American Heart Association."
> http://www.pfizer.com/are/news_releases/mn_2003_1112.html

How do statins compare to Aspirin? Both statins and Aspirin are anti
imflamatories. Aspirin probably does not reduce Cholesterol but cholesterol
has not been shown to "Cause" atherosclerosis. Half of people with CAD have
average or below average cholesterol.
 
On Wed, 12 Nov 2003 12:20:55 -0500, [email protected] wrote:

>On 12 Nov 2003 08:16:50 -0800, [email protected] (Brad
>Sheppard) wrote:
>
>>Lipitor stops progression of plaque buildup. Don't let this newsgroup
>>scare you from taking statins. "Patients taking Pfizer Inc's
>>cholesterol-lowering medicine Lipitor (atorvastatin calcium)
>>experienced a significant reduction in the progression of
>>atherosclerosis, or hardening of the arteries, compared to patients
>>who received Pravachol (pravastatin), according to new data presented
>>today at the annual meeting of the American Heart Association."
>>http://www.pfizer.com/are/news_releases/mn_2003_1112.html
>
>
>I don't see how I could take 80mgs of Lipitor daily. I tried taking
>20mg Lipitor a few years ago and experienced severe leg cramps, so I
>went back to Pravachol.
Same here!! High dose Lipitor was a disaster for me. I felt like i was
beat with a club. No way i'd come near that again.
>You're right though - more fodder for the statin wars.
Getting serious when they start buying research to show they are
better then their competition. So much for good research.
ken
 
On 12 Nov 2003 08:16:50 -0800, Brad Sheppard <[email protected]>
wrote:

> Lipitor stops progression of plaque buildup. Don't let this newsgroup
> scare you from taking statins. "Patients taking Pfizer Inc's
> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
> experienced a significant reduction in the progression of
> atherosclerosis, or hardening of the arteries, compared to patients
> who received Pravachol (pravastatin), according to new data presented
> today at the annual meeting of the American Heart Association."
> http://www.pfizer.com/are/news_releases/mn_2003_1112.html
>

I agree that statins should be considered in an overall treatment against
atherosclerosis

http://tinyurl.com/uq5f

Curr Med Res Opin. 2003;19(6):540-56. Early vascular benefits of statin
therapy.
Tsiara S, Elisaf M, Mikhailidis DP.
Internal Medicine Department, University of Ioannina Medical School,
Ioannina, Greece.

....A significant reduction of the carotid intima media thickness (IMT) was
also reported early after statin treatment...

--
~~~
Patrick Blanchard, M.D., A.B.F.P.
Board Certified in Family Practice
http://www.familydoctor.org/blanchard
 
On Wed, 12 Nov 2003 12:22:22 -0500, Paul E. Lehmann
<[email protected]> wrote:

>
> "Brad Sheppard" <[email protected]> wrote in message
> news:[email protected]...
>> Lipitor stops progression of plaque buildup. Don't let this newsgroup
>> scare you from taking statins. "Patients taking Pfizer Inc's
>> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
>> experienced a significant reduction in the progression of
>> atherosclerosis, or hardening of the arteries, compared to patients
>> who received Pravachol (pravastatin), according to new data presented
>> today at the annual meeting of the American Heart Association."
>> http://www.pfizer.com/are/news_releases/mn_2003_1112.html
>
> How do statins compare to Aspirin? Both statins and Aspirin are anti
> imflamatories. Aspirin probably does not reduce Cholesterol but
> cholesterol
> has not been shown to "Cause" atherosclerosis. Half of people with CAD
> have
> average or below average cholesterol.
>
>
>
>
This is a great question, so I did some www.pubmed.gov searching and came
up with an interesting study.

Aspirin has been shown to 'attenuate' or increase the rate of carotid
intima media thickness (CIMT) regression in type 2 diabetics. As to how it
does this, and if this mechanism is similar to the statin, I don't know.

http://tinyurl.com/uq7c

Antiplatelet drugs attenuate progression of carotid intima-media thickness
in subjects with type 2 diabetes.
Thromb Res. 2000 Feb 15;97(4):239-45.

Thanks for spurring this thread!


--
~~~
Patrick Blanchard, M.D., A.B.F.P.
Board Certified in Family Practice
http://www.familydoctor.org/blanchard
 
On Wed, 12 Nov 2003 12:22:22 -0500, "Paul E. Lehmann"
<[email protected]> wrote:

>
>"Brad Sheppard" <[email protected]> wrote in message
>news:[email protected]...
>> Lipitor stops progression of plaque buildup. Don't let this newsgroup
>> scare you from taking statins. "Patients taking Pfizer Inc's
>> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
>> experienced a significant reduction in the progression of
>> atherosclerosis, or hardening of the arteries, compared to patients
>> who received Pravachol (pravastatin), according to new data presented
>> today at the annual meeting of the American Heart Association."
>> http://www.pfizer.com/are/news_releases/mn_2003_1112.html
>
>How do statins compare to Aspirin? Both statins and Aspirin are anti
>imflamatories. Aspirin probably does not reduce Cholesterol but cholesterol
>has not been shown to "Cause" atherosclerosis. Half of people with CAD have
>average or below average cholesterol.
They just spent a lot of money to show Lipitor was better than a
competing statin. You are going to ruin their whole plan by bringing
up another alternative that is dirt cheap compared to their competing
statin. Remember it is their market share that is most important. Get
the patients money.
ken
 
"Patrick Blanchard, M.D." <[email protected]> wrote in part:

>On 12 Nov 2003 08:16:50 -0800, Brad Sheppard <[email protected]>
>wrote:
>
>> Lipitor stops progression of plaque buildup. Don't let this newsgroup
>> scare you from taking statins. "Patients taking Pfizer Inc's
>> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
>> experienced a significant reduction in the progression of
>> atherosclerosis, or hardening of the arteries, compared to patients
>> who received Pravachol (pravastatin), according to new data presented
>> today at the annual meeting of the American Heart Association."
>> http://www.pfizer.com/are/news_releases/mn_2003_1112.html
>>
>
>I agree that statins should be considered in an overall treatment against
>atherosclerosis
>
>http://tinyurl.com/uq5f
>
>Curr Med Res Opin. 2003;19(6):540-56. Early vascular benefits of statin
>therapy.
>Tsiara S, Elisaf M, Mikhailidis DP.
>Internal Medicine Department, University of Ioannina Medical School,
>Ioannina, Greece.
>
>...A significant reduction of the carotid intima media thickness (IMT) was
>also reported early after statin treatment...

Anyone have the full text and know which statins were used in the study?
--
Jim Chinnis Warrenton, Virginia, USA
 
On Wed, 12 Nov 2003 10:38:25 -0800, [email protected] wrote:

>On Wed, 12 Nov 2003 12:22:22 -0500, "Paul E. Lehmann"
><[email protected]> wrote:
>
>>
>>"Brad Sheppard" <[email protected]> wrote in message
>>news:[email protected]...
>>> Lipitor stops progression of plaque buildup. Don't let this newsgroup
>>> scare you from taking statins. "Patients taking Pfizer Inc's
>>> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
>>> experienced a significant reduction in the progression of
>>> atherosclerosis, or hardening of the arteries, compared to patients
>>> who received Pravachol (pravastatin), according to new data presented
>>> today at the annual meeting of the American Heart Association."
>>> http://www.pfizer.com/are/news_releases/mn_2003_1112.html
>>
>>How do statins compare to Aspirin? Both statins and Aspirin are anti
>>imflamatories. Aspirin probably does not reduce Cholesterol but cholesterol
>>has not been shown to "Cause" atherosclerosis. Half of people with CAD have
>>average or below average cholesterol.
>They just spent a lot of money to show Lipitor was better than a
>competing statin. You are going to ruin their whole plan by bringing
>up another alternative that is dirt cheap compared to their competing
>statin. Remember it is their market share that is most important. Get
>the patients money.
>ken


"Bristol-Myers is sponsoring its own clinical trial comparing 40
milligrams of Pravachol with 80 milligrams of Lipitor in an attempt to
prove that standard amounts of LDL reduction could be sufficient to
prevent major heart problems. "


http://story.news.yahoo.com/news?tmpl=story&cid=578&e=9&u=/nm/20031112/ts_nm/health_heart_pfizer_dc
 
On Wed, 12 Nov 2003 18:52:39 GMT, Jim Chinnis <[email protected]>
wrote:

> "Patrick Blanchard, M.D." <[email protected]> wrote in part:
>
>> On 12 Nov 2003 08:16:50 -0800, Brad Sheppard <[email protected]>
>> wrote:
>>
>>> Lipitor stops progression of plaque buildup. Don't let this newsgroup
>>> scare you from taking statins. "Patients taking Pfizer Inc's
>>> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
>>> experienced a significant reduction in the progression of
>>> atherosclerosis, or hardening of the arteries, compared to patients
>>> who received Pravachol (pravastatin), according to new data presented
>>> today at the annual meeting of the American Heart Association."
>>> http://www.pfizer.com/are/news_releases/mn_2003_1112.html
>>>
>>
>> I agree that statins should be considered in an overall treatment
>> against atherosclerosis
>>
>> http://tinyurl.com/uq5f
>>
>> Curr Med Res Opin. 2003;19(6):540-56. Early vascular benefits of statin
>> therapy.
>> Tsiara S, Elisaf M, Mikhailidis DP.
>> Internal Medicine Department, University of Ioannina Medical School,
>> Ioannina, Greece.
>>
>> ...A significant reduction of the carotid intima media thickness (IMT)
>> was also reported early after statin treatment...
>
> Anyone have the full text and know which statins were used in the study?
> --
> Jim Chinnis Warrenton, Virginia, USA
>

check you email and let me know if you didn't get it.

--
~~~
Patrick Blanchard, M.D., A.B.F.P.
Board Certified in Family Practice
http://www.familydoctor.org/blanchard
 
Jim Chinnis wrote:

> "Patrick Blanchard, M.D." <[email protected]> wrote in part:
>
> >On 12 Nov 2003 08:16:50 -0800, Brad Sheppard <[email protected]>
> >wrote:
> >
> >> Lipitor stops progression of plaque buildup. Don't let this newsgroup
> >> scare you from taking statins. "Patients taking Pfizer Inc's
> >> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
> >> experienced a significant reduction in the progression of
> >> atherosclerosis, or hardening of the arteries, compared to patients
> >> who received Pravachol (pravastatin), according to new data presented
> >> today at the annual meeting of the American Heart Association."
> >> http://www.pfizer.com/are/news_releases/mn_2003_1112.html
> >>
> >
> >I agree that statins should be considered in an overall treatment against
> >atherosclerosis
> >
> >http://tinyurl.com/uq5f
> >
> >Curr Med Res Opin. 2003;19(6):540-56. Early vascular benefits of statin
> >therapy.
> >Tsiara S, Elisaf M, Mikhailidis DP.
> >Internal Medicine Department, University of Ioannina Medical School,
> >Ioannina, Greece.
> >
> >...A significant reduction of the carotid intima media thickness (IMT) was
> >also reported early after statin treatment...
>
> Anyone have the full text and know which statins were used in the study?
> --
> Jim Chinnis Warrenton, Virginia, USA

The cited reference is a review of the literature, Jim.

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/
 
[email protected] (Brad Sheppard) wrote in message news:<[email protected]>...
> Lipitor stops progression of plaque buildup. Don't let this newsgroup
> scare you from taking statins. "Patients taking Pfizer Inc's
> cholesterol-lowering medicine Lipitor (atorvastatin calcium)
> experienced a significant reduction in the progression of
> atherosclerosis, or hardening of the arteries, compared to patients
> who received Pravachol (pravastatin), according to new data presented
> today at the annual meeting of the American Heart Association."
> http://www.pfizer.com/are/news_releases/mn_2003_1112.html



$tatin$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$4

www.pfizer.com???????????

Hardly an unbiased place to do your shopping Brad. Do you buy hardware
for your business the same way? Log onto Dell and take their word for
what their goods do and don't do?

Of course Lipitor will ream out your arteries Brad. It'll ream out
your brains too.

Care to, dare to, contact www.pfizer.com and the American Heart
Association (who are up to their clogged little arteries in funding
from Pfizer) for declared interests?

The good doctors have sold their names and the Heart Association has
sold its dignity and credibility down the river.

This is a pimped study Brad.

MFG
 
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