General fitness, health and nutrition · Public discussion

Statins

Started by J And B 50 · · Last activity · 5 posts · 399 views

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General fitness, health and nutrition
Published
24 March 2004
Last activity
25 March 2004
Original author
J And B 50
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5
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  1. I use Zocor also. Is there a reason one statin is prescribed
    over another?

  2. some physicians base their choice by literally interpreting
    studies done with specific statin drugs -- in other words,
    instead of inferring that there is a "class effect", they
    prescribe the specific drugs that were used in clinical
    trials and were shown to reduce the risk of stroke and heart
    attack (simvastatin is one of these).

    other physicians base their choice strictly upon the
    marketing recommendations of pharmaceutical
    representatives -- they get used to prescribing a specific
    statin and stick with it.

    other physicians base their choice upon the specific degree
    of lipid lowering needed in a patient -- since there are
    differences in potency among the statins, a physician might
    choose a different statin to treat someone with mild
    hyperlipidemia versus someone with more severe
    hyperlipidemia.

    most physicians will base their prescribing decision upon
    the specific drug / prescription plan that a patient carries
    -- they will prescribe the statin that is on the patient's
    approved drug formulary.

    "J and b 50" <[email hidden]> wrote in message news:20040324120725.03590.00000034@mb-
    m01.aol.com...

    Quoted message said:

    I use Zocor also. Is there a reason one statin is
    prescribed over another?

  3. Good information, thank you.

    jim b.

  4. (J and b 50) said:

    I use Zocor also. Is there a reason one statin is
    prescribed over another?

    1) Potency (some statins lower lipids more than others)
    2) Drug-drug interactions (some are metabolized by different
    pathways in the liver than others)
    3) Cost (restricted formularies, etc.)
    4) Specific clinical trials
    5) Physician comfort/familiarity (possibly influenced by
    drug reps)
    6) Patient preference ("My Dad's on Lipitor, so I'd like to
    use that.", or "I saw an ad for Zocor on TV..."😉

  5. (J and b 50) said:

    I use Zocor also. Is there a reason one statin is
    prescribed over another?

    My doctor researched drug interactions with my other meds
    before prescribing Lipitor. That's his primary criteria for
    choosing one med over another.

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