Thalidomide for multiple myeloma



A

Anth

Guest
Hi
Is anyone aware of if there's any evidence that Thalidomide actually extends
the life of a person with multiple myeloma?
The reason I'm asking is because there was a programme on TV about this new
'wonder drug'
I did a quick google and I couldn't find any randomised double blind trials
with extension of life in mind.
Thanks
Anth
http://www.eurekalert.org/pub_releases/2003-01/mc-ttf011003.php
 
"Anth" <[email protected]> wrote:

>Hi Is anyone aware of if there's any evidence that Thalidomide actually extends the life of a
>person with multiple myeloma?

It's showing promise in clinical trials.

>The reason I'm asking is because there was a programme on TV about this new 'wonder drug' I did a
>quick google and I couldn't find any randomised double blind trials with extension of life in mind.

Use this search string:

thalidomide "multiple myeloma" "clinical trials"

Tsu Dho Nimh

--
When businesses invoke the "protection of consumers," it's a lot like politicians invoking morality
and children - grab your wallet and/or your kid and run for your life.
 
"Anth" <[email protected]> wrote:

>Hi Is anyone aware of if there's any evidence that Thalidomide actually extends the life of a
>person with multiple myeloma? The reason I'm asking is because there was a programme on TV about
>this new 'wonder drug' I did a quick google and I couldn't find any randomised double blind trials
>with extension of life in mind. Thanks Anth http://www.eurekalert.org/pub_releases/2003-01/mc-
>ttf011003.php
>

It's early days yet. There is some information at
http://www.myeloma.org/myeloma/article.jsp?type=detail&articleId=90 and you can do a search at
http://www.myeloma.org/myeloma/home.jsp for more.

--
Peter Bowditch
The Millenium Project http://www.ratbags.com/rsoles
The Green Light http://www.ratbags.com/greenlight
and The New Improved Quintessence of the Loon with added Vitamins and C-Q10 http://www.ratbags.com/loon
To email me use my first name only at ratbags.com
 
I googled 'myeloma thalidomide phase III randomised'

As I thought, it looks promising but I couldn't find any 'golden standard' studies confirming
definite extension of life. (The T.V. programme showed the drug in a highly positive light, kind of
unfair as it may give sufferers false hope with respect to increased survival, but then again alt
med is unfair in that respect).

It is clear that the substance and its analogues offer other benefits, such as more options for drug
resistant myeloma as well as possible extension of life and reduced side effects associated with
some current cancer treatments.

The programme quoted that they have been experimenting with the original thalidomide molecule,
changing atoms here and there, thus minimising the side effects and risks associated with the
original molecule and enhancing the anti-cancer effects by thousands of times. One analogue showed
no teratogenic effects, whereas the original thalidomide did. So it should be possible to give to
pregnant women.

Time will tell if it extends life or not. Hopefully is will be useful in other cancers also. Anth

"Tsu Dho Nimh" <[email protected]> wrote in message
news:[email protected]...
> "Anth" <[email protected]> wrote:
>
[snips]

> Use this search string:
>
> thalidomide "multiple myeloma" "clinical trials"

> Tsu Dho Nimh
> --
> When businesses invoke the "protection of consumers," it's a lot like politicians invoking
> morality and children - grab your wallet and/or your kid and run for your life.
 
Thanks for info. Anth

"Peter Bowditch" <[email protected]> wrote in message
news:[email protected]...
> "Anth" <[email protected]> wrote:
>
> >Hi Is anyone aware of if there's any evidence that Thalidomide actually
extends
> >the life of a person with multiple myeloma? The reason I'm asking is because there was a
> >programme on TV about this
new
> >'wonder drug' I did a quick google and I couldn't find any randomised double blind
trials
> >with extension of life in mind. Thanks Anth http://www.eurekalert.org/pub_releases/2003-01/mc-
> >ttf011003.php
> >
>
> It's early days yet. There is some information at
> http://www.myeloma.org/myeloma/article.jsp?type=detail&articleId=90 and you can do a search at
> http://www.myeloma.org/myeloma/home.jsp for more.
>
> --
> Peter Bowditch The Millenium Project http://www.ratbags.com/rsoles The Green Light
> http://www.ratbags.com/greenlight and The New Improved Quintessence of the Loon with added
> Vitamins and
C-Q10 http://www.ratbags.com/loon
> To email me use my first name only at ratbags.com
 
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