General fitness, health and nutrition · Public discussion

Hold that shot - oral B12 works too

Started by Roman Bystrianyk · · Last activity · 4 posts · 292 views

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General fitness, health and nutrition
Published
25 May 2005
Last activity
27 May 2005
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Roman Bystrianyk
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  1. http://www.healthsentinel.com/news.php?event=news_print_list_item&id=859

    Alison McCook, "Hold that shot - oral B12 works too", Reuters, May 24,
    2005,
    Link:
    http://www.reuters.com/newsArticle.jhtml?type=healthNews&storyID=8590201

    Oral supplements of vitamin B12 appear to correct vitamin B12
    deficiencies as well as B12 injections, according to study findings
    released Monday.

    However, the group of European researchers found that, in order to
    correct a deficiency, oral doses need to contain more than 200 times
    the recommended daily allowance (RDA) of vitamin B12.

    Study author Dr. Lisette C. P. G. M. de Groot of Wageningen University
    in the Netherlands explained that most people develop vitamin B12
    deficiencies as a result of "malabsorption," in which their bodies
    become unable to extract vitamin B12 from food.

    The deficiency typically strikes older people, she added, and takes
    years to develop. In some instances, people who avoid animal products
    -- such as vegans and followers of a macrobiotic diet -- can also
    develop a deficiency in vitamin B12 as a result of not eating enough
    B12-rich foods, de Groot noted.

    A vitamin B12 deficiency is typically treated by monthly, often
    painful, shots, de Groot and her colleagues, including Simone J. P. M.
    Eussen, report in the Archives of Internal Medicine.

    To investigate whether an oral dose of vitamin B12 works, as well, they
    tested various daily doses of oral vitamin B12 supplements in 120
    people aged 70 and older.

    They found that daily oral doses of 647 to 1032 micrograms of vitamin
    B12 appeared to correct the deficiency. The current RDA for vitamin B12
    is 3 micrograms per day.

    Despite the massive doses needed, oral medicine has the advantage of
    being easy to administer and painless, de Groot told Reuters Health. No
    side effects have been reported, she added.

    SOURCE: Archives of Internal Medicine, May 23, 2005.

  2. This is the world's oldest news.

  3. Sbharrisatsignix.netcom.com said:

    This is the world's oldest news.

    SOURCE: Archives of Internal Medicine, May 23, 2005.

    The May 23, 2005 date makes it new, news. You being a research
    baffoon, ... eh, research MD you should know how the game works.

    Ha, ... Hah, Ha!

  4. No, truthfully, I usually expect more from the Annals of Internal
    Medicine. This has only been known for about 30 years. It's not
    entirely the newspapers' fault.

    J Am Geriatr Soc. 1998 Sep;46(9):1125-7.

    Oral cobalamin for pernicious anemia: back from the verge of
    extinction.

    Lederle FA.

    Department of Medicine, Minneapolis Veterans Affairs Medical Center, MN
    55417,
    USA.

    BACKGROUND: High dose oral cobalamin therapy was shown to be effective
    for
    pernicious anemia and other cobalamin deficiency states 30 years ago,
    and
    physicians and patients state that they would find oral therapy useful,
    but a
    survey conducted in 1989 found that physicians were generally unaware
    of it.
    OBJECTIVE: To assess physician awareness and use of oral cobalamin
    since 1989.
    DESIGN, SETTING, AND PARTICIPANTS: Minneapolis area internists not
    listed as
    having subspecialties or academic business addresses were surveyed in
    1989 and
    in 1996. MEASUREMENTS AND RESULTS: There were 245 responses to the 1989
    survey
    and 223 responses to the 1996 survey for response rates of 68% and 69%,
    respectively. The percentage of internists who ever used oral cobalamin
    to treat
    pernicious anemia increased from 0 in 1989 to 19% in 1996 (P < .001).
    The
    percentage who were aware of an effective oral cobalamin preparation
    for
    treating cobalamin deficiency states also increased significantly from
    4 to 29%
    (P < .001). The percentage of internists who agreed with the incorrect
    view that
    sufficient quantities of cobalamin cannot be absorbed when given orally
    declined
    from 91% in 1989 to 71% in 1996 (P < .001). CONCLUSION: Minneapolis
    internists'
    awareness and use of oral cobalamin treatment for pernicious anemia
    increased
    substantially between 1989 and 1996, but the majority of internists
    remained
    unaware of this treatment option.

    PMID: 9736106 [PubMed - indexed for MEDLINE]

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