Road Cycling · Public discussion

Eki and Rogers go for better medals

Started by L. Seer · · Last activity · 27 posts · 999 views

Thread navigation

Jump through the discussion

Go to the original post, the replies on this page, or the latest preserved contribution.

Thread details

What we know about this thread

Original section
Road Cycling
Published
23 October 2004
Last activity
26 October 2004
Original author
L. Seer
Posts
27
Discussion status
Public discussion
Total views
999
Views / 30 days
0
Topics

The navigation and discussion metadata provide context. Posts remain in their original chronological order.

Showing posts 1–20 of 27
Posts remain in their original chronological order.

Text size
  1. The Australians, Russians, IOC, UCI, WADA, Rogers and Ekimov seem to
    all believe the test is reliable and that Tyler is not being truthful
    (read: they think he "is a doper and a lier"😉.

    I imagine that these groups have reviewed the test thoroughly before
    moving forward (perhaps this is why everything has moved to slowly
    since the Olympics). I have to believe that if the Australians and
    Russians found the test to be flawed, they would have joined Tyler in
    refuting the test in order to protect their own athletes from
    potential false positives in the future.

    Has the USOC voiced any opinion on the test or Tyler?

  2. "Tom Kunich" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    The Australians, Russians, IOC, UCI, WADA, Rogers and Ekimov seem to
    all believe the test is reliable and that Tyler is not being truthful
    (read: they think he "is a doper and a lier"😉.

    I imagine that these groups have reviewed the test thoroughly before
    moving forward (perhaps this is why everything has moved to slowly
    since the Olympics). I have to believe that if the Australians and
    Russians found the test to be flawed, they would have joined Tyler in
    refuting the test in order to protect their own athletes from
    potential false positives in the future.

    Has the USOC voiced any opinion on the test or Tyler?

    Tyler did make a rather good point - why, in ALL of the doping tests at
    the Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

    The test he had was one that identified DNA, other than his own, in his
    system. If others had doped with their own cells, then they would not be
    picked up by a DNA test. Another option is that he was the only cheat.
    Difficult to believe, but he was the only one caught. He has only kept his
    medal on a technicality. (The frozen second sample) but they are currently
    overturning technicality - the track lady who was pinged for 2 years even
    though she hadn't tested positive. Their were communications and records
    about her intent, but she didn't test positive. Tyler H did.

  3. "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    The Australians, Russians, IOC, UCI, WADA, Rogers and Ekimov seem to
    all believe the test is reliable and that Tyler is not being truthful
    (read: they think he "is a doper and a lier"😉.

    I imagine that these groups have reviewed the test thoroughly before
    moving forward (perhaps this is why everything has moved to slowly
    since the Olympics). I have to believe that if the Australians and
    Russians found the test to be flawed, they would have joined Tyler in
    refuting the test in order to protect their own athletes from
    potential false positives in the future.

    Has the USOC voiced any opinion on the test or Tyler?

    Tyler did make a rather good point - why, in ALL of the doping tests at the
    Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

  4. "Tom Kunich" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    The Australians, Russians, IOC, UCI, WADA, Rogers and Ekimov seem to
    all believe the test is reliable and that Tyler is not being truthful
    (read: they think he "is a doper and a lier"😉.

    I imagine that these groups have reviewed the test thoroughly before
    moving forward (perhaps this is why everything has moved to slowly
    since the Olympics). I have to believe that if the Australians and
    Russians found the test to be flawed, they would have joined Tyler in
    refuting the test in order to protect their own athletes from
    potential false positives in the future.

    Has the USOC voiced any opinion on the test or Tyler?

    Tyler did make a rather good point - why, in ALL of the doping tests at
    the Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

    I think that I am missing your point. Is your point that if Tyler was blood
    doping then there must have been a bunch of other cyclists blood doping, and
    why were they not caught?

  5. malcolmkmay said:

    "Tom Kunich" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    The Australians, Russians, IOC, UCI, WADA, Rogers and Ekimov seem to
    all believe the test is reliable and that Tyler is not being truthful
    (read: they think he "is a doper and a lier"😉.

    I imagine that these groups have reviewed the test thoroughly before
    moving forward (perhaps this is why everything has moved to slowly
    since the Olympics). I have to believe that if the Australians and
    Russians found the test to be flawed, they would have joined Tyler in
    refuting the test in order to protect their own athletes from
    potential false positives in the future.

    Has the USOC voiced any opinion on the test or Tyler?

    Tyler did make a rather good point - why, in ALL of the doping tests at
    the Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

    The test he had was one that identified DNA, other than his own, in his
    system. If others had doped with their own cells, then they would not be
    picked up by a DNA test. Another option is that he was the only cheat.
    Difficult to believe, but he was the only one caught. He has only kept his
    medal on a technicality. (The frozen second sample) but they are currently
    overturning technicality - the track lady who was pinged for 2 years even
    though she hadn't tested positive. Their were communications and records
    about her intent, but she didn't test positive. Tyler H did.

    No, the test was not looking for foreign DNA. It was looking for the presence of unexpected foreign antigens and expected antigens present in lower percentages than expected.

    No DNA tests were performed.

  6. Tom Kunich said:

    "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    The Australians, Russians, IOC, UCI, WADA, Rogers and Ekimov seem to
    all believe the test is reliable and that Tyler is not being truthful
    (read: they think he "is a doper and a lier"😉.

    I imagine that these groups have reviewed the test thoroughly before
    moving forward (perhaps this is why everything has moved to slowly
    since the Olympics). I have to believe that if the Australians and
    Russians found the test to be flawed, they would have joined Tyler in
    refuting the test in order to protect their own athletes from
    potential false positives in the future.

    Has the USOC voiced any opinion on the test or Tyler?

    Tyler did make a rather good point - why, in ALL of the doping tests at the
    Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

    350 Athletes were given this test at Athen. That a small fraction of the athletes at the Olympics.

  7. "Tom Kunich" <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    The Australians, Russians, IOC, UCI, WADA, Rogers and Ekimov seem to
    all believe the test is reliable and that Tyler is not being truthful
    (read: they think he "is a doper and a lier"😉.

    I imagine that these groups have reviewed the test thoroughly before
    moving forward (perhaps this is why everything has moved to slowly
    since the Olympics). I have to believe that if the Australians and
    Russians found the test to be flawed, they would have joined Tyler in
    refuting the test in order to protect their own athletes from
    potential false positives in the future.

    Has the USOC voiced any opinion on the test or Tyler?

    Tyler did make a rather good point - why, in ALL of the doping tests at the
    Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

    Could he have been the only one tested who actually had a homologous
    transfusion? I've seen a number as low as 297 Olympic athletes (not
    necessarily medal winners) who had this blood-test performed on
    them...and that's from all sports and a pool of 10,000 athletes.

    Also, remember that auto-transfusions are not detectable, and if you
    were someone who does auto-transfusions, it cannot be done repeatedly
    (maybe twice??) within a year due to the need to rebuild your blood
    between donations, which can hurt your training and kill performance.
    So, it appears that auto-transfusions are most effective for someone
    who really only needs to perform at the top for one stretch during the
    year, and then can take a big break to give more blood for the next
    season without risking performance or important training.

    H-transfusions provided a lot more flexibility...well, up to this
    year's Olympics it appears.

  8. (L. Seer) said:

    Could he have been the only one tested who actually had a homologous
    transfusion? I've seen a number as low as 297 Olympic athletes (not
    necessarily medal winners) who had this blood-test performed on
    them...and that's from all sports and a pool of 10,000 athletes.

    And TH was the only positive? Weird.

    Quoted message said:

    Also, remember that auto-transfusions are not detectable,

    incorrect. Neocyte count, hct.

    Quoted message said:

    and if you
    were someone who does auto-transfusions, it cannot be done repeatedly
    (maybe twice??)

    Leapfrogging allows many times per year. In Auto transfusions for elective
    sgy, the pt can start like 5 weeks out and get 2-3 units by sgy. And these
    are older, but reasonable health pts. The blood doesn't even need to be
    frozen. It's a give...come back, get back 1 and draw 2, come back in week
    before sgy, if hct is above 38, give another. That's three in 6 weeks.

    Two of these in this scenario can be frozen and rejuvenated (more 2,3 DPG
    Added!) Allowing support of 2 units on call at any time. We had pts with
    rare blood type/rare antibody who had a bank of like 8-10 units in 6 months
    and were always walking around with nearly normal Hct. Yada, yada.

    They don't want system stress on pts getting sgy. For TH, there'd be rapid
    replacement of first unit, Hct near normal amt in a few days. The rest are
    leap-frog, so even less stress, since you get one back while in the chair.
    These kinds would -not- cause net neocyte increase, b/c there's no
    deficit...blah, blah. In some ppl there can be some complications, for
    instance just giving blood like at a blood drive can cause temporary drop
    in immune system in some.

    Quoted message said:

    within a year due to the need to rebuild your blood
    between donations, which can hurt your training and kill performance.

    Quoted message said:

    So, it appears that auto-transfusions are most effective for someone
    who really only needs to perform at the top for one stretch during the
    year, and then can take a big break to give more blood for the next
    season without risking performance or important training.

    You have not lassoed the correct with these ideas, my friend. There are
    even more subtle and restrained techniques. One is that instead of drawing
    out a full unit a pediatric unit, or even a 60cc syringe, and these can be
    combined and washed with saline and stored, rejuvenated, etc.

    These have been developed b/c of the vast array of special cases, pediatric
    pts, and things like JWitnesses, etc.

    HTH,

    -B

  9. "malcolmkmay" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:


    The test he had was one that identified DNA, other than his own, in his
    system.

    Sorry but it does no such thing. It identifies minor blood groupings. Most
    people only have a single minor type so signs of multiple groupings are
    assumed to be proof of blood packing. However, there are some people who
    have more than a single minor blood type.

    Whether or not this was Tyler's problem or as was noted in the Letters to
    the Editor in Cycling News (forget the week) the tests were never properly
    tested with controls so that it isn't clear what the percentage of false
    positives are. We do know that there was at least one false negative and
    possibly two in a fairly small test.

    If this was a DNA test there'd have been no questions other than the clear
    professionalism used to perform the test. But that was NOT the case.

  10. "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    "Tom Kunich" <[email hidden]> wrote in message
    news:<[email hidden]>...

    Quoted message said:


    Tyler did make a rather good point - why, in ALL of the doping tests at
    the
    Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

    Could he have been the only one tested who actually had a homologous
    transfusion? I've seen a number as low as 297 Olympic athletes (not
    necessarily medal winners) who had this blood-test performed on
    them...and that's from all sports and a pool of 10,000 athletes.

    I had heard that there was 100% testing at this Olympics. Perhaps I was
    wrong. Nevertheless, it is noteworthy that they didn't release the
    hematocrit as well as the claim of blood packing.

    Quoted message said:

    Also, remember that auto-transfusions are not detectable, and if you
    were someone who does auto-transfusions, it cannot be done repeatedly
    (maybe twice??) within a year due to the need to rebuild your blood
    between donations, which can hurt your training and kill performance.

    Hmm, exactly when do you suppose a professional racer could have the time to
    donate a pint of blood? And then why would he save it for the Olympics
    rather than the Tour or the World Championships? The idea that athletes can
    perform autologous transfusions is pretty naive. How do you store the stuff?
    Since it has a life in the refrigerator of only a couple of months on the
    outside this is a really impractical idea.

  11. Tom Kunich said:

    Hmm, exactly when do you suppose a professional racer could have the time to
    donate a pint of blood? And then why would he save it for the Olympics
    rather than the Tour or the World Championships? The idea that athletes can
    perform autologous transfusions is pretty naive. How do you store the stuff?
    Since it has a life in the refrigerator of only a couple of months on the
    outside this is a really impractical idea.

    Tom, your comment makes sense, and I agree, mostly. I posted a little about
    autologous blood storage in this thread.

    I know -nothing- about the pro cyclist blood doping scene, not even one
    scrap.

    I can tell you that using procedures designed for pediatric patients, an
    adult cyclist could possibly store 2 adult units in under 60 min total time
    in the donor room over 6 weeks, or less, but would require careful advanced
    Transfusion Medicine techniques. He would have no discernable reduction in
    Hct, or performance, unless he raced 5 minutes after the first donation!
    <g> Then he might feel light-headed, but probably no effect for 80% of
    people. (still we wouldn't advise this, being in risk mgmt).

    I could also see agreeing with you depending on circumstances - it's not
    exactly something that a pro biker could do casually.

    Could a pro biker (>110lbs) _theoretically_ store his own blood prior to
    the season, at (picking a number) 6-8 units autologus blood, a unit needed
    for six occasions throughout the upcoming season, given 8 weeks of prep,
    storage? (or if EPO given at this phase, much less, dep on pre-donation
    hct)

    A qualified 'yes'.

    Here the blood would be stored frozen, deglyced, rejuvenated, washed. Turn
    around time, 2 units per hr, ready to transfuse first unit in 30 min, take
    15 min to retransfuse first unit, and then as needed each additional unit
    as fast as tolerated after first 5 minutes, ~20 min per unit...total
    retransfusion time for 6 units, 180 min. Total time in the donor room for 6
    units - as little as 60 minutes given good veins, for grand total of about
    4 hours cumulative time over a 6 month season, <30 min on any one week of
    the event, say six events.

    Things like three pedi-units (110ml packed cells x3) stored on 100lb kids,
    not too hard in a couple months. Freezing, or even targetted storage at
    2-4deg C, not imossible.

    Maybe google on transfusion, autologous, leap frog (-ging).?

    Again, I'm not disagreeing with you actually I agree.

    o Hard to do casually.
    o Very easy to do if dedicated, intense and directed program with expert
    administration.

    HTH.

    -B
    Addendum:
    Adult: single unit blood - ~425 ml whole blood. ~180-200 ml packed cells.
    Pediatric: single unit ~220 ml WB ~90ml packed cells.

  12. Badger South said:


    snip
    I know -nothing- about the pro cyclist blood doping scene, not even one scrap.
    snip


    Sports physicians do believe that there is a noticeable drop in performance for elite athletes if they donate blood. Thus, most blood doping elite athletes would prefer to use homologous rather than autologous blood.

    As stated above, blood does not store particularly well so it wouldn't be very effective to donate prior to the season for autologous use.

    Also, if an athlete did use autologous blood, their haematocrit level would be unlikely to lead to a positive result for a high Hct. Either they would keep it under the legal level or else they would haemodilute with lots of fluids (IV or oral) prior to the test.

  13. patch70 said:


    Badger South said:


    snip
    I know -nothing- about the pro cyclist blood doping scene, not even one
    scrap.
    snip


    Sports physicians do believe that there is a noticeable drop in
    performance for elite athletes if they donate blood. Thus, most blood
    doping elite athletes would prefer to use homologous rather than
    autologous blood.

    Quibble. You're talking (and they) about an elite athlete becoming a Red
    Cross Frquent flier, donating blood as a community service. Other regimes
    exist...and for self-storage, more subtle schedules could easily be used
    (pedi-units).

    You sound like you know the scene, so no argument, just informing from my
    experiences in a hospital.

    Do the pros possible (or do you know) do things like have a private
    mini-blood bank going on with a small core of donors who are well-known,
    etc.? Blood administration and blood banks are highly regulated, and you
    couldn't walk into one, even if yo knew the director, and said 'give me 5
    units of type xyz blood, here's 450 bucks', <g> I have a hard time
    imagining some 'under the table' blood-to-athletes program, iow.

    Most long term donors in Bloodbanks are very, very safe. It's the
    first-time donors for which you have no history of transfusion, life style,
    etc. that turn up the TDT positives.

    Quoted message said:

    As stated above, blood does not store particularly well so it wouldn't
    be very effective to donate prior to the season for autologous use.

    We had a well-established and sophisticated autologous donation program
    that I helped administrate way back in the 1980s. It involved frozen blood,
    though. Storing autol. blood 'on the shelf' at 2-4 deg C 35 to 42 days with
    the new anticoaglulants (Adsol) would only lead to one or two units being
    available for the season - unless you used a frozen auto blood regime!

    Some advanced Anticoagulants were reported to store well to 56 days, but
    not approved yet. Got good 75% recovery of chromium survival studies with
    the new stuff, though. Ultimately they stuck with 42 days with adsol..

    Quoted message said:

    Also, if an athlete did use autologous blood, their haematocrit level
    would be unlikely to lead to a positive result for a high Hct. Either
    they would keep it under the legal level or else they would haemodilute
    with lots of fluids (IV or oral) prior to the test.

    Again, depends on the sophistication. But you're saying you know most pros
    use homologous, which is fine. Any thoughts on why TH was the only one (we
    know of) that was caught?

    -B

  14. patch70 said:


    Badger South said:


    snip
    I know -nothing- about the pro cyclist blood doping scene, not even one
    scrap.
    snip


    Sports physicians do believe that there is a noticeable drop in
    performance for elite athletes if they donate blood. Thus, most blood
    doping elite athletes would prefer to use homologous rather than
    autologous blood.

    As stated above, blood does not store particularly well so it wouldn't
    be very effective to donate prior to the season for autologous use.

    Also, if an athlete did use autologous blood, their haematocrit level
    would be unlikely to lead to a positive result for a high Hct. Either
    they would keep it under the legal level or else they would haemodilute
    with lots of fluids (IV or oral) prior to the test.

    One thing we might be missing...

    Though most donor programs only allow donation every 8 weeks, this does
    -not- necessarily mean they could not donate again in one week, or that
    this would harm a normal donor in any way (at 228lbs, I could easily give 2
    units of blood and in 3 days go out and ride my usual routes, and even show
    improvement typical of newbies...

    IOW, your red cells return to normo-static levels -very- quickly. You give
    200cc of packed cells from an 8-10 liter WB blood volume and it's really
    nothing...the body is replacing it from the spleen, and the bonemarrow is
    cranking almost immediately.

    Studies...are done with a goal in mind. Various quantities of blood
    donated, treadmills run...unless you're saying you -are- a sports
    physician, and have run such a controlled study, what they -believe- can
    be, um, anecdotal. "Oh, don't go donating blood before a race to get pizza
    and T-shirt at the Red Cross...it will make you run slower than molassas
    tomorrow" type of thing. Heh.

    Actually, -improvement- in an 'elite athlete' could be theorized as a
    result of donating a few hundred cc of blood. Decreased viscosity, improved
    turnover of older cells, iron load dimished...yadda. yadda.

    180cc of packed cells, or in a 'pediatric donation', 90ccs would not even
    be measurable, the the athlete might say 'whoa, I feel tired..it would be
    90% psychological'. Do this 3 times over a month, and you have a spare
    unit. Add 270cc of auto blood to an athlete the night before a race, and
    the hct might go up 1%. Give 450cc (5 mini units collected once per week
    available with 7 days left on exp. date), hct might go up 2%.

    The athlete would -not- notice 5 donations over 35 days of 90cc. The body
    may hypercompensate.... We sometimes draw 10cc tubes from sick pts, 4 of
    them every day for a week just to monitor blood in majorly sick ppl.

    Even among a group like those tiny elite cyclists, most of them weigh
    135lbs to 170lbs, (guess). Pediatric pts are typically 80lbs or less.

    So while blood is important to cyclists, and higher hct is important, and
    giving exogenous blood will boost the body, the flip side..._giving_
    90-180cc of packed blood will not cause an equal and noticeable 'decrease'
    in performance.

    IOW, you -get- 2 units of prbc, the hct goes up 1-2%, the TT time goes down
    30-45 seconds.

    You _donate_ 0.5 to 1 unit of blood, the hct stays the same, the TT time
    stays the same. Splitting hairs, hct might go from 45.5% to 45.4% with a
    couple hundred cc of prbc donated. TT time might go down 1/2 second or not
    at all by the following day. Picking times out of the air, but it's not a
    comparable sitch between giving and getting.

    You say it -is- homologous administration for state of the art in the
    cycling world, b/c you are an insider, run a lab, race director, MD, and
    -know- this, I say fine, no prob. Thanks.

    But -what- you gave as reasons? uh not so much with the true.

    If you are a fan and are conjecturing, then I'm saying I was a
    professional, though in the blood bank field, and not the -cycling- field
    per se, and -know- absolutely the factoids I'm giving you are not only
    true, I did them every day. I ran an apheresis service in addition, was
    certified, and licensed.

    No big deal, fun to discuss.

    -B

  15. "Tom Kunich" <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    "L. Seer" <[email hidden]> wrote in message
    news:[email hidden]...

    Quoted message said:

    "Tom Kunich" <[email hidden]> wrote in message
    news:<[email hidden]>...

    Quoted message said:


    Tyler did make a rather good point - why, in ALL of the doping tests at
    the
    Olympics and the World Championships was he the only one that tested
    positive for blood packing? I believe that there was 100% testing at the
    Olympics. If blood packing were occurring why is it that only Hamilton
    tested positive?

    Could he have been the only one tested who actually had a homologous
    transfusion? I've seen a number as low as 297 Olympic athletes (not
    necessarily medal winners) who had this blood-test performed on
    them...and that's from all sports and a pool of 10,000 athletes.

    I had heard that there was 100% testing at this Olympics. Perhaps I was
    wrong. Nevertheless, it is noteworthy that they didn't release the
    hematocrit as well as the claim of blood packing.

    Quoted message said:

    Also, remember that auto-transfusions are not detectable, and if you
    were someone who does auto-transfusions, it cannot be done repeatedly
    (maybe twice??) within a year due to the need to rebuild your blood
    between donations, which can hurt your training and kill performance.

    Hmm, exactly when do you suppose a professional racer could have the time to
    donate a pint of blood? And then why would he save it for the Olympics
    rather than the Tour or the World Championships? The idea that athletes can
    perform autologous transfusions is pretty naive. How do you store the stuff?
    Since it has a life in the refrigerator of only a couple of months on the
    outside this is a really impractical idea.

    this is a very rough description of the procedure:

    http://www.gen.umn.edu/faculty_staff/jensen/1135/example_student_projects/Sum2000/Blood_doping/dopehow.htm

    This procedure can be augmented by the use of drugs as well. When you
    do it depends on your business/performance agenda. If I was doing it
    to prepare for the Tour, I would do it with the help of EPO products
    (if needed) in May when I'm doing a series of "training camps" when a
    bit of rest before pushing my form for the Tour may be appropriate,
    or, I'm not needing to train much beyond low intensities for a couple
    weeks.

    I wonder what the folks at WADA, the UCI, and just about every
    endurance sport governing body would think about you calling them
    naive?

  16. L. Seer said:

    this is a very rough description of the procedure:

    http://www.gen.umn.edu/faculty_staff/jensen/1135/example_student_projects/Sum2000/Blood_doping/dopehow.htm

    This is cool:

    Quoted message said:

    Pre-Infusion Post-Infusion Difference %Difference
    Hemoglobin, g . 100 ml blood-1 13.8 17.6 3.8* +27.5*
    Hematocrit°, % 43.3 54.8 11.5* +26.5*
    Submaximal VO2 l . min-1 1.60 1.59 -0.01 -0.6
    Submaximal HR, b . min-1 127.4 109.2 18.2 -14.3*
    Max VO2, l . min-1 3.28 3.70 0.42* +12.8*
    Max HR, b . min-1 181.6 180.0 -1.6 -0.9
    Treadmill Run Time, sec 793 918 125* +15.8

    * Hematocrit is presented as the percent (%) of 100 ml of whole blood occupied by the red blood cells.
    * Difference is statistically significant.

    So for these 5 treadmill-running mountain climbers, they gained a
    percent increase V02 max for each 2 percent increase in hematocrit.

  17. Badger South <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:
    (L. Seer) said:

    Could he have been the only one tested who actually had a homologous
    transfusion? I've seen a number as low as 297 Olympic athletes (not
    necessarily medal winners) who had this blood-test performed on
    them...and that's from all sports and a pool of 10,000 athletes.

    And TH was the only positive? Weird.

    Apparently he was the only one, although we do not know if there are
    any other cases pending where the athlete did not chose to disclose
    the information to the public like Tyler.

    How is it weird? Is one in 297 an odd percentage somehow?

    Quoted message said:
    Quoted message said:

    Also, remember that auto-transfusions are not detectable,

    incorrect. Neocyte count, hct.

    Please explain how it can currently be detected. There has been talk
    of a hematological passport, but so far, hct/reticulocyte/hgb levels
    have only been used by the UCI (not Olympic games) to limit how much a
    rider can dope (if they can) but not to detect doping (hence vactions
    not sanctions). I assume that if it could be reliably detected, they
    would quickly implement methods of enforcement like they have
    h-transfusions. Perhaps the hematological passport with address total
    RBC population age in addition to hct/rtc %/hgb in the future and some
    kind of "normal" age range will be set, but up to now, a-transfusions
    are limited by hct and hgb where these levels are checked, but it is
    not detectable. Gees, even with RBC population age monitored, it is
    not inconvievable for a sophistocated and well-funded doper to adjust
    their cell population age to fit within "legal" parameters anyway.

    Quoted message said:
    Quoted message said:

    and if you
    were someone who does auto-transfusions, it cannot be done repeatedly
    (maybe twice??)

    Leapfrogging allows many times per year. In Auto transfusions for elective
    sgy, the pt can start like 5 weeks out and get 2-3 units by sgy. And these
    are older, but reasonable health pts. The blood doesn't even need to be
    frozen. It's a give...come back, get back 1 and draw 2, come back in week
    before sgy, if hct is above 38, give another. That's three in 6 weeks.

    Two of these in this scenario can be frozen and rejuvenated (more 2,3 DPG
    Added!) Allowing support of 2 units on call at any time. We had pts with
    rare blood type/rare antibody who had a bank of like 8-10 units in 6 months
    and were always walking around with nearly normal Hct. Yada, yada.

    They don't want system stress on pts getting sgy. For TH, there'd be rapid
    replacement of first unit, Hct near normal amt in a few days. The rest are
    leap-frog, so even less stress, since you get one back while in the chair.
    These kinds would -not- cause net neocyte increase, b/c there's no
    deficit...blah, blah. In some ppl there can be some complications, for
    instance just giving blood like at a blood drive can cause temporary drop
    in immune system in some.

    Quoted message said:

    within a year due to the need to rebuild your blood
    between donations, which can hurt your training and kill performance.

    Quoted message said:

    So, it appears that auto-transfusions are most effective for someone
    who really only needs to perform at the top for one stretch during the
    year, and then can take a big break to give more blood for the next
    season without risking performance or important training.

    You have not lassoed the correct with these ideas, my friend. There are
    even more subtle and restrained techniques. One is that instead of drawing
    out a full unit a pediatric unit, or even a 60cc syringe, and these can be
    combined and washed with saline and stored, rejuvenated, etc.

    These have been developed b/c of the vast array of special cases, pediatric
    pts, and things like JWitnesses, etc.

    HTH,

    -B

    There is more than one way to skin a cat!

  18. (L. Seer) said:
    Quoted message said:
    Quoted message said:

    Also, remember that auto-transfusions are not detectable,

    incorrect. Neocyte count, hct.

    Please explain how it can currently be detected. There has been talk
    of a hematological passport, but so far, hct/reticulocyte/hgb levels
    have only been used by the UCI (not Olympic games) to limit how much a
    rider can dope (if they can) but not to detect doping (hence vactions
    not sanctions). I assume that if it could be reliably detected, they
    would quickly implement methods of enforcement like they have

    OK, you are for practical purposes, correct. I'll stand corrected. My dumb
    head was thinking exhaustive testing, smear, history (passport)...

    Thanks for sticking with this, w/me. ;-)

    -B

  19. Badger South <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:


    Do the pros possible (or do you know) do things like have a private
    mini-blood bank going on with a small core of donors who are well-known,
    etc.?

    That's where we're having this misunderstanding. Doping by necessity
    is a motel room situation. There mustn't be any witnesses to later
    testify. Therefore blood packing isn't a case of using treated blood
    but a simple case of re-infusing the blood as removed from the
    athlete.

    Quoted message said:

    Blood administration and blood banks are highly regulated, and you
    couldn't walk into one, even if yo knew the director, and said 'give me 5
    units of type xyz blood, here's 450 bucks', <g> I have a hard time
    imagining some 'under the table' blood-to-athletes program, iow.

    Indeed and that is why it seems so outlandish to me that there is this
    large scale blood packing going on in ANY athletic sport.

  20. [email hidden] (L. Seer) wrote in message news:<[email hidden]>...

    Quoted message said:

    "Tom Kunich" <[email hidden]> wrote in message news:<[email hidden]>...

    Quoted message said:

    Since it has a life in the refrigerator of only a couple of months on the
    outside this is a really impractical idea.

    this is a very rough description of the procedure:

    http://www.gen.umn.edu/faculty_staff/jensen/1135/example_student_projects/Sum2000/Blood_doping/dopehow.htm

    That procedure notes that the blood is frozen. Freezing blood ruptures
    the cell walls and breaks the cells into fragments. Being given a
    single unit of frozen blood can be detected without any complicated
    test. Blood like this DOES increase the VO2 max for a couple of days
    until your body eliminates the fragmentary cells from your blood
    street, but I'm sure that it doesn't work as well as whole cells.

    To read this stuff you'd almost believe that this is a low tech method
    that you could do in your garage.

    Quoted message said:

    This procedure can be augmented by the use of drugs as well.

    But not indetectably.

Active in the last 60 minutes

Active in this thread

0 users · 0 guests ·0 bots ·0 total

No signed-in users are active right now.

No known search crawlers active right now.