Chromium picolinate linked with reduced carbohydrate cravings in people
with atypical depression
http://www.eurekalert.org/pub_releases/2005-09/mba-cpl092805.php
Severe carbohydrate cravers experienced the most benefit from chromium
picolinate supplementation
WHITE PLAINS, NY, September 29, 2005 - A randomized, double-blind,
placebo-controlled study assessing chromium picolinate supplementation
in 113 people with atypical depression found that a subset of patients
who reported the highest levels of carbohydrate cravings demonstrated
significantly greater reductions than the placebo group on four items on
the Hamilton Depression Rating Scale (HAM-D-29): carbohydrate craving,
appetite increase, increased eating, and diurnal variation of feeling
(mood variation throughout the day). The study, published today in the
Journal of Psychiatric Practice, found that 65 percent of the chromium
picolinate patients with high carbohydrate craving versus 33 percent of
those receiving placebo had significantly greater improvements on total
HAM-D-29 scores (p < 0.05). HAM-D-29 is a standard tool commonly used in
assessing severity of symptoms in depressed patients.
Carbohydrate cravings, weight gain and unexplained fatigue are
characteristic symptoms of atypical depression, a common but frequently
undiagnosed depressive disorder affecting up to 42 percent of the 19
million Americans diagnosed with depression. "These results suggest that
the use of chromium picolinate may be beneficial for patients with
atypical depression who also have severe carbohydrate craving," said the
study's lead investigator, John P. Docherty, M.D., president and CEO of
Comprehensive NeuroScience Inc, and adjunct professor of psychiatry at
Weill Medical College of Cornell University. "For years, the link
between depression, insulin sensitivity, and the value of dietary
chromium picolinate has been hinted at in small studies and this trial
may bring us closer to understanding the connection."
Study Design..... snip ....
Conflict of Interst Statement ? ?
Comprehensive NeuroScience, Inc.
Comprehensive NeuroScience, Inc. (CNS) provides products and services
that enhance the efficiencies of knowledge development and clinical care
in neuro-psychopharmacology and related areas. Comprised of three
complementary divisions (Drug Development, Clinical Trials and Medical
Information Technologies), CNS supports the drug development and
treatment process from discovery through clinical trial evaluation to
the synthesis and dissemination of clinically actionable medical
information.
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1) Eat Till SATISFIED, Not STUFFED... Atkins repeated 9 times in the book
2) Exercise: It's Non-Negotiable..... Chapter 22 title, Atkins book
3) Don't Diet Without Supplimental Nutrients... Chapter 23 title, Atkins
book
4) A sensible eating plan, and follow it. (Atkins, Self Made or Other)