They're fine. A little on the heavy side, but never any big problems from what I've heard.
I have a rear 24h Aerohead O/C, which is an interesting concept. It hasn't gone out of true in 2 years with light training (and, in the past month, heavy training). It may or may not be due to the O/C design, but most likely not. No dents/bent rim from holes in the road, though.
I cannot comment on their hubs or pre-built wheels, as I do not own either.