Do you mean in terms of ride quality and grip? I haven't tried Tufos before. (The closest I've gotten is altering my Tufo cap to say "Tofu" instead. In my copious spare time, I would like to make a T-shirt that nearly nobody gets: Tofu, Meatless Bicycle Power.)
I guess it might help to know why Lance1965 is going for narrower tires. I was assuming more speed...