Hi Is anyone aware of if there's any evidence that Thalidomide actually extends the life of a person with multiple myeloma? The reason I'm asking is because there was a programme on TV about this new 'wonder drug' I did a quick google and I couldn't find any randomised double blind trials with extension of life in mind. Thanks Anth http://www.eurekalert.org/pub_releases/2003-01/mc-ttf011003.php
Found this (with on control)- http://www.cancer.gov/clinicaltrials/results/thalidomide- comeback0500 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11435- 324&dopt=Abstract Anth
"Anth" <[email protected]> wrote: >Hi Is anyone aware of if there's any evidence that Thalidomide actually extends the life of a >person with multiple myeloma? It's showing promise in clinical trials. >The reason I'm asking is because there was a programme on TV about this new 'wonder drug' I did a >quick google and I couldn't find any randomised double blind trials with extension of life in mind. Use this search string: thalidomide "multiple myeloma" "clinical trials" Tsu Dho Nimh -- When businesses invoke the "protection of consumers," it's a lot like politicians invoking morality and children - grab your wallet and/or your kid and run for your life.
"Anth" <[email protected]> wrote: >Hi Is anyone aware of if there's any evidence that Thalidomide actually extends the life of a >person with multiple myeloma? The reason I'm asking is because there was a programme on TV about >this new 'wonder drug' I did a quick google and I couldn't find any randomised double blind trials >with extension of life in mind. Thanks Anth http://www.eurekalert.org/pub_releases/2003-01/mc- >ttf011003.php > It's early days yet. There is some information at http://www.myeloma.org/myeloma/article.jsp?type=detail&articleId=90 and you can do a search at http://www.myeloma.org/myeloma/home.jsp for more. -- Peter Bowditch The Millenium Project http://www.ratbags.com/rsoles The Green Light http://www.ratbags.com/greenlight and The New Improved Quintessence of the Loon with added Vitamins and C-Q10 http://www.ratbags.com/loon To email me use my first name only at ratbags.com
I googled 'myeloma thalidomide phase III randomised' As I thought, it looks promising but I couldn't find any 'golden standard' studies confirming definite extension of life. (The T.V. programme showed the drug in a highly positive light, kind of unfair as it may give sufferers false hope with respect to increased survival, but then again alt med is unfair in that respect). It is clear that the substance and its analogues offer other benefits, such as more options for drug resistant myeloma as well as possible extension of life and reduced side effects associated with some current cancer treatments. The programme quoted that they have been experimenting with the original thalidomide molecule, changing atoms here and there, thus minimising the side effects and risks associated with the original molecule and enhancing the anti-cancer effects by thousands of times. One analogue showed no teratogenic effects, whereas the original thalidomide did. So it should be possible to give to pregnant women. Time will tell if it extends life or not. Hopefully is will be useful in other cancers also. Anth "Tsu Dho Nimh" <[email protected]> wrote in message news:[email protected]... > "Anth" <[email protected]> wrote: > [snips] > Use this search string: > > thalidomide "multiple myeloma" "clinical trials" > Tsu Dho Nimh > -- > When businesses invoke the "protection of consumers," it's a lot like politicians invoking > morality and children - grab your wallet and/or your kid and run for your life.
Thanks for info. Anth "Peter Bowditch" <[email protected]> wrote in message news:[email protected]... > "Anth" <[email protected]> wrote: > > >Hi Is anyone aware of if there's any evidence that Thalidomide actually extends > >the life of a person with multiple myeloma? The reason I'm asking is because there was a > >programme on TV about this new > >'wonder drug' I did a quick google and I couldn't find any randomised double blind trials > >with extension of life in mind. Thanks Anth http://www.eurekalert.org/pub_releases/2003-01/mc- > >ttf011003.php > > > > It's early days yet. There is some information at > http://www.myeloma.org/myeloma/article.jsp?type=detail&articleId=90 and you can do a search at > http://www.myeloma.org/myeloma/home.jsp for more. > > -- > Peter Bowditch The Millenium Project http://www.ratbags.com/rsoles The Green Light > http://www.ratbags.com/greenlight and The New Improved Quintessence of the Loon with added > Vitamins and C-Q10 http://www.ratbags.com/loon > To email me use my first name only at ratbags.com
