There is ONE disadvantage to some Cannondale bikes which may not be a factor in your consideration ...
That is, Cannondale is a firm which occasionally incorporates a cutting edge design which may be technologically superior, but which may be unserviceable (at your LBS) in the future due to lack of availability of parts (I believe the "law" only requires a manufacturer to support a product for seven years after it is produced) ...
The innovative HEADSHOK comes to mind as a casualty of component evolution.