General fitness, health and nutrition · Public discussion

UV light may help RNA

Started by Tomhendricks474 · · Last activity · 1 post · 456 views

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General fitness, health and nutrition
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20 March 2004
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Tomhendricks474
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  1. Here's some support for my idea that UV may have been a key
    in prebiotic chemical selection - and it may have helped in
    RNA polymerization

    newscientist.comnews.jsp

    Excerpt:

    The World's No.1 Science & Technology News Service  UV light
    may have sparked life on Earth
    18:18 28 May 03   NewScientist.com news service   Ultra-
    violet light, long thought to be an impediment to the
    early formation of long organic molecules, may in fact
    hold the key to the origin of life, according to a new
    study. Intense UV rays from a young Sun bombarded the
    early Earth and were thought likely to destroy any
    exposed organic molecules. But a new mathematical model
    implies the radiation actually helped select out the
    molecular seeds of life.

    (snipped)

    Peculiar properties

    Life on Earth is thought to have evolved about 3.7 billion
    years ago, when there was no protective ozone layer encasing
    the planet and UV radiation was 100 times more intense than
    today. The nucleotides that make up RNA have three
    components - a sugar, a phosphate and nitrogen-containing
    base. "And these bases have very peculiar properties of
    being extremely efficient at quenching UV light," says
    Mulkidjanian, protecting the sugar and phosphate components
    which form the spine of the chain. The team fed data on the
    photochemistry of various organic molecules into a computer
    model designed to simulate the effects of UV light on
    stability. "The effect was very pronounced in RNA," he says.
    In the presence of strong UV light, RNA was much more likely
    to form long chains than other molecules.

    Also there is this old idea: the high point of absorbency on
    the spectrum is 260 nm - and IF that is a key to life and IF
    there is other life out there - then perhaps they will be
    signaling to us at the universal 260nm -

    A and U = 260nm, C = 275 nm, G 255 nm. Note that with these
    differences there may have been chemical prebiotic selection
    between the WC pairs.

    Tom

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