<[email hidden]> wrote in message
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Quoted message said:"Possibly, but the ratios are most important, not the individual levels.
Slimness, low carb dieting and activity do not rule out insulin
resistance, nor will they necessarily completely reverse it."
Perhaps we are at cross purposes here. My thoughts in the thread have
been with regardd to metabolic syndrome which is diagnosed as a cluster of
symptoms and having some number of that cluster diagnostic. He has only
one of that cluster which includes bmi and level of physical activity and
body shape and lipids as the criteria. His glucose number suggests ir but
even there other endo factors might be at hand aside from level of insulin
and/or ir related to carbohydrate metobolism disorders.
Ir can be reversed in some and glucose level control is the prime step
with or without drugs aiding. When one sees the triglyceride / hdl ratio
fall, as they often do with glucose control, below a ratio of about 3 then
near normal ir is indicated. Among those with good control this is not
uncommon. Weight loss and exercise also intervene in the feedback loops
at the cell level to reverse the endo prompting of ir. A diet high in
saturated fat is also implicated in ir for those with a genetic
disposition for metabolic disorders.
I would suggest both of you look at the definition of metabolic syndrome.
Clinical Identification of Metabolic Syndrome- Any three of the following.
Risk Factor
Abdominal obesity
Men greater than 40 inch waist
Women 35
Triglycerides greater than 150 mg/dl
HDL
Men less than 40 mg/dl
Women 50
Blood pressure greater 130, greater than 84 mmHg
Fasting glucose greater than 110 mg/dl
Some male patients can develop multiple metabolic risk factors when the
waist circumference is only marginally increased 37-39 inches. Some patients
may have a strong genetic contribution to insulin resistance. They should
benefit from change in life habits, similarly to men with categorical
increases in waist circumference.
Overweight and obesity are associated with insulin resistance and the
metabolic syndrome. However, the presence of abdominal obesity is more
highly correlated with the metabolic risk factors than is an elevated body
mass index (BMI). Therefore, the simple measure of waist circumference is
recommended to identify the body weight component of the metabolic syndrome.