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Physiol Res. 2004;53(1):1-10. Related Articles, Links
UV Rays, the prooxidant/antioxidant imbalance in the cornea and oxidative eye damage.
Cejkova J, Stipek S, Crkovska J, Ardan T, Platenik J, Cejka C, Midelfart A.
Department of Eye Histochemistry and Pharmacology, Institute of Experimental Medicine, Academy of
Sciences of the Czech Republic, Videnska 1083, 14220, Prague 4, Czech Republic, e-mail:
[email protected]
In this minireview, the factors involved in the development of corneal injury due to an increased
amount of UVB rays are summarized. Experimental studies have shown that an increased number of UVB
rays leads to a profound decrease in corneal antioxidants (high molecular weight, antioxidant
enzymes as well as low molecular weight, mainly ascorbic acid) so that a prooxidant/antioxidant
imbalance appears. The decrease of corneal antioxidant protective mechanisms results in oxidative
injury of the cornea and causes damage of the inner parts of the eye by UVB rays and by reactive
oxygen species generated by them.
PMID: 14984308 [PubMed - in process]
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UV Rays, the prooxidant/antioxidant imbalance in the cornea and oxidative eye damage.
Cejkova J, Stipek S, Crkovska J, Ardan T, Platenik J, Cejka C, Midelfart A.
Department of Eye Histochemistry and Pharmacology, Institute of Experimental Medicine, Academy of
Sciences of the Czech Republic, Videnska 1083, 14220, Prague 4, Czech Republic, e-mail:
[email protected]
In this minireview, the factors involved in the development of corneal injury due to an increased
amount of UVB rays are summarized. Experimental studies have shown that an increased number of UVB
rays leads to a profound decrease in corneal antioxidants (high molecular weight, antioxidant
enzymes as well as low molecular weight, mainly ascorbic acid) so that a prooxidant/antioxidant
imbalance appears. The decrease of corneal antioxidant protective mechanisms results in oxidative
injury of the cornea and causes damage of the inner parts of the eye by UVB rays and by reactive
oxygen species generated by them.
PMID: 14984308 [PubMed - in process]
--------------------------------------------------------------------------
------
Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking