General fitness, health and nutrition · Public discussion

Re: too much corn in diet may lead to pellagra, niacin deficiency

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General fitness, health and nutrition
Published
9 December 2004
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9 December 2004
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  1. Yes, indians of the american southwest use a lime solution for their corn
    meal to avoid this problem.

    Quoted message said:

    If I remember my biochemistry right, the reason pellagra occurs in groups
    who consume a lot of corn is that the corn is their major source of
    protein and corn is deficient in tryptophan. One of the more minor
    metabolic pathways for tryptophan leads to nicotinic acid (a form of
    niacin) and is capable of supplying about half the daily requirement of
    niacin (note that "vitamin" doesn't imply "can't be synthesized by the
    body at all" but merely "can't be synthesized by the body in adequate
    amounts"😉. People whose diet has corn as its major protein source
    generally don't consume many dietary sources of niacin as such. In
    short, they're malnourished. Increasing the amount of corn in the diet
    of a person who isn't malnourished will *not* cause a niacin deficiency.

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