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White Flour Contains Diabetes-Causing Contaminant Alloxan

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  1. Preventive Psychiatry E-Newsletter # 211

    White Flour Contains Diabetes-Causing Contaminant Alloxan

    http://www.newstarget.com/z008191.html

    Sunday, June 19, 2005

    You may want to think twice before eating your next sandwich on white
    bread. Studies show that alloxan, the chemical that makes white flour
    look "clean" and "beautiful," destroys the beta cells of the pancreas.
    That's right; you may be devastating your pancreas and putting yourself
    at risk for diabetes, all for the sake of eating "beautiful" flour. Is
    it worth it?

    Scientists have known of the alloxan-diabetes connection for years; in
    fact, researchers who are studying diabetes commonly use the chemical
    to induce the disorder in lab animals. In the research sense, giving
    alloxan to an animal is similar to injecting that animal with a deadly
    virus, as both alloxan and the virus are being used specifically to
    cause illness. Every day, consumers ingest foods made with
    alloxan-contaminated flour. Would they just as willingly consume foods
    tainted with a deadly virus? Unless they had a death wish, they
    probably would not. Unfortunately, most consumers are unaware of
    alloxan and its potentially fatal link to diabetes because these facts
    are not well publicized by the food industry.

    How does alloxan cause diabetes? According to Dr. Hari Sharma's Freedom
    from Disease, the uric acid derivative initiates free radical damage to
    DNA in the beta cells of the pancreas, causing the cells to malfunction
    and die. When these beta cells fail to operate normally, they no longer
    produce enough insulin, or in other words, they cause one variety of
    adult-onset type 2 diabetes. Alloxan's harmful effects on the pancreas
    are so severe that the Textbook of Natural Medicine calls the chemical
    "a potent beta-cell toxin." However, even though the toxic effect of
    alloxan is common scientific knowledge in the research community, the
    FDA still allows companies to use it when processing foods we ingest.

    The FDA and the white flour industry could counter-argue that, if
    alloxan were to cause diabetes, a higher proportion of Americans would
    be diabetic. After all, more consumers consume white flour on a regular
    basis than are actually diabetic. This point is valid, but it does not
    disprove the alloxan-diabetes connection. While alloxan is one cause of
    adult-onset type 2 diabetes, it is of course not the only cause. As the
    Textbook of Natural Medicine states, "current theory suggests an
    hereditary beta-cell predisposition to injury coupled with some defect
    in tissue regeneration capacity" may be a key cause. For alloxan to
    cause injury to an individual's beta cells, the individual must have
    the genetic susceptibility to injury. This is similar to the connection
    between high-cholesterol foods and heart disease. Eating
    high-cholesterol foods causes heart disease, especially in people who
    have family histories of heart disease. The link between alloxan and
    diabetes is as clear and solid as the link between cholesterol and
    heart disease.

    If you've been eating white bread for years and you have a family
    history of diabetes, all hope is not lost for you. Studies show that
    you can reverse the effects of alloxan by supplementing your diet with
    vitamin E. According to Dr. Gary Null's Clinicians Handbook of Natural
    Healing, vitamin E effectively protected lab rats from the harmful
    effects of administered alloxan. Now, you're not a lab rat, but you're
    a mammal and vitamin E is definitely worth adding to your daily regimen
    of nutritional supplements, especially if you have a history of eating
    foods made with white flour and are at high risk for diabetes.

    Even if you are already diabetic, some simple changes to your diet can
    help treat your diabetes. First of all, stop eating foods made with
    white flour. Even though you already have diabetes, vitamin E
    supplements can still help you, as can many common foods. Garlic, for
    example, does wonders for diabetes. As Dr. Benjamin Lau states in his
    book Garlic for Health, "When fed garlic, the rabbits' elevated blood
    sugar dropped almost as much as it did when they were given the
    antidiabetic drug tolbutamide. Researchers postulated that garlic may
    improve the insulin effect."

    If you can't handle the taste of natural garlic, you can take it in
    widely available supplements. Aloe vera is a traditional diabetic
    remedy in the Arabian Peninsula, and its therapeutic characteristics
    are now gaining worldwide acceptance in the treatment of diabetes.
    According to both human and animal research studies, aloe vera lowers
    blood glucose levels by an unknown mechanism. According to the
    Clinicians Handbook of Natural Healing, this natural hypoglycemic
    effect extended over a period of 24 hours. Adding onions to your diet
    (along with the garlic) can also significantly reduce your blood sugar
    level. Additionally, as Dr. Michael T. Murray writes in The Healing
    Power of Herbs, studies show that ginseng controls glucose in both
    diabetic humans and diabetic laboratory animals.

    It all comes down to asking if putting yourself at risk for diabetic
    coma, blindness, limb amputation and death is worth eating white bread.
    If you're willing to risk your quality of life and your life itself,
    then go ahead and eat all the foods made with white flour you want.
    However, if you want to stop poisoning yourself with alloxan, a known
    toxic chemical, then make a few simple dietary changes. Eat groceries
    (see related ebook on groceries) made with whole-grain wheat flour, not
    processed white flour.

  2. sirenityseekr said:

    Preventive Psychiatry E-Newsletter # 211

    White Flour Contains Diabetes-Causing Contaminant Alloxan

    http://www.newstarget.com/z008191.html

    Sunday, June 19, 2005

    You may want to think twice before eating your next sandwich on white
    bread. Studies show that alloxan, the chemical that makes white flour
    look "clean" and "beautiful," destroys the beta cells of the pancreas.
    That's right; you may be devastating your pancreas and putting yourself
    at risk for diabetes, all for the sake of eating "beautiful" flour. Is
    it worth it?

    Scientists have known of the alloxan-diabetes connection for years; in
    fact, researchers who are studying diabetes commonly use the chemical
    to induce the disorder in lab animals. In the research sense, giving
    alloxan to an animal is similar to injecting that animal with a deadly
    virus, as both alloxan and the virus are being used specifically to
    cause illness. Every day, consumers ingest foods made with
    alloxan-contaminated flour. Would they just as willingly consume foods
    tainted with a deadly virus? Unless they had a death wish, they
    probably would not. Unfortunately, most consumers are unaware of
    alloxan and its potentially fatal link to diabetes because these facts
    are not well publicized by the food industry.

    How does alloxan cause diabetes? According to Dr. Hari Sharma's Freedom
    from Disease, the uric acid derivative initiates free radical damage to
    DNA in the beta cells of the pancreas, causing the cells to malfunction
    and die. When these beta cells fail to operate normally, they no longer
    produce enough insulin, or in other words, they cause one variety of
    adult-onset type 2 diabetes. Alloxan's harmful effects on the pancreas
    are so severe that the Textbook of Natural Medicine calls the chemical
    "a potent beta-cell toxin." However, even though the toxic effect of
    alloxan is common scientific knowledge in the research community, the
    FDA still allows companies to use it when processing foods we ingest.

    The FDA and the white flour industry could counter-argue that, if
    alloxan were to cause diabetes, a higher proportion of Americans would
    be diabetic. After all, more consumers consume white flour on a regular
    basis than are actually diabetic. This point is valid, but it does not
    disprove the alloxan-diabetes connection. While alloxan is one cause of
    adult-onset type 2 diabetes, it is of course not the only cause. As the
    Textbook of Natural Medicine states, "current theory suggests an
    hereditary beta-cell predisposition to injury coupled with some defect
    in tissue regeneration capacity" may be a key cause. For alloxan to
    cause injury to an individual's beta cells, the individual must have
    the genetic susceptibility to injury. This is similar to the connection
    between high-cholesterol foods and heart disease. Eating
    high-cholesterol foods causes heart disease, especially in people who
    have family histories of heart disease. The link between alloxan and
    diabetes is as clear and solid as the link between cholesterol and
    heart disease.

    If you've been eating white bread for years and you have a family
    history of diabetes, all hope is not lost for you. Studies show that
    you can reverse the effects of alloxan by supplementing your diet with
    vitamin E. According to Dr. Gary Null's Clinicians Handbook of Natural
    Healing, vitamin E effectively protected lab rats from the harmful
    effects of administered alloxan. Now, you're not a lab rat, but you're
    a mammal and vitamin E is definitely worth adding to your daily regimen
    of nutritional supplements, especially if you have a history of eating
    foods made with white flour and are at high risk for diabetes.

    Even if you are already diabetic, some simple changes to your diet can
    help treat your diabetes. First of all, stop eating foods made with
    white flour. Even though you already have diabetes, vitamin E
    supplements can still help you, as can many common foods. Garlic, for
    example, does wonders for diabetes. As Dr. Benjamin Lau states in his
    book Garlic for Health, "When fed garlic, the rabbits' elevated blood
    sugar dropped almost as much as it did when they were given the
    antidiabetic drug tolbutamide. Researchers postulated that garlic may
    improve the insulin effect."

    If you can't handle the taste of natural garlic, you can take it in
    widely available supplements. Aloe vera is a traditional diabetic
    remedy in the Arabian Peninsula, and its therapeutic characteristics
    are now gaining worldwide acceptance in the treatment of diabetes.
    According to both human and animal research studies, aloe vera lowers
    blood glucose levels by an unknown mechanism. According to the
    Clinicians Handbook of Natural Healing, this natural hypoglycemic
    effect extended over a period of 24 hours. Adding onions to your diet
    (along with the garlic) can also significantly reduce your blood sugar
    level. Additionally, as Dr. Michael T. Murray writes in The Healing
    Power of Herbs, studies show that ginseng controls glucose in both
    diabetic humans and diabetic laboratory animals.

    It all comes down to asking if putting yourself at risk for diabetic
    coma, blindness, limb amputation and death is worth eating white bread.
    If you're willing to risk your quality of life and your life itself,
    then go ahead and eat all the foods made with white flour you want.
    However, if you want to stop poisoning yourself with alloxan, a known
    toxic chemical, then make a few simple dietary changes. Eat groceries
    (see related ebook on groceries) made with whole-grain wheat flour, not
    processed white flour.

    Al`lox´an
    n. 1. (Chem.) An oxidation product of uric acid. It is of a pale
    reddish color, readily soluble in water or alcohol.

    ---------

    http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=11829314

    The mechanism of alloxan and streptozotocin action in B cells of the
    rat pancreas.

    Szkudelski T.

    Department of Animal Physiology and Biochemistry, University of
    Agriculture, Poznan, Poland.

    Alloxan and streptozotocin are widely used to induce experimental
    diabetes in animals. The mechanism of their action in B cells of the
    pancreas has been intensively investigated and now is quite well
    understood. The cytotoxic action of both these diabetogenic agents is
    mediated by reactive oxygen species, however, the source of their
    generation is different in the case of alloxan and streptozotocin.
    Alloxan and the product of its reduction, dialuric acid, establish a
    redox cycle with the formation of superoxide radicals. These radicals
    undergo dismutation to hydrogen peroxide. Thereafter highly reactive
    hydroxyl radicals are formed by the Fenton reaction. The action of
    reactive oxygen species with a simultaneous massive increase in
    cytosolic calcium concentration causes rapid destruction of B cells.
    Streptozotocin enters the B cell via a glucose transporter (GLUT2) and
    causes alkylation of DNA. DNA damage induces activation of poly
    ADP-ribosylation, a process that is more important for the
    diabetogenicity of streptozotocin than DNA damage itself. Poly
    ADP-ribosylation leads to depletion of cellular NAD+ and ATP. Enhanced
    ATP dephosphorylation after streptozotocin treatment supplies a
    substrate for xanthine oxidase resulting in the formation of superoxide
    radicals. Consequently, hydrogen peroxide and hydroxyl radicals are
    also generated. Furthermore, streptozotocin liberates toxic amounts of
    nitric oxide that inhibits aconitase activity and participates in DNA
    damage. As a result of the streptozotocin action, B cells undergo the
    destruction by necrosis.

    --------

    http://ptcl.chem.ox.ac.uk/MSDS/teratogens.html

    http://www.people.virginia.edu/~rjh9u/terato.html

    http://www.purdue.edu/rem/ih/terat.htm

    ---------

    TC

  3. "sirenityseekr" <[email hidden]> schrieb im Newsbeitrag
    news:[email hidden]...

    Quoted message said:

    Preventive Psychiatry E-Newsletter # 211

    White Flour Contains Diabetes-Causing Contaminant Alloxan

    http://www.newstarget.com/z008191.html

    Sunday, June 19, 2005

    You may want to think twice before eating your next sandwich on white
    bread. Studies show that alloxan, the chemical that makes white flour
    look "clean" and "beautiful," destroys the beta cells of the pancreas.
    That's right; you may be devastating your pancreas and putting yourself
    at risk for diabetes, all for the sake of eating "beautiful" flour. Is
    it worth it?

    Scientists have known of the alloxan-diabetes connection for years; in
    fact, researchers who are studying diabetes commonly use the chemical
    to induce the disorder in lab animals. In the research sense, giving
    alloxan to an animal is similar to injecting that animal with a deadly
    virus, as both alloxan and the virus are being used specifically to
    cause illness. Every day, consumers ingest foods made with
    alloxan-contaminated flour. Would they just as willingly consume foods
    tainted with a deadly virus? Unless they had a death wish, they
    probably would not. Unfortunately, most consumers are unaware of
    alloxan and its potentially fatal link to diabetes because these facts
    are not well publicized by the food industry.

    How does alloxan cause diabetes? According to Dr. Hari Sharma's Freedom
    from Disease, the uric acid derivative initiates free radical damage to
    DNA in the beta cells of the pancreas, causing the cells to malfunction
    and die. When these beta cells fail to operate normally, they no longer
    produce enough insulin, or in other words, they cause one variety of
    adult-onset type 2 diabetes. Alloxan's harmful effects on the pancreas
    are so severe that the Textbook of Natural Medicine calls the chemical
    "a potent beta-cell toxin." However, even though the toxic effect of
    alloxan is common scientific knowledge in the research community, the
    FDA still allows companies to use it when processing foods we ingest.

    The FDA and the white flour industry could counter-argue that, if
    alloxan were to cause diabetes, a higher proportion of Americans would
    be diabetic. After all, more consumers consume white flour on a regular
    basis than are actually diabetic. This point is valid, but it does not
    disprove the alloxan-diabetes connection. While alloxan is one cause of
    adult-onset type 2 diabetes, it is of course not the only cause. As the
    Textbook of Natural Medicine states, "current theory suggests an
    hereditary beta-cell predisposition to injury coupled with some defect
    in tissue regeneration capacity" may be a key cause. For alloxan to
    cause injury to an individual's beta cells, the individual must have
    the genetic susceptibility to injury. This is similar to the connection
    between high-cholesterol foods and heart disease. Eating
    high-cholesterol foods causes heart disease, especially in people who
    have family histories of heart disease. The link between alloxan and
    diabetes is as clear and solid as the link between cholesterol and
    heart disease.

    If you've been eating white bread for years and you have a family
    history of diabetes, all hope is not lost for you. Studies show that
    you can reverse the effects of alloxan by supplementing your diet with
    vitamin E. According to Dr. Gary Null's Clinicians Handbook of Natural
    Healing, vitamin E effectively protected lab rats from the harmful
    effects of administered alloxan. Now, you're not a lab rat, but you're
    a mammal and vitamin E is definitely worth adding to your daily regimen
    of nutritional supplements, especially if you have a history of eating
    foods made with white flour and are at high risk for diabetes.

    Even if you are already diabetic, some simple changes to your diet can
    help treat your diabetes. First of all, stop eating foods made with
    white flour. Even though you already have diabetes, vitamin E
    supplements can still help you, as can many common foods. Garlic, for
    example, does wonders for diabetes. As Dr. Benjamin Lau states in his
    book Garlic for Health, "When fed garlic, the rabbits' elevated blood
    sugar dropped almost as much as it did when they were given the
    antidiabetic drug tolbutamide. Researchers postulated that garlic may
    improve the insulin effect."

    If you can't handle the taste of natural garlic, you can take it in
    widely available supplements. Aloe vera is a traditional diabetic
    remedy in the Arabian Peninsula, and its therapeutic characteristics
    are now gaining worldwide acceptance in the treatment of diabetes.
    According to both human and animal research studies, aloe vera lowers
    blood glucose levels by an unknown mechanism. According to the
    Clinicians Handbook of Natural Healing, this natural hypoglycemic
    effect extended over a period of 24 hours. Adding onions to your diet
    (along with the garlic) can also significantly reduce your blood sugar
    level. Additionally, as Dr. Michael T. Murray writes in The Healing
    Power of Herbs, studies show that ginseng controls glucose in both
    diabetic humans and diabetic laboratory animals.

    It all comes down to asking if putting yourself at risk for diabetic
    coma, blindness, limb amputation and death is worth eating white bread.
    If you're willing to risk your quality of life and your life itself,
    then go ahead and eat all the foods made with white flour you want.
    However, if you want to stop poisoning yourself with alloxan, a known
    toxic chemical, then make a few simple dietary changes. Eat groceries
    (see related ebook on groceries) made with whole-grain wheat flour, not
    processed white flour.

    what are the quantities?
    how much alloxan is there per 100g of white flour?

  4. Quoted message said:
    Quoted message said:

    Scientists have known of the alloxan-diabetes connection for years; in


    fact, researchers who are studying diabetes commonly use the chemical
    to induce the disorder in lab animals. <<

    COMMENT:

    In LAB animals. This is one of those cases where humans differ quite a
    lot from rodents and even dogs in toxicity of a given chemical. We're
    not sure why. It may be that alloxan is toxic mainly in species that
    make their own vitamin C. In flour it probably only gives diabetes to
    the Linus Pauling types who megadose. 🙂

    Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9253-6.

    Major species differences between humans and rodents in the
    susceptibility to
    pancreatic beta-cell injury.

    Eizirik DL, Pipeleers DG, Ling Z, Welsh N, Hellerstrom C, Andersson A.

    Department of Medical Cell Biology, Uppsala University, Sweden.

    The ability of beta cells to endure assaults may be relevant in the
    development
    of insulin-dependent diabetes mellitus. This study examines the
    susceptibility
    of human pancreatic islets to agents that are cytotoxic for rodent beta
    cells--i.e., sodium nitroprusside (NP, a nitric oxide donor),
    streptozotocin
    (SZ), or alloxan. After 5-8 days in tissue culture, human or rodent
    islets were
    exposed for 14 h to NP (50-200 microM) or for 30 min to SZ or alloxan
    (1-3 mM).
    Glucose oxidation by human islets was not reduced by NP, but there was
    a
    dose-dependent inhibition in rat (40-90% inhibition; P < 0.001) and
    mouse
    (10-60% inhibition; P < 0.05) islet glucose oxidation. Glucose (16.7
    mM)-induced
    insulin release by human islets was not impaired after a 30-min
    exposure to SZ
    or alloxan, at concentrations that inhibited insulin release from rat
    (30-80%
    inhibition; P < 0.001) or mouse (10-70% inhibition; P < 0.05) islets.
    The
    viability of human beta cells purified by flow cytometry was not
    affected by SZ
    or alloxan (5 mM), as judged 1 or 4 days after a 10-min exposure and
    subsequent
    culture; these conditions were cytotoxic for rat beta cells, with
    65-95% (P <
    0.01) dead beta cells after 4 days. Human islets transplanted under the
    kidney
    capsule of nude mice were not affected by in vivo alloxan exposure, as
    suggested
    by preserved graft morphology and insulin content, whereas the
    endogenous beta
    cells of the transplanted mice were severely damage (80% decrease in
    pancreatic
    insulin content and morphological signs of beta-cell destruction). Thus
    human
    beta cells are resistant to NP, SZ, or alloxan at concentrations that
    decrease
    survival and function of rat or mouse beta cells. These marked
    interspecies
    differences emphasize the relevance of repair and/or defense mechanisms
    in
    beta-cell destruction and raise the possibility that such differences
    may also
    be present among individuals of the same species.

    PMID: 7937750 [PubMed - indexed for MEDLINE]

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